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Ageing male (part I): Pathophysiology and diagnosis of functional hypogonadism

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (4)

This narrative review summarizes key points of the pathogenesis and diagnosis of the ageing-related decline of testosterone (T) in men. The condition ......

JIF:4.084

Novel androgen therapies including selective androgen receptor modulators

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (5)

Male hypogonadism is associated with reduced quality of life and the development of co-morbidities including obesity, diabetes mellitus, and dyslipida......

JIF:4.084

Androgens and male sexual function

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (4)

Sexual symptoms are the most specific determinants of low testosterone (T) observed during adulthood. In this narrative re-view, we summarize the most......

JIF:4.084

Treatments of psychiatric disorders, hyperprolactinemia and dopamine agonists

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (6)

While the prevalence of hyperprolactinemia under antidepres-sants is very low, its prevalence under antipsychotics, particularly of the first generati......

JIF:4.084

Androgens, sports, and detection strategies for anabolic drug use

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (4)

For decades, anabolic androgenic agents have represented the substance class most frequently observed in doping control sam-ples. They comprise synthe......

JIF:4.084

How best to monitor the specific side effects of medical treatments of Cushing's disease

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (6)

The first-line treatment of Cushing's disease is transsphenoidal surgery. Medical treatment of Cushing's disease can be considered in several situatio......

JIF:4.084

Ageing male (part 2): Management of functional hypogonadism in older men, a patient-centric holistic approach

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (4)

The diagnosis of functional hypogonadism should prompt a thor-ough assessment and optimization of general health, including lifestyle changes, weight ......

JIF:4.084

Safety of androgen therapy in men with prostate cancer

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (5)

Prostate cancer is one of the most frequently diagnosed malig-nancies in men worldwide and the life expectancy for men with prostate cancer is improvi......

JIF:4.084

Common symptoms associated with usage and cessation of anabolic androgenic steroids in men

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (5)

Anabolic-androgenic steroid (AAS) have widespread and growing illicit use as image and performance enhancing drugs (IPED), predominantly in young men.......

JIF:4.084

Genetics of cryptorchidism and testicular regression

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (1)

Cryptorchidism, i.e., undescended testis, is one of the most common genital malformations in newborn male babies. The birth rate of cryptorchidism var......

JIF:4.084

Acquisition of peak bone mass

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (2)

Peak bone mass (PBM) is a key determinant of bone mass and fragility fractures later in life. The increase in bone mass during childhood and adolescen......

JIF:4.084

Genetic variants of gonadotrophins and their receptors: Impact on the diagnosis and management of the infertile patient

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (1)

This narrative review is concerned with genetic variants of the genes encoding gonadotrophin subunits and their receptors, as well as their implicatio......

JIF:4.084

The effect of osteoporosis treatment on bone mass

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (2)

Over the last two decades there have been significant de-velopments in the pharmacotherapy of osteoporosis. The thera-peutic arsenal has expanded with......

JIF:4.084

Morbidity and mortality in men: Role of androgens

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (4)

In this narrative review we provide an overview of the current literature on male hypogonadism and related comorbidities, also depicting the role of t......

JIF:4.084

Genetics of congenital central hypogonadism

期刊: BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM, 2022; 36 (1)

The diagnostic suspicion of congenital central hypogonadism is based on clinical signs. Biochemical confirmation is challenging, especially after the ......

JIF:4.084

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