心血管

订阅

MedSci主页 / 所有栏目 / 心血管

Diabetes：夜间低血糖致糖尿病患者心律失常风险高

2014-04-30 永远 编译 中国医学论坛报

低血糖糖尿病心律失常
关注

一项英国研究显示，在心血管高危2型糖尿病患者中，夜间低血糖增加心律失常发生风险。研究者认为，这可能是强化降糖治疗时心血管死亡风险增加的原因之一。论文发表在《糖尿病》(Diabetes)5月刊。 该研究纳入25例接受胰岛素治疗、有心血管病史或≥2种心血管危险因素的2型糖尿病患者，动态监测血糖和心电图。结果为，共检测到134小时低血糖、65小时高血糖和1258小时正常血糖。与低血糖相比，夜间低血糖期

一项英国研究显示，在心血管高危2型糖尿病患者中，夜间低血糖增加心律失常发生风险。研究者认为，这可能是强化降糖治疗时心血管死亡风险增加的原因之一。论文发表在《糖尿病》(Diabetes)5月刊。

该研究纳入25例接受胰岛素治疗、有心血管病史或≥2种心血管危险因素的2型糖尿病患者，动态监测血糖和心电图。结果为，共检测到134小时低血糖、65小时高血糖和1258小时正常血糖。与低血糖相比，夜间低血糖期间心动过缓和心房、心室异位搏动计数显著较多。夜间低血糖期间心律失常较日间低血糖更频繁。在一些患者中，发生低血糖期间可观察到校正心率QT间期>500 ms和异常T波形态。

原始出处：


Chow E1, Bernjak A, Williams S, Fawdry RA, Hibbert S, Freeman J, Sheridan PJ, Heller SR.Risk of cardiac arrhythmias during hypoglycemia in patients with type 2 diabetes and cardiovascular risk.Diabetes. 2014 May;63(5):1738-47. doi: 10.2337/db13-0468.

版权声明：
本网站所有内容来源注明为“梅斯医学”或“MedSci原创”的文字、图片和音视频资料，版权均属于梅斯医学所有。非经授权，任何媒体、网站或个人不得转载，授权转载时须注明来源为“梅斯医学”。其它来源的文章系转载文章，或“梅斯号”自媒体发布的文章，仅系出于传递更多信息之目的，本站仅负责审核内容合规，其内容不代表本站立场，本站不负责内容的准确性和版权。如果存在侵权、或不希望被转载的媒体或个人可与我们联系，我们将立即进行删除处理。
在此留言
评论区 (4)
#插入话题
  1. [GetPortalCommentsPageByObjectIdResponse(id=1636856, encodeId=30d2163685600, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Sep 24 17:15:00 CST 2014, time=2014-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901206, encodeId=838a1901206e9, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Tue Jul 22 14:15:00 CST 2014, time=2014-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759437, encodeId=08d51e59437c6, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Wed Nov 12 00:15:00 CST 2014, time=2014-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473788, encodeId=e79814e378803, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri May 02 04:15:00 CST 2014, time=2014-05-02, status=1, ipAttribution=)]
    2014-09-24 ms9608593228839890

    #DIA#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1636856, encodeId=30d2163685600, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Sep 24 17:15:00 CST 2014, time=2014-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901206, encodeId=838a1901206e9, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Tue Jul 22 14:15:00 CST 2014, time=2014-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759437, encodeId=08d51e59437c6, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Wed Nov 12 00:15:00 CST 2014, time=2014-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473788, encodeId=e79814e378803, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri May 02 04:15:00 CST 2014, time=2014-05-02, status=1, ipAttribution=)]
    2014-07-22 木头人513

    #Diabetes#

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1636856, encodeId=30d2163685600, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Sep 24 17:15:00 CST 2014, time=2014-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901206, encodeId=838a1901206e9, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Tue Jul 22 14:15:00 CST 2014, time=2014-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759437, encodeId=08d51e59437c6, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Wed Nov 12 00:15:00 CST 2014, time=2014-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473788, encodeId=e79814e378803, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri May 02 04:15:00 CST 2014, time=2014-05-02, status=1, ipAttribution=)]
    2014-11-12 智智灵药

    #BET#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1636856, encodeId=30d2163685600, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Wed Sep 24 17:15:00 CST 2014, time=2014-09-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1901206, encodeId=838a1901206e9, content=<a href='/topic/show?id=c097591ed5' target=_blank style='color:#2F92EE;'>#Diabetes#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5917, encryptionId=c097591ed5, topicName=Diabetes)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0045169, createdName=木头人513, createdTime=Tue Jul 22 14:15:00 CST 2014, time=2014-07-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1759437, encodeId=08d51e59437c6, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=41, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Wed Nov 12 00:15:00 CST 2014, time=2014-11-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1473788, encodeId=e79814e378803, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Fri May 02 04:15:00 CST 2014, time=2014-05-02, status=1, ipAttribution=)]
    2014-05-02 xue8604

    #糖尿病患者#

    0

相关资讯

Diabetes Care：严重低血糖或与2型糖尿病患者癌症发生率较高相关

中国香港学者探讨了2型糖尿病患者发生严重低血糖的临床情况与其临床转归(包括死亡和所有部位癌症发生)的相关性，结果表明，严重低血糖与高龄、肾功能不全、血糖控制不佳和癌症亚表现[低体质指数(BMI)、低水平的低密度脂蛋白胆固醇(LDL-C)和低甘油三酯(TG)]存在相关性。论文2月10日在线发表于《糖尿病护理》(Diabetes Care)杂志。【原文下载】 研究纳入8767例在入组前的12

PNAS：婚姻不幸或与低血糖有关

低血糖可能会导致伴侣间的攻击行为，就像这个巫毒娃娃所代表的那样 图片来源：Brad Bushman 如果你对伴侣感到怒不可遏，或许应该检查一下自己的血糖。一项新的研究表明，血液中的葡萄糖水平如果很低（俗称低血糖），可能会增加夫妻之间的愤怒和攻击行为。研究人员指出，他们的发现暗示了葡萄糖与自我控制之间的一种关联，然而也有专家对这项研究的意义不以为然。 葡

Gastroenterology：阻断GLP-1受体或可治疗胃旁路术后低血糖

2013年底，《胃肠病学》Gastroenterology杂志在线发表了“阻断胰高血糖素样肽1（GLP-1）受体治疗胃旁路术后低血糖”一文，为低血糖这一胃旁路术后难治并发症的治疗带来了新的启示。2014年1月27日在线发表的同期述评则对其中的可能机制进行了详细介绍。在此汇集整理部分重点内容，以飨读者。 美国与意大利的一项联合研究表明，胰高血糖素样肽1（GLP-1）受体拮抗剂可纠正胃旁路术

Lancet：食糖舌下给药可治疗小儿低血糖症

Deborah Harris及其同事研究发现，在具有低血糖危险因素的婴儿中，葡萄糖凝胶作为一种非侵入性治疗方法，能安全有效的治疗新生儿低血糖。而且，葡萄糖凝胶还可降低患儿重症监护病房入住率，以及对静脉输注葡萄糖和人工喂养的需求。该研究结果发表在2013年12月21日的The Lancet杂志上。 在低血糖发生率和漏诊率均比较高的资源匮乏地区，迫切需要这种治疗方法。然而，葡萄糖凝胶制剂的费用和

Diabetes Care：动态血糖监测或可减少严重低血糖发生

为了评价动态血糖监测（CGM）对无意识性低血糖患者严重低血糖（SH）频率的影响。来自英国伦敦国王学院糖尿病和营养科学部的Choudhary等进行了一项研究，发现CGM能够减少SH发生频率，同时改善HbA1c水平。研究结果在线发表于2013年10月8日的美国《糖尿病治疗》（Diabetes Care）杂志上。【原文下载】 研究人员对35名1型糖尿病和可疑无意识性低血糖患

陆志强：减少低血糖，糖尿病管理当务之急

美国临床内分泌医师协会最近公布了新的2型糖尿病治疗指南。新指南强调，减少低血糖发生风险是糖尿病管理的当务之急，因为这关系到治疗的安全性和治疗的成本。低血糖可能让糖尿病患者出现饥饿、颤抖、出汗、头疼头晕、甚至昏迷等不适。轻到中度的低血糖发作会对患者的社会活动、睡眠、情绪等造成影响。而重度低血糖则会明显增加患者的心血管风险和死亡风险，一次严重低血糖或因此诱发的心血管事件可能会抵