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DESIGN, SYNTHESIS AND BIOLOGICAL EVALUATION OF PYRIMIDINAMINE DERIVATIVES CONTAINING UREA MOIETY

期刊: HETEROCYCLES, 2023; 106 (1)

- New series of 17 pyrimidinamine derivatives containing urea moiety were designed and synthesized. Their antitumor activity was investigated by MTT m......

SYNTHESIS AND CHARACTERIZATION OF SOME NOVEL HETEROANNULATED CHROMENO[4,3-b]QUINOLINES

期刊: HETEROCYCLES, 2023; 106 (1)

The recently synthesized 1-chloro-11-oxo-3,4-dihydro-11H-chromeno[4,3-b]quinoline-2-carboxaldehyde (1) was efficiently utilized as a key precursor to ......

SIMULTANEOUS DENITRATIVE C-C BOND FORMATION AND CONSTRUCTION OF PYRAZOLE RING LEADING TO 1,1'-DIPHENYL-4,4'-BIPYRAZOLE

期刊: HETEROCYCLES, 2023; 106 (1)

--Formy1-13-nitroenamine reacts with phenylhydrazine to afford 1,1'-diphenyl-4,4'-bipyrazole. The unusual C -C bond formation was found to proceed in ......

COMPREHENSIVE SYNTHESIS OF 20 FENTANYL DERIVATIVES FOR THEIR RAPID DIFFERENTIATION BY GC-MS ANALYSIS

期刊: HETEROCYCLES, 2023; 106 (1)

Fentanyl, a selective agonist of opioid & mu; receptors, is a broadly used clinical agent for anesthesia and pain relief. Despite its clinical ben......

ACID, METAL AND PEROXIDE-FREE SYNTHESIS OF 2,4,5-TRISUBSTITUTED IMIDAZOLES COMMENCING FROM INTERNAL ALKENES USING AN IODINE/DMSO SYSTEM

期刊: HETEROCYCLES, 2023; 106 (1)

- An efficient acid, metal and peroxide-free synthesis of 2,4,5-trisubstituted imicla7oles commencing from internal alkenes and aldehydes using an ine......

CATALYST-FREE GREEN SYNTHESIS OF PHTHALAZINONES AT ROOM TEMPERATURE

期刊: HETEROCYCLES, 2023; 106 (1)

An efficient catalyst-free synthesis of phthalazinones from 2-formyl/acetyl/benzoylbenzoic acids and substituted hydrazines is described. The direct c......

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