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Yolk-shell structured Au nanorods@mesoporous silica for gas bubble driven drug release upon near-infrared light irradiation

期刊: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2021; 32 ()

Drug release systems co-encapusulated with ammonium bicarbonate (ABC) could facilitate drug release upon acidic or thermal stimulations to improve the......

Endocytic recycling as cellular trafficking fate of simvastatin-loaded discoidal reconstituted high-density lipoprotein to coordinate cholesterol efflux and drug influx

期刊: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2021; 32 ()

Reconstituted high-density lipoproteins (rHDLs) hold promise as nanocarriers for atherosclerosis-targeted delivery, with biofunctions typified by medi......

Selenium-doped calcium phosphate biomineral reverses multidrug resistance to enhance bone tumor chemotherapy

期刊: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2021; 32 ()

The construction of a functional drug delivery system to reverse the multidrug resistance (MDR) of bone tumors in cases of failed chemotherapy remains......

A pH-responsive photoacoustic imaging probe for tumor pH imaging in vivo based on polyaniline-bovine serum albumin

期刊: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2021; 33 ()

Precise pH detection in tumors can guide the design of pH-responsive drugs and theranostic agents to improve treatment efficacy. However, most reporte......

Multifunctional ZnO@CuS nanoparticles cluster synergize chemotherapy and photothermal therapy for tumor metastasis'

期刊: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2021; 34 ()

The poor drug delivery and unsatisfying therapeutic effects remain to be the primary challenges for cancer therapy. Nanosystem that combines multiple ......

Photothermal therapy enhance the anti-mitochondrial metabolism effect of lonidamine to renal cell carcinoma in homologous-targeted nanosystem

期刊: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2021; 34 ()

Renal cell carcinoma (RCC) is a common malignant tumor of the urinary system with poor prognosis. Therapeutic drugs for RCC can easily develop resista......

Fucoidan-based micelles as P-selectin targeted carriers for synergistic treatment of acute kidney injury

期刊: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2021; 32 ()

Acute kidney injury (AKI) is a life-threatening disease without effective treatment. The utilization of curcumin (Cur) for the treatment of AKI is sti......

Albumin-stabilized layered double hydroxide nanoparticles synergized combination chemotherapy for colorectal cancer treatment

期刊: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2021; 34 ()

Combination chemotherapy with two or more complimentary drugs has been widely used for clinical cancer treatment. However, the efficacy and side effec......

TPGS(2k)-PLGA composite nanoparticles by depleting lipid rafts in colon cancer cells for overcoming drug resistance

期刊: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2021; 35 ()

Recently. studies showed that the drug-resistant cell membranes have formed high-density lipid rafts regions: traditional targeted drug delivery syste......

A novel liposome-polymer hybrid nanoparticles delivering a multi-epitope self-replication DNA vaccine and its preliminary immune evaluation in experimental animals

期刊: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2021; 35 ()

DNA vaccine is an attractive immune platform for the prevention and treatment of infectious diseases, but existing disadvantages limit its use in prec......

Magnetic mesoporous silica nanoparticles-aided dual MR/NIRF imaging to identify macrophage enrichment in atherosclerotic plaques

期刊: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2021; 32 ()

Active foamy macrophage enrichment drives atherosclerotic plaque initiation and evolution, and is the prominent target for precisely identifying vulne......

Exposure-time-dependent subcellular staging of gold nanoparticles deposition and vesicle destruction in mice livers

期刊: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2021; 34 ()

Several advances in nanomedicine have been accompanied by rising concerns about the bioaccumulation and toxicity of gold nanoparticles (AuNPs). Here, ......

Novel nanopolymer RNA therapeutics normalize human diabetic corneal wound healing and epithelial stem cells'

期刊: NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE, 2021; 32 ()

Human diabetic corneas develop delayed wound healing, epithelial stem cell dysfunction, recurrent erosions, and keratitis. Adenoviral gene therapy mod......

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