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Aerobic Cu(I)-Catalyzed Site-Selective 1,3-Difunctionalization of Indazole through Cascade C-N and C-O Bond Formation

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; 365 (3)

A Cu(I)-catalyzed 1,3 oxo alkylation of indazole has been developed for constructing N-1-alkylated indazolone derivatives. This cascade reaction invol......

Chemo- and Diastereoselective Synthesis of Polyheterocycles by Rhodium(III)-Catalyzed sp2/sp3 C-H Activation of 2-Arylquinazolin-4(3H)-ones with 3-Methylmaleimides

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; 365 (9)

Rhodium(III)-catalyzed sp(2)/sp(3) C-H activation/annulation of 2-arylquinazolin-4(3H)-ones with 3-methylmaleimides is explored. This protocol provide......

Differentiating the Allyl and Propargyl Groups on α-Quaternary Carboxylic Acids via Chiral Bifunctional Sulfide-Catalyzed Kinetic Resolution

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; 365 (9)

Catalytic kinetic resolution of racemic organic compounds is a reliable method to enantioselectively prepare important chiral molecules. Substrates fo......

Platinum Catalysed Hydrostannylation of Terminal Alkynes; Highly Selective Synthesis of Vinyl Stannanes

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; 365 (10)

We present the first study on the application of platinum complexes in the hydrostannylation of terminal alkynes. A range of platinum complexes were s......

A Direct Silver-Catalyzed Three-Component Approach to Trifluoromethylated Cyanopyrazoles and Cyanopyrazolines

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; 365 (13)

A three-component strategy for the synthesis of an important class of trifluoromethylated cyanopyrazoles from aldehydes, malononitrile and trifluorodi......

Chemical Modification of Peptides and Proteins Using Spirooxindole Oxirane Derivatives

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; 365 (13)

Methods for chemical modification of proteins and peptides at certain positions are required for the preparation of antibody-drug conjugates, protein-......

Metal-Free One-Pot Tandem Construction of C4-Phosphorylated Phthalazin-1(2H)-ones under Visible-Light Photoredox Catalysis

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; 365 (17)

Visible-light photoredox-catalyzed metal-free one-pot tandem regioselective synthesis of C4-phosphorylated phthalazin-1(2H)-ones from arylhydrazines, ......

Navigating Visible-Light-Triggered (aza and thia) Paterno-Buchi Reactions for the Synthesis of Heterocycles

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; ()

Harnessing visible light to trigger (aza and thia) Paterno-Buchi reaction injects new vitality into [2+2] photocyclization reaction and enable impress......

Visible Light Induced Difunctional Hetero-Annulation of Unsaturated C-C Bonds

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; 365 (19)

Heterocyclic scaffolds are beneficial structural architects in a wide range of pharmaceuticals, agrochemicals, biological and also functional material......

Recent Advances in the Functionalization of Remote C-H Bonds by Hofmann-Löffler-Freytag-type Reactions

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; 365 (19)

Nitrogen radicals are one of the most useful reactive intermediates for selective transposition via intramolecular hydrogen atom transfer (HAT). The H......

Cascade Wolff Rearrangement and Double N-Acylation: A Cyclization of a-Diazoketones with 2-aminopyridines or 3-aminopyrazoles to Synthesize Fused Pyrimidinediones

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; 365 (23)

A cascade Wolff rearrangement and double N-acylation reaction has been developed for the synthesis of fused pyrimidinediones in one-pot under air. The......

Visible-Light-Catalyzed Formal [3+2] Annulation-Aromatization of Amidines with Isoquinolinium N-Ylides: Access to Imidazo[2,1-a]isoquinolines

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; ()

A visible-light-catalyzed formal [3+2] annulation-aromatization reaction for the synthesis of various substituted imidazo[2,1-a]isoquinolines from ami......

Asymmetric Organocatalyzed Phospha-Michael Addition for the Direct Synthesis of Biologically Active Chromenylphosphonates

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; 365 (19)

The potential of phosphites as nucleophiles for the asymmetric synthesis of chiral chromene derivatives has been overlooked in the literature. Herein,......

Rapid Access to γ,γ-Dichloroketones via Radical-Induced Dichloromethylation and Concomitant 1,2-Aryl Migration of Allylic Alcohols with CHCl3

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; ()

A radical-induced dichloromethylation and concomitant 1,2-aryl migration of allylic alcohols with CHCl3 is developed for the construction of gamma,gam......

Light-induced FeCl3-catalyzed selective benzyl C-H chlorination with trifluoromethanesulfonyl chloride

期刊: ADVANCED SYNTHESIS & CATALYSIS, 2023; 365 (23)

Here we report a light-induced FeCl3-catalyzed approach for benzyl C-H chlorination with remarkable regioselectivity, which enables alkylbenzenes to b......

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