期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (4)
Pdia4 has been characterized as a key protein that positively regulates beta-cell failure and diabetes via ROS regulation. Here, we investigated the f......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (6)
Antimicrobial peptides (AMPs) are major components of the innate immune defense. Accumulating evidence suggests that the antibacterial activity of man......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (12)
BackgroundHuntington's Disease (HD) is a disorder that affects body movements. Altered glutamatergic innervation of the striatum is a major hallmark o......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (12)
A common perception in age-related neurodegenerative diseases posits that a decline in proteostasis is key to the accumulation of neuropathogenic prot......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (1)
Adequate endometrial growth is a critical factor for successful embryo implantation and pregnancy maintenance. We pre-viously reported the efficacy of......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (1)
The myelin sheath is an essential structure for the rapid transmission of electrical impulses through axons, and peripheral myelination is a well-prog......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (4)
Neurotrypsin (NT) is a neuronal trypsin-like serine protease whose mutations cause severe mental retardation in humans. NT is activated in vitro by He......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (6)
Tumors create an immunosuppressive tumor microenvironment by altering protein expression, but also by changing their glycosylation status, like altere......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (6)
Amyotrophic lateral sclerosis (ALS) is the most common motor neuron (MN) disease in adults with no curative treatment. Neurofilament (NF) level in pat......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (8)
Microenvironmental factors are known fundamental regulators of the phenotype and aggressiveness of glioblastoma (GBM), the most lethal brain tumor, ch......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (1)
In recent years, there has been growing interest in SARM1 as a potential breakthrough drug target for treating various pathologies of axon degeneratio......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (2)
Chemokine ligands and receptors regulate the directional migration of leukocytes. Post-translational modifications of chemokine receptors including O-......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (3)
Replication of viruses requires interaction with host cell factors and repression of innate immunity. Recent findings suggest that a subset of intrace......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (7)
DIS3L2 degrades different types of RNAs in an exosome-independent manner including mRNAs and several types of non-coding RNAs. DIS3L2-mediated degrada......
期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2023; 80 (8)
AimsArrhythmogenic cardiomyopathy (AC) is a severe heart disease predisposing to ventricular arrhythmias and sudden cardiac death caused by mutations ......