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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1953 1
1964 1
1965 1
1966 1
1968 4
1971 5
1972 2
1973 2
1974 2
1975 8
1976 11
1977 3
1978 15
1979 16
1980 15
1981 27
1982 45
1983 44
1984 46
1985 42
1986 48
1987 90
1988 136
1989 144
1990 172
1991 186
1992 206
1993 236
1994 274
1995 306
1996 312
1997 331
1998 419
1999 502
2000 582
2001 759
2002 953
2003 1161
2004 1380
2005 1580
2006 1708
2007 2023
2008 2286
2009 2543
2010 3129
2011 3725
2012 4242
2013 5512
2014 8594
2015 11199
2016 11241
2017 11423
2018 14731
2019 18082
2020 21758
2021 26620
2022 28235
2023 28421
2024 7972

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199,275 results

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Page 1
The Frequency of Ras Mutations in Cancer.
Prior IA, Hood FE, Hartley JL. Prior IA, et al. Cancer Res. 2020 Jul 15;80(14):2969-2974. doi: 10.1158/0008-5472.CAN-19-3682. Epub 2020 Mar 24. Cancer Res. 2020. PMID: 32209560 Free PMC article. Review.
Ras is frequently mutated in cancer, however, there is a lack of consensus in the literature regarding the cancer mutation frequency of Ras, with quoted values varying from 10%-30%. This variability is at least in part due to the selective aggregation of data from d …
Ras is frequently mutated in cancer, however, there is a lack of consensus in the literature regarding the cancer mutation fre …
Emerging Role of CRISPR/Cas9 Technology for MicroRNAs Editing in Cancer Research.
Aquino-Jarquin G. Aquino-Jarquin G. Cancer Res. 2017 Dec 15;77(24):6812-6817. doi: 10.1158/0008-5472.CAN-17-2142. Epub 2017 Dec 5. Cancer Res. 2017. PMID: 29208606 Review.
MicroRNAs (miRNA) are small, noncoding RNA molecules with a master role in the regulation of important tasks in different critical processes of cancer pathogenesis. Because there are different miRNAs implicated in all the stages of cancer, for example, functioning a …
MicroRNAs (miRNA) are small, noncoding RNA molecules with a master role in the regulation of important tasks in different critical processes …
Computational Radiomics System to Decode the Radiographic Phenotype.
van Griethuysen JJM, Fedorov A, Parmar C, Hosny A, Aucoin N, Narayan V, Beets-Tan RGH, Fillion-Robin JC, Pieper S, Aerts HJWL. van Griethuysen JJM, et al. Cancer Res. 2017 Nov 1;77(21):e104-e107. doi: 10.1158/0008-5472.CAN-17-0339. Cancer Res. 2017. PMID: 29092951 Free PMC article.
Radiomics aims to quantify phenotypic characteristics on medical imaging through the use of automated algorithms. Radiomic artificial intelligence (AI) technology, either based on engineered hard-coded algorithms or deep learning methods, can be used to develop noninvasive …
Radiomics aims to quantify phenotypic characteristics on medical imaging through the use of automated algorithms. Radiomic artificial intell …
Cancer-Associated Fibroblasts in Pancreatic Ductal Adenocarcinoma Determine Response to SLC7A11 Inhibition.
Sharbeen G, McCarroll JA, Akerman A, Kopecky C, Youkhana J, Kokkinos J, Holst J, Boyer C, Erkan M, Goldstein D, Timpson P, Cox TR, Pereira BA, Chitty JL, Fey SK, Najumudeen AK, Campbell AD, Sansom OJ, Ignacio RMC, Naim S, Liu J, Russia N, Lee J, Chou A, Johns A, Gill AJ, Gonzales-Aloy E, Gebski V, Guan YF, Pajic M, Turner N, Apte MV, Davis TP, Morton JP, Haghighi KS, Kasparian J, McLean BJ, Setargew YF, Phillips PA; Australian Pancreatic Cancer Genome Initiative. Sharbeen G, et al. Cancer Res. 2021 Jul 1;81(13):3461-3479. doi: 10.1158/0008-5472.CAN-20-2496. Epub 2021 May 12. Cancer Res. 2021. PMID: 33980655
Cancer-associated fibroblasts (CAF) are major contributors to pancreatic ductal adenocarcinoma (PDAC) progression through protumor signaling and the generation of fibrosis, the latter of which creates a physical barrier to drugs. ...
Cancer-associated fibroblasts (CAF) are major contributors to pancreatic ductal adenocarcinoma (PDAC) progression through protumor si
M2 Macrophage-Derived Exosomes Promote Cell Migration and Invasion in Colon Cancer.
Lan J, Sun L, Xu F, Liu L, Hu F, Song D, Hou Z, Wu W, Luo X, Wang J, Yuan X, Hu J, Wang G. Lan J, et al. Cancer Res. 2019 Jan 1;79(1):146-158. doi: 10.1158/0008-5472.CAN-18-0014. Epub 2018 Nov 6. Cancer Res. 2019. PMID: 30401711
Mechanistically, miR-21-5p and miR-155-5p were transferred to colorectal cancer cells by MDE and bound to the BRG1 coding sequence, downregulating expression of BRG1, which has been identified as a key factor promoting the colorectal cancer metastasis, yet is downre …
Mechanistically, miR-21-5p and miR-155-5p were transferred to colorectal cancer cells by MDE and bound to the BRG1 coding sequence, d …
Dysregulation of Mitochondrial Translation Caused by CBFB Deficiency Cooperates with Mutant PIK3CA and Is a Vulnerability in Breast Cancer.
Malik N, Kim YI, Yan H, Tseng YC, du Bois W, Ayaz G, Tran AD, Vera-Ramirez L, Yang H, Michalowski AM, Kruhlak M, Lee M, Hunter KW, Huang J. Malik N, et al. Cancer Res. 2023 Apr 14;83(8):1280-1298. doi: 10.1158/0008-5472.CAN-22-2525. Cancer Res. 2023. PMID: 36799863 Free PMC article.
Understanding functional interactions between cancer mutations is an attractive strategy for discovering unappreciated cancer pathways and developing new combination therapies to improve personalized treatment. ...SIGNIFICANCE: CBFB-regulated mitochondrial translati …
Understanding functional interactions between cancer mutations is an attractive strategy for discovering unappreciated cancer
Intratumoral Copper Modulates PD-L1 Expression and Influences Tumor Immune Evasion.
Voli F, Valli E, Lerra L, Kimpton K, Saletta F, Giorgi FM, Mercatelli D, Rouaen JRC, Shen S, Murray JE, Ahmed-Cox A, Cirillo G, Mayoh C, Beavis PA, Haber M, Trapani JA, Kavallaris M, Vittorio O. Voli F, et al. Cancer Res. 2020 Oct 1;80(19):4129-4144. doi: 10.1158/0008-5472.CAN-20-0471. Epub 2020 Aug 18. Cancer Res. 2020. PMID: 32816860
Here we show that intratumoral copper levels influence PD-L1 expression in cancer cells. Deep analysis of the The Cancer Genome Atlas database and tissue microarrays showed strong correlation between the major copper influx transporter copper transporter 1 (CTR-1) a …
Here we show that intratumoral copper levels influence PD-L1 expression in cancer cells. Deep analysis of the The Cancer Genom …
Meta-Analysis of Human Cancer Single-Cell RNA-Seq Datasets Using the IMMUcan Database.
Camps J, Noël F, Liechti R, Massenet-Regad L, Rigade S, Götz L, Hoffmann C, Amblard E, Saichi M, Ibrahim MM, Pollard J, Medvedovic J, Roider HG, Soumelis V. Camps J, et al. Cancer Res. 2023 Feb 3;83(3):363-373. doi: 10.1158/0008-5472.CAN-22-0074. Cancer Res. 2023. PMID: 36459564 Free PMC article.
The development of single-cell RNA sequencing (scRNA-seq) technologies has greatly contributed to deciphering the tumor microenvironment (TME). ...We have developed IMMUcan scDB (https://immucanscdb.vital-it.ch), a fully integrated scRNA-seq database exclusively dedicated …
The development of single-cell RNA sequencing (scRNA-seq) technologies has greatly contributed to deciphering the tumor microenvironm …
Genome Medicine in Cancer: What's in a Name?
Schott AF, Perou CM, Hayes DF. Schott AF, et al. Cancer Res. 2015 May 15;75(10):1930-5. doi: 10.1158/0008-5472.CAN-15-0174. Epub 2015 Apr 28. Cancer Res. 2015. PMID: 25920349 Review.
This is an exciting time to be in cancer medicine. New technologies, such as next-generation sequencing (NGS), have increased our understanding of the molecular aberrations that define cancer. ...Unfortunately, unclear or incorrect use of the new terminology …
This is an exciting time to be in cancer medicine. New technologies, such as next-generation sequencing (NGS), have increased …
CRISPR-Cas13 Precision Transcriptome Engineering in Cancer.
Granados-Riveron JT, Aquino-Jarquin G. Granados-Riveron JT, et al. Cancer Res. 2018 Aug 1;78(15):4107-4113. doi: 10.1158/0008-5472.CAN-18-0785. Epub 2018 Jul 18. Cancer Res. 2018. PMID: 30021724 Review.
All of these properties give us a glimpse about the potential of the CRISPR toolkit for precise transcriptome engineering, possibly leading to an expansion of CRISPR technologies for cancer therapeutics and diagnostics. Here, we examine previously unaddressed aspect …
All of these properties give us a glimpse about the potential of the CRISPR toolkit for precise transcriptome engineering, possibly leading …
199,275 results
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