Mechanics regulates biological processes at the molecular, cellular, tissue, organ, and organism levels. The goal of this journal is to promote basic and applied research that integrates the expanding knowledge-bases in the allied fields of biomechanics and mechanobiology. Approaches may be experimental, theoretical, or computational; they may address phenomena at the nano, micro, or macro levels. Of particular interest are investigations that quantify the mechanical environment in health, disease, or injury; report discoveries that advance therapeutic and diagnostic procedures; detail inter-relations between mechanics and the associated biological processes, including growth, remodeling, and repair, and identify and quantify mechanosensitive responses and their mechanisms. Especially encouraged are analytical and computational models based on solid mechanics, fluid mechanics, or thermomechanics, and their interactions; also encouraged are reports on new experimental methods that expand measurement capabilities and new mathematical methods that facilitate analysis.