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Biallelic NF1 inactivation in high grade serous ovarian cancers from patients with neurofibromatosis type 1

期刊: FAMILIAL CANCER, 2020; 19 (4)

Neurofibromatosis type 1 (NF1) is a multisystem disorder caused by germline heterozygous NF1 loss-of-function variants. The NF1 gene encodes neurofibr......

Association of genetic variations in RTN4 3'-UTR with risk for clear cell renal cell carcinoma

期刊: FAMILIAL CANCER, 2018; 17 (1)

Nogo proteins play an important role in the apoptosis of cells, especially in tumor cells. The present study was conducted to evaluate whether the TAT......

JIF:2.21

Association between miR-146a rs2910164 polymorphism and specific cancer susceptibility: an updated meta-analysis

期刊: FAMILIAL CANCER, 2018; 17 (3)

The rapidly increasing of cancer risk nationwide and worldwide has threatened human health and caused the changes of disease and death spectrum. Micro......

JIF:2.21

Correlation of IL-31 gene polymorphisms with susceptibility and clinical recurrence of bladder cancer

期刊: FAMILIAL CANCER, 2018; 17 (4)

Interleukin-31 is a crucial cytokine triggering inflammation which could be one of the risk factors of tumors. However, data for correlation between I......

JIF:2.21

A lesson from a reported pathogenic variant in Peutz-Jeghers syndrome: a case report

期刊: FAMILIAL CANCER, 2017; 16 (3)

Peutz-Jeghers syndrome (PJS) is a rare autosomal dominant disorder characterized by mucocutaneous hyperpigmentation, gastrointestinal (GI) hamartmatou......

JIF:1.94

The association between prognosis of breast cancer and first-degree family history of breast or ovarian cancer: a systematic review and meta-analysis

期刊: FAMILIAL CANCER, 2017; 16 (3)

Whether a positive family history of breast cancer or ovarian cancer (FHBOC) would affect the prognosis of breast cancer is still up for debate and fu......

JIF:1.94

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