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Regulation of TGF beta/SMAD signaling by long non-coding RNAs in different cancers: Dark Knight in the Castle of molecular oncology

期刊: NON-CODING RNA RESEARCH, 2021; 6 (1)

One of the complex themes in recent years has been the multi-layered regulation of TGF beta signaling in cancer cells. TGF beta/SMAD signaling pathway......

Regulation of RUNX proteins by long non-coding RNAs and circular RNAs in different cancers

期刊: NON-CODING RNA RESEARCH, 2021; 6 (2)

RUNX proteins have been shown to behave as "double-edge sword" in wide variety of cancers. Discovery of non-coding RNAs has played linchpin role in im......

The nuclear functions of long noncoding RNAs come into focus

期刊: NON-CODING RNA RESEARCH, 2021; 6 (2)

Long noncoding RNAs (lncRNAs), defined as untranslated and tightly-regulated transcripts with a length exceeding 200 nt, are common outputs of the euk......

RNA and liquid-liquid phase separation

期刊: NON-CODING RNA RESEARCH, 2021; 6 (2)

Liquid-Liquid Phase Separation (LLPS) is a biological phenomenon that refers to the components of similar properties form droplets condensate in cells......

Non-coding RNAs in exosomes and adipocytes cause fat loss during cancer cachexia

期刊: NON-CODING RNA RESEARCH, 2021; 6 (2)

Cancer Cachexia (CC) is a disease that changes various metabolisms in human body. Fat metabolism is significantly affected in CC, leading to fat loss.......

Long noncoding RNAs as promising biomarkers in cancer

期刊: NON-CODING RNA RESEARCH, 2022; 7 (2)

Despite many advances in diagnosis and therapy (surgery, radiation therapy, chemotherapy), cancer remains one of the most important public health prob......

The role of microRNA in the pathogenesis of glial brain tumors

期刊: NON-CODING RNA RESEARCH, 2022; 7 (2)

Gliomas are the most common and fatal primary brain tumor in adults. Gliomas are highly invasive tumors with the highest mortality among all primary m......

Characterization and bioinformatics analysis of ptc-miR396g-5p in response to drought stress of Paeonia ostii

期刊: NON-CODING RNA RESEARCH, 2022; 7 (3)

Drought is one of the main abiotic stress factors affecting yield of Paeonia ostii. In this study, we conducted bioinformatics and differential expres......

Two lncRNAs, MACC1-AS1 and UCA1, co-mediate the expression of multiple mRNAs through interaction with individual miRNAs in breast cancer cells

期刊: NON-CODING RNA RESEARCH, 2022; 7 (3)

Background: Increasing studies have shown that lncRNAs often play roles through interaction with miRNAs to control gene expression by inhibiting trans......

Hotspots and development frontiers of circRNA based on bibliometric analysis

期刊: NON-CODING RNA RESEARCH, 2022; 7 (2)

Background and purpose: Circular RNAs (circRNAs) are a big group of members of the noncoding RNA family following long non-coding RNA and microRNA. Th......

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