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Validation and clinical evaluation of an ultra-performance liquid chromatography with ultraviolet detector method for plasma quantification of micafungin

期刊: ANNALS OF CLINICAL BIOCHEMISTRY, 2023; 60 (3)

Background Factors associated with interindividual variability in the pharmacokinetics of micafungin have been identified. This variability can cause ......

Increased PD-1 expression of bone marrow T-cells in acute myeloid leukaemia patients after stem cell transplantation, and its association with overall survival

期刊: ANNALS OF CLINICAL BIOCHEMISTRY, 2023; ()

Background: Immune checkpoints are involved in mechanisms by which tumours escape from the host immune system. Our aim was to evaluate acute myeloid l......

Effect of automated feedback laboratory comments promoting good phlebotomy practice on the frequency of ethylenediaminetetraacetic acid (EDTA) contamination of serum samples

期刊: ANNALS OF CLINICAL BIOCHEMISTRY, 2023; 60 (1)

Background Ethylenediaminetetraacetic acid (EDTA) contamination of serum samples is common but under-recognized unless EDTA is measured. Incorrect ord......

Utilising routine clinical laboratory data to support quality improvement in health care: Application of a national acute kidney injury alert system as a proof of concept

期刊: ANNALS OF CLINICAL BIOCHEMISTRY, 2023; ()

Background: Acute kidney injury (AKI) is a global health issue known to cause avoidable harm and death. Improvement in its prevention and management i......

Reference ranges of thyroid hormones during the first trimester in Catalan women using the Atellica® IM Solution Immunoassay Analyzer

期刊: ANNALS OF CLINICAL BIOCHEMISTRY, 2023; ()

Background: Gestational hypothyroidism has been shown to be associated with adverse pregnancy outcomes as well as adverse outcomes for the child. Thyr......

Establishment of reference intervals for plasma metanephrines in seated position measured by LC-MS/MS and assessment of diagnostic performance in pheochromocytoma/paraganglioma

期刊: ANNALS OF CLINICAL BIOCHEMISTRY, 2023; 60 (3)

Background The use of supine reference intervals instead of the corresponding seated reference intervals for seated plasma-free metanephrines (MNs) in......

Key methodological challenges in detecting circulating miRNAs in different biofluids

期刊: ANNALS OF CLINICAL BIOCHEMISTRY, 2023; 60 (1)

The technological advancement in diagnostic techniques has immensely improved the capability of predicting disease progression. Yet, there is a great ......

Paediatric reference ranges for plasma chromogranin A

期刊: ANNALS OF CLINICAL BIOCHEMISTRY, 2023; ()

Background: Neuroendocrine neoplasms (NENs) are a heterogeneous group of rare diseases with varied aggressiveness originating from endocrine cells bel......

The clinical and laboratory impact of reporting faecal elastase-1 in watery stool samples

期刊: ANNALS OF CLINICAL BIOCHEMISTRY, 2023; 60 (1)

Background Low faecal elastase-1 (FE-1) results are suggestive of pancreatic insufficiency, but watery diarrhoea may lead to falsely low results. Meth......

Current practice and recommendations for managing transgender patient data in clinical laboratories in the United Kingdom and Republic of Ireland

期刊: ANNALS OF CLINICAL BIOCHEMISTRY, 2023; ()

Background: Transgender people may avoid seeking medical care due to previous negative experiences and fear of discrimination. Clinical laboratories c......

Replicate and repeat faecal immunochemical tests in symptomatic patients: A systematic review

期刊: ANNALS OF CLINICAL BIOCHEMISTRY, 2023; 60 (1)

Background Faecal Immunochemical tests (FITs) in the assessment of patients presenting with symptoms have generally used a single sample. Little evide......

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