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Effects of the interval between ovulation induction using clomiphene citrate and frozen embryo transfer on pregnancy outcome

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (2)

Objective: To explore the best timing for frozen embryo transfer (FET) after ovarian stimulation and egg retrieval using the clomiphene citrate (CC) +......

Effects of copper-containing intrauterine devices on the endometrium

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (1)

The use of copper-containing intrauterine devices (Cu-IUDs) is a safe, effective, and long-term contraceptive method. Here, we review the effects of C......

Insights into the pathogenesis of preeclampsia based on the features of placentation and tumorigenesis

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (2)

Placentation and tumorigenesis have many common features. Human placentation builds a maternal-fetal connection, circumvents maternal immune rejection......

Risk of adverse perinatal outcomes and antenatal depression based on the zung self-rating depression scale

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (1)

Objective: The aim of the study is to investigate the relationship between antenatal depression and adverse perinatal outcomes. Methods: This prospect......

Efficacy and safety of sanjiezhentong capsules, a traditional chinese patent medicine, on long-term management of endometriosis: A randomized controlled trial

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (1)

Objective: To compare the efficacy of the traditional Chinese medicine SanJieZhenTong (SJZT) capsules versus gonadotropin-releasing hormone analogs (G......

Fertility preservation in cancer patients

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (1)

Traditional radiotherapy and chemotherapy often cause irreversible damage to the fertility and endocrine function of cancer patients. The current meth......

Long-term androgen-induced nonalcoholic fatty liver disease in a polycystic ovary syndrome mouse model is related to mitochondrial dysfunction

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (2)

Objective: Metabolic disorders are markedly common in women with polycystic ovary syndrome (PCOS), and nonalcoholic fatty liver disease (NAFLD) is obs......

Granulosa cell biomarkers to predict oocyte and embryo quality in assisted reproductive technology

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (1)

With the development of human assisted reproductive technology (ART), an objective, accurate, and non-invasive method to assess the quality and viabil......

Research progress on human endometrium decidualization In vitro cell models

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (2)

Decidualization is a special type of differentiation of endometrial stromal cells into secretory decidualized cells, which is closely related to the o......

Syncytin-A knockout induces placental developmental abnormalities partially through calpain1-apoptosis-inducing factor-mediated trophoblast apoptosis

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (2)

Objective: Structural abnormalities and dysfunction of the placenta contribute to pregnancy-related complications, such as preeclampsia. Syncytin-A (s......

MicroRNA-543 in systemic diseases and possible applications in gynecologic tumors

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (2)

In recent years, an increasing number of young women have been diagnosed with cancer, including some nulliparous women. Therefore, many young patients......

Aspirin enhances the protective effect of progesterone on trophoblast cell from oxidative stress and apoptosis

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (1)

Objective: Clinically, low-dose aspirin and progesterone are frequently used to prevent pregnancy loss. We investigated the effect of these drugs on t......

Effects of rosmarinic acid on DNA integrity and H19 differentially methylated region methylation levels in human sperm preserved by freeze-drying

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (1)

Objective: To investigate the effects of rosmarinic acid (RA) on the DNA integrity and methylation levels of the H19 differentially methylated region ......

Clinical application potential of umbilical cord mesenchymal stem cells in chemotherapeutic ovarian failure

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (1)

Chemotherapy is often used for female malignancies, but it can increase the risk of premature ovarian failure in women of reproductive age through dif......

Analysis of the microbiome based on 16S rRNA gene signature in women with preterm versus term birth

期刊: REPRODUCTIVE AND DEVELOPMENTAL MEDICINE, 2021; 5 (2)

Objective: To characterize and compare the microbiome signature in the maternal, intrauterine, and fetal environments and the associated bacterial spe......

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