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Dynamic Distribution and Postmortem Redistribution of Tramadol in Poisoned Rats

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2021; 45 (2)

In the past dozen years, the cases of tramadol intoxication have become frequent in many countries. Most previous studies focused on tramadol's pharma......

Abnormally High Blood Acetaldehyde Concentrations Suggest Potential Postmortem Ethanol Generation

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2021; 45 (7)

Ethanol is one of the most commonly used and abused substances worldwide. Identifying whether the source of ethanol detected in corpses is antemortem ......

Simultaneous Quantification of 38 Psychotropic Drugs and Relevant Metabolites in Blood using LC-MS-MS

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2021; 45 (4)

The trend for the concomitant prescription of antidepressants and antipsychotics is increasing. This calls for a veracious screening and quantifying m......

Determination of Ethyl Glucuronide and Ethyl Sulfate in Human Whole Blood and Vitreous Humor by LC-MS-MS and Applications to the Interpretation of Postmortem Ethanol Findings

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2021; 45 (5)

Identifying the source of ethanol in a decedent remained a complicated problem for forensic toxicologists because of postmortem ethanol formation. As ......

Screening of Synthetic Cathinones and Metabolites in Dried Blood Spots by UPLC-MS-MS

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2021; 45 (7)

After its use for decades in clinical screening, dried blood spots (DBS) have recently received considerable attention for their application in variou......

Alpha-Methylfentanyl and Beta-Hydroxyfentanyl LC-MS-MS Quantification in Rat Plasma after Long-Term Ethanol Exposure

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2020; 44 (8)

Fentanyl and its analogues are highly abused drugs that dominate the illicit drug trade. alpha-Methylfentanyl (A-F) and beta-hydroxyfentanyl (B-F) are......

The Emergence of Deschloro-N-ethyl-ketamine, a Ketamine Analog, in Drug Seizures and Drug Driving Cases in Hong Kong

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2020; 44 (8)

The study reports the detection of a newly emerged drug, deschloro-N-ethyl-ketamine (2-oxo-PCE), an analog of ketamine, through forensic drug and toxi......

Identification of Unique 4-Methylmethcathinone (4-MMC) Degradation Markers in Putrefied Matrices

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2020; 44 (8)

Drug degradation as a consequence of putrefactive bacterial activity is a well-known factor that affects the identification and quantitation of certai......

Comparison of the Detection Windows of Heroin Metabolites in Human Urine Using Online SPE and LC-MS/MS: Importance of Morphine-3-Glucuronide

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2020; 44 (1)

Heroin abuse is a serious problem that endangers human health and affects social stability. Though often being used as confirmation of heroin use, 6-m......

Pharmacokinetic Study of Multiple Components of Gelsemium elegans in Goats by Ultra-Performance Liquid Chromatography Coupled to Tandem Mass Spectrometry

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2020; 44 (4)

Gelsemium elegans (G. elegans) has been used in traditional Chinese medicine. This plant is highly toxic to humans, but can promote the growth of pigs......

An Experimental Pharmacokinetics Study of Diazepam and Its Metabolites in Oral Fluid of Chinese Population

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2020; 44 (4)

Diazepam abuse is widespread all over the word, leading to an increasing number of forensic cases such as suicide, drug-driving and robbery, but relev......

A Retrospective of Prevalence of Drugs of Abuse by Hair Analysis in Shanghai using LC-MS-MS

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2020; 44 (5)

This study presents a retrospective analysis of the prevalence of drug abuse in Shanghai by hair analysis. Files and toxicology analysis results of a ......

Determination of 5-MeO-DIPT in Human Urine Using Gas Chromatography Coupled with High-Resolution Orbitrap Mass Spectrometry

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2020; 44 (5)

5-Methoxy-N,N-Diisopropyltryptamine (5-MeO-DIPT) is a designer hallucinogen derived from tryptamine and its use has been banned by many countries. In ......

Segmental Analysis of R/S-Methamphetamine and R/S-Amphetamine in Abusers' Head Hair

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2020; 44 (6)

In this study, the relationships between the concentrations of R/S-methamphetamine (MA) and its metabolite R/S-amphetamine (AP), the AP/MA ratio in ha......

Residue Distribution and Depletion of Ractopamine in Goat Tissues After Exposure to Growth-Promoting Dose

期刊: JOURNAL OF ANALYTICAL TOXICOLOGY, 2019; 43 (2)

The objectives of the present study was to investigated the ractopamine (RAC) distribution and depletion process in various tissues of goat including ......

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