文献资料信息综合查询系统
筛选条件 共查询到500条结果
排序方式
Dynamic changes in peripheral blood monocytes early after anti-PD-1 therapy predict clinical outcomes in hepatocellular carcinoma

期刊： CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; 72 (2)

Immune checkpoint inhibitors are effective for advanced hepatocellular carcinoma (HCC), but there remains a need for peripheral blood biomarkers to pr......

PD-L1 antibody enhanced β-glucan antitumor effects via blockade of the immune checkpoints in a melanoma model

期刊： CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; 72 (3)

In the tumor microenvironment (TME), one of the major functions of tumor-recruited CD11b(+) cells are the suppression of the T-cell-mediated anti-tumo......

Induction of the activating transcription factor-4 in the intratumoral CD8+T cells sustains their viability and anti-tumor activities

期刊： CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; 72 (4)

Immune suppressive factors of the tumor microenvironment (TME) undermine viability and exhaust the activities of the intratumoral cytotoxic CD8 + T ly......

Effectiveness of pembrolizumab in trial-ineligible patients with metastatic urothelial carcinoma

期刊： CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; 72 (4)

Background The KEYNOTE-045 trial showed that pembrolizumab therapy improved the survival of patients with advanced urothelial carcinoma (UC). However,......

Efficacy and safety of immune checkpoint inhibitors in elderly patients with primary liver cancer: a retrospective, multicenter, real-world cohort study

期刊： CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; 72 (7)

BackgroundThere is still no specific real-world data regarding the clinical activity of immune checkpoint inhibitors in the elderly with liver cancer.......

IL13Rα2-targeted third-generation CAR-T cells with CD28 transmembrane domain mediate the best anti-glioblastoma efficacy

期刊： CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; 72 (7)

Chimeric antigen receptor (CAR)-modified T (CAR-T) cell therapy has been proven to be a powerful tool for the treatment of cancer, however, the limits......

Characteristic differences in the abundance of tumor-infiltrating lymphocytes and intratumoral developing T cells in thymoma, with special reference to PD-1 expression

期刊： CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; 72 (8)

PurposeThough programmed cell death-1 (PD-1) inhibitors mainly target tumor-infiltrating lymphocytes (TILs) expressing PD-1, developing T cells in thy......

Radiation-induced dormancy of intracerebral melanoma: endotoxin inflammation leads to both shortened tumor dormancy and long-term survival with localized senescence

期刊： CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; ()

Radiation therapy (RT) treats approximately half of all cancers and most brain cancers. RT is variably effective at inducing a dormant tumor state i.e......

An optimized protocol for the generation and monitoring of conditional orthotopic lung cancer in the KP mouse model using an adeno-associated virus vector compatible with biosafety level 1

期刊： CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; ()

BackgroundThe inducible Kras/p53 lung adenocarcinoma mouse model, which faithfully recapitulates human disease, is routinely initiated by the intratra......

Apolipoprotein C-III itself stimulates the Syk/cPLA2-induced inflammasome activation of macrophage to boost anti-tumor activity of CD8+ T cell

期刊： CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; ()

Increased prevalence of cancer in obese individuals is involved with dyslipidemia- induced chronic inflammation and immune suppression. Although apoli......

Long-term outcomes of patients with recurrent ovarian cancer treated with a polyvalent vaccine with bevacizumab combination

期刊： CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; 72 (1)

Background To characterize the safety, immunogenicity, and outcomes of patients with high-grade serous ovarian cancer (HGSOC) in second or greater rem......

Different effects of NK cells and NK-derived soluble factors on cell lines derived from primary or metastatic pancreatic cancers

期刊： CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; 72 (6)

Natural killer (NK) cells are cytotoxic lymphoid cells that play a key role in defenses against tumors. However, their function may be severely impair......

LILRB2-containing small extracellular vesicles from glioblastoma promote tumor progression by promoting the formation and expansion of myeloid-derived suppressor cells

期刊： CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; 72 (7)

Background Leukocyte immunoglobulin-like receptor subfamily B2 (LILRB2) was reported to be an inhibitory molecule with suppressive functions. sEVs med......

Effectiveness and safety of radiotherapy plus programmed death-1 inhibitors and lenvatinib in patients with advanced biliary tract carcinoma: a real-world study

期刊： CANCER IMMUNOLOGY IMMUNOTHERAPY, 2023; 72 (7)

BackgroundRadiotherapy (RT) may function synergistically with immunotherapy and targeted agents (TA). This study aimed to assess the effectiveness and......

共500条页码: 1/34页15条/页