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The cell type-specific ER membrane protein UGS148 is not essential in mice

期刊: GENES TO CELLS, 2022; 27 (1)

Genomes of higher eukaryotes encode many uncharacterized proteins, and the functions of these proteins cannot be predicted from the primary sequences ......

JIF:1.725

Characterization of phalloidin-negative nuclear actin filaments in U2OS cells expressing cytoplasmic actin-EGFP

期刊: GENES TO CELLS, 2022; 27 (5)

Actin is a major structural component of the cytoskeleton in eukaryotic cells, including fungi, plants, and animals, and exists not only in the cytopl......

JIF:1.725

The structure-function analysis of Obg-like GTPase proteins along the evolutionary tree from bacteria to humans

期刊: GENES TO CELLS, 2022; 27 (7)

Obg proteins belong to P-loop guanine triphosphatase (GTPase) that are conserved from bacteria to humans. Like other GTPases, Obg cycles between guani......

JIF:1.725

N-terminal Ago-binding domain of GW182 contains a tryptophan-rich region that confer binding to the CCR4-NOT complex

期刊: GENES TO CELLS, 2022; 27 (9)

GW182 family proteins are a key component of microRNA-protein complex eliciting translational repression and/or degradation of microRNA-targets. The m......

JIF:1.725

Local anesthetic lidocaine induces growth suppression of HeLa cells by decreasing and changing the cellular localization of the proliferation marker Ki-67

期刊: GENES TO CELLS, 2022; 27 (11)

Although surgery is a basic therapy for cancer, it causes inflammation and immunosuppression, often resulting in recurrence and metastasis. Previous s......

JIF:1.725

Vrk2 deficiency elicits aggressive behavior in female zebrafish

期刊: GENES TO CELLS, 2022; 27 (4)

Vaccinia-related kinase 2 (VRK2) is a serine/threonine kinase initially identified in highly proliferative cells such as thymocytes and fetal liver ce......

JIF:1.725

Roles of the second messenger c-di-GMP in bacteria: Focusing on the topics of flagellar regulation and Vibrio spp.

期刊: GENES TO CELLS, 2022; 27 (3)

Typical second messengers include cyclic AMP (cAMP), cyclic GMP (cGMP), and inositol phosphate. In bacteria, cyclic diguanylate (c-di-GMP), which is n......

JIF:1.725

Epithelial miR-215 negatively modulates Th17-dominant inflammation by inhibiting CXCL12 production in the small intestine

期刊: GENES TO CELLS, 2022; 27 (4)

MicroRNAs are a class of non-coding short-chained RNAs that control cellular functions by downregulating their target genes. Recent research indicates......

JIF:1.725

LincRNA-p21 exon 1 expression correlates with Cdkn1a expression in vivo

期刊: GENES TO CELLS, 2022; 27 (1)

LincRNA-p21 is a long intergenic non-coding RNA (LincRNA) gene reported to activate the transcription of the adjacent Cdkn1a (p21) gene in cis. The im......

JIF:1.725

Identification of responsible amino acid residues in staphylococcal superantigen-like 12 for the activation of mast cells

期刊: GENES TO CELLS, 2022; 27 (9)

Staphylococcal superantigen-like 12 (SSL12) is reported to evoke the degranulation in murine mast cells. The allelic variant of SSL12 in the genome of......

JIF:1.725

Egg components reverse the atrophy induced by injury in skeletal muscles

期刊: GENES TO CELLS, 2022; 27 (2)

Skeletal muscle atrophy is the loss of muscle tissue caused by factors such as inactivity, malnutrition, aging, and injury. In this study, we aimed to......

JIF:1.725

Biochemical propensity mapping for structural and functional anatomy of importin alpha IBB domain

期刊: GENES TO CELLS, 2022; 27 (3)

Importin alpha has been described as a nuclear protein transport receptor that enables proteins synthesized in the cytoplasm to translocate into the n......

JIF:1.725

Mapping of the regions implicated in nuclear localization of multi-functional DNA repair endonuclease XPF-ERCC1

期刊: GENES TO CELLS, 2022; 27 (5)

The structure-specific endonuclease XPF-ERCC1 is a multi-functional heterodimer that participates in a variety of DNA repair mechanisms for maintainin......

JIF:1.725

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