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Glucagon 100 years. Important, but still enigmatic

期刊: PEPTIDES, 2023; 161 ()

Glucagon was discovered in 1923 as a contaminant of early insulin preparations, and its hormonal status was not established until its structure was es......

The role of orexinergic system in the regulation of cataplexy

期刊: PEPTIDES, 2023; 169 ()

Loss of orexin/hypocretin causes serious sleep disorder; narcolepsy. Cataplexy is the most striking symptom of narcolepsy, characterized by abrupt mus......

Leupeptin maintains redox homeostasis via targeting ROS-autophagy-inflammatory axis in LPS-stimulated macrophages and cytokines dichotomy in Con-A challenged lymphocyte

期刊: PEPTIDES, 2023; 168 ()

Information regarding cellular anti-inflammatory and immunomodulatory attributes of leupeptin with respect to modulation of perturbed macrophage funct......

Identification of GDF15 peptide fragments inhibiting GFRAL receptor signaling

期刊: PEPTIDES, 2023; 168 ()

Growth differentiation factor 15 (GDF15) is believed to be a major causative factor for cancer-induced cachexia. Recent elucidation of the central cir......

Post-prandial secretion of glucagon-like peptide-2 (GLP-2) after carbohydrate-, fat- or protein enriched meals in healthy subjects

期刊: PEPTIDES, 2023; 169 ()

Glucagon-like peptide 2 (GLP-2) is an important regulator of intestinal growth and function. In adherable mixed meals the macronutrient composition wi......

Effects of chronically exogenous oxytocin on ovary and uterus: A comparison of intraperitoneal and intranasal administration

期刊: PEPTIDES, 2023; 165 ()

Oxytocin (OT) has been studied as a therapeutic neuropeptide in various diseases, but its effect on the ovary and uterus is not fully known. This stud......

A review of the antiviral activity of cationic antimicrobial peptides

期刊: PEPTIDES, 2023; 166 ()

Viral epidemics are occurring frequently, and the COVID-19 viral pandemic has resulted in at least 6.5 million deaths worldwide. Although antiviral th......

FAM3D: A gut secreted protein and its potential in the regulation of glucose metabolism

期刊: PEPTIDES, 2023; 167 ()

The number of diabetic patients is rising globally and concomitantly so do the diabetes associated complications. The gut secretes a variety of protei......

Investigation of irisin?s role in pubertal onset physiology in female rats

期刊: PEPTIDES, 2023; 163 ()

Objective: The timing of pubertal development is closely related to metabolic status and energy reserves. It is thought that irisin, which is involved......

Screening potential hypertensive peptides using two consecutive bioassay-guided SPE fractionations and identification of an ACE inhibitory peptide, DHSTAVW (DW7), derived from pearl garlic protein hydrolysate

期刊: PEPTIDES, 2023; 167 ()

The pearl garlic (Allium sativum L.) protein (PGP) was digested using pepsin, trypsin, & alpha;-chymotrypsin, thermolysin, and simulated gastroint......

Postnatal ontogeny of Neuromedin S and its receptors NMUR1 and NMUR2 expression in mouse testis

期刊: PEPTIDES, 2023; 159 ()

Neuromedin S (NMS) is a well-known anorexigenic neuropeptide. Despite some reports of the presence of its transcript and precursor protein in testis, ......

An update on peptide-based therapies for type 2 diabetes and obesity

期刊: PEPTIDES, 2023; 161 ()

Long-acting analogues of the naturally occurring incretin, glucagon-like peptide-1 (GLP-1) and those modified to interact also with receptors for gluc......

The LL-37 domain: A clue to cathelicidin immunomodulatory response?

期刊: PEPTIDES, 2023; 165 ()

Host defense peptides (HDPs) are naturally occurring polypeptide sequences that, in addition to being active against bacteria, fungi, viruses, and oth......

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