The International Journal of Colorectal Disease aims to publish novel and state-of-the-art papers which deal with the physiology and pathophysiology of diseases involving the entire gastrointestinal tract. In addition to original research articles of high scientific quality reviews will be included and controversial issues from rapidly developing areas in gastroenterology and gastrointestinal surgery addressed. The Journal offers its readers an interdisciplinary forum for clinical science and molecular research related to colorectal disease.