胰腺癌的发生还与晒太阳有关?

2015-05-08 佚名 生物谷

近日,来自美国加州大学圣地亚哥分校的研究人员在国际学术期刊the Journal of Steroid Biochemistry and Molecular Biology在线发表了一项最新研究进展,他们发现胰腺癌发生率在光照较少的国家发生率最高,这种关联性可能与维生素D的合成有关。 在该项研究中,研究人员对来自107个国家的人群数据进行了分析,并将国家间差异以及饮酒、肥胖和吸烟情况考虑

近日,来自美国加州大学圣地亚哥分校的研究人员在国际学术期刊the Journal of Steroid Biochemistry and Molecular Biology在线发表了一项最新研究进展,他们发现胰腺癌发生率在光照较少的国家发生率最高,这种关联性可能与维生素D的合成有关。
 
在该项研究中,研究人员对来自107个国家的人群数据进行了分析,并将国家间差异以及饮酒、肥胖和吸烟情况考虑在内。结果发现生活在高纬度或云层较厚区域的人,一年中大部分时间都不能够合成维生素D,这可能是导致胰腺癌发生风险高于正常水平的重要原因。同时,生活在赤道附近阳光充足区域的人们其胰腺癌发生率仅是远离赤道区域的人们的六分之一,这表明维生素D的缺陷可能是促进胰腺癌发生风险的重要因素。
 
自然界中含有维生素D的天然食物种类较少,除了从食物中摄取维生素D,人体还需要通过皮肤在阳光下照射下进行维生素D的合成,但隔着窗户在室内进行阳光照射并不能产生维生素D。
 
之前一些研究已经发现血清中的一种维生素D代谢产物与乳腺癌结肠癌发生有关,而这项研究首次提出维生素D缺陷与胰腺癌发生有关。
 
胰腺癌是世界上排名第十二位的常见癌症,每年诊断出大约338,000名病人患有胰腺癌,并且胰腺癌的致死率非常高,该项研究发现胰腺癌的发生可能与光照产生的维生素D水平有关,对于阐述胰腺癌发生的地域差异具有一定意义。

原始出处:


Cedric F. Garland, Raphael E. Cuomo, Edward D. Gorham, Kenneth Zeng, Sharif B. Mohr. Cloud cover-adjusted ultraviolet B irradiance and pancreatic cancer incidence in 172 countries. The Journal of Steroid Biochemistry and Molecular Biology, 2015; DOI: 10.1016/j.jsbmb.2015.04.004

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  1. [GetPortalCommentsPageByObjectIdResponse(id=1951631, encodeId=ec5119516316a, content=<a href='/topic/show?id=bd5259e63d9' target=_blank style='color:#2F92EE;'>#晒太阳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59763, encryptionId=bd5259e63d9, topicName=晒太阳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=325a197, createdName=amyloid, createdTime=Sun May 17 11:26:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33443, encodeId=e387334434d, content=懂了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a25c1635554, createdName=byzh1990, createdTime=Sat Jul 25 03:27:00 CST 2015, time=2015-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=27727, encodeId=15942e727ae, content=多晒啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acd01628312, createdName=1dd82894m82(暂无匿称), createdTime=Tue Jun 16 01:57:00 CST 2015, time=2015-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23031, encodeId=ca8c230315a, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Sat May 09 07:16:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23016, encodeId=9c76230166d, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Fri May 08 22:37:00 CST 2015, time=2015-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22957, encodeId=2b902295e5b, content=有道理,,,,, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f0451620298, createdName=CCLJ, createdTime=Fri May 08 21:35:00 CST 2015, time=2015-05-08, status=1, ipAttribution=)]
    2015-05-17 amyloid
  2. [GetPortalCommentsPageByObjectIdResponse(id=1951631, encodeId=ec5119516316a, content=<a href='/topic/show?id=bd5259e63d9' target=_blank style='color:#2F92EE;'>#晒太阳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59763, encryptionId=bd5259e63d9, topicName=晒太阳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=325a197, createdName=amyloid, createdTime=Sun May 17 11:26:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33443, encodeId=e387334434d, content=懂了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a25c1635554, createdName=byzh1990, createdTime=Sat Jul 25 03:27:00 CST 2015, time=2015-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=27727, encodeId=15942e727ae, content=多晒啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acd01628312, createdName=1dd82894m82(暂无匿称), createdTime=Tue Jun 16 01:57:00 CST 2015, time=2015-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23031, encodeId=ca8c230315a, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Sat May 09 07:16:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23016, encodeId=9c76230166d, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Fri May 08 22:37:00 CST 2015, time=2015-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22957, encodeId=2b902295e5b, content=有道理,,,,, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f0451620298, createdName=CCLJ, createdTime=Fri May 08 21:35:00 CST 2015, time=2015-05-08, status=1, ipAttribution=)]
    2015-07-25 byzh1990

    懂了

    0

  3. [GetPortalCommentsPageByObjectIdResponse(id=1951631, encodeId=ec5119516316a, content=<a href='/topic/show?id=bd5259e63d9' target=_blank style='color:#2F92EE;'>#晒太阳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59763, encryptionId=bd5259e63d9, topicName=晒太阳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=325a197, createdName=amyloid, createdTime=Sun May 17 11:26:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33443, encodeId=e387334434d, content=懂了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a25c1635554, createdName=byzh1990, createdTime=Sat Jul 25 03:27:00 CST 2015, time=2015-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=27727, encodeId=15942e727ae, content=多晒啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acd01628312, createdName=1dd82894m82(暂无匿称), createdTime=Tue Jun 16 01:57:00 CST 2015, time=2015-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23031, encodeId=ca8c230315a, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Sat May 09 07:16:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23016, encodeId=9c76230166d, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Fri May 08 22:37:00 CST 2015, time=2015-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22957, encodeId=2b902295e5b, content=有道理,,,,, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f0451620298, createdName=CCLJ, createdTime=Fri May 08 21:35:00 CST 2015, time=2015-05-08, status=1, ipAttribution=)]
    2015-06-16 1dd82894m82(暂无匿称)

    多晒啊!

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=1951631, encodeId=ec5119516316a, content=<a href='/topic/show?id=bd5259e63d9' target=_blank style='color:#2F92EE;'>#晒太阳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59763, encryptionId=bd5259e63d9, topicName=晒太阳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=325a197, createdName=amyloid, createdTime=Sun May 17 11:26:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33443, encodeId=e387334434d, content=懂了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a25c1635554, createdName=byzh1990, createdTime=Sat Jul 25 03:27:00 CST 2015, time=2015-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=27727, encodeId=15942e727ae, content=多晒啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acd01628312, createdName=1dd82894m82(暂无匿称), createdTime=Tue Jun 16 01:57:00 CST 2015, time=2015-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23031, encodeId=ca8c230315a, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Sat May 09 07:16:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23016, encodeId=9c76230166d, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Fri May 08 22:37:00 CST 2015, time=2015-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22957, encodeId=2b902295e5b, content=有道理,,,,, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f0451620298, createdName=CCLJ, createdTime=Fri May 08 21:35:00 CST 2015, time=2015-05-08, status=1, ipAttribution=)]
    2015-05-09 zhouanxiu

    有用

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=1951631, encodeId=ec5119516316a, content=<a href='/topic/show?id=bd5259e63d9' target=_blank style='color:#2F92EE;'>#晒太阳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59763, encryptionId=bd5259e63d9, topicName=晒太阳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=325a197, createdName=amyloid, createdTime=Sun May 17 11:26:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33443, encodeId=e387334434d, content=懂了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a25c1635554, createdName=byzh1990, createdTime=Sat Jul 25 03:27:00 CST 2015, time=2015-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=27727, encodeId=15942e727ae, content=多晒啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acd01628312, createdName=1dd82894m82(暂无匿称), createdTime=Tue Jun 16 01:57:00 CST 2015, time=2015-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23031, encodeId=ca8c230315a, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Sat May 09 07:16:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23016, encodeId=9c76230166d, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Fri May 08 22:37:00 CST 2015, time=2015-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22957, encodeId=2b902295e5b, content=有道理,,,,, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f0451620298, createdName=CCLJ, createdTime=Fri May 08 21:35:00 CST 2015, time=2015-05-08, status=1, ipAttribution=)]
    2015-05-08 huaxipanxing

    看看

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1951631, encodeId=ec5119516316a, content=<a href='/topic/show?id=bd5259e63d9' target=_blank style='color:#2F92EE;'>#晒太阳#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=59763, encryptionId=bd5259e63d9, topicName=晒太阳)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=325a197, createdName=amyloid, createdTime=Sun May 17 11:26:00 CST 2015, time=2015-05-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33443, encodeId=e387334434d, content=懂了, beContent=null, objectType=article, channel=null, level=null, likeNumber=107, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a25c1635554, createdName=byzh1990, createdTime=Sat Jul 25 03:27:00 CST 2015, time=2015-07-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=27727, encodeId=15942e727ae, content=多晒啊!, beContent=null, objectType=article, channel=null, level=null, likeNumber=115, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=acd01628312, createdName=1dd82894m82(暂无匿称), createdTime=Tue Jun 16 01:57:00 CST 2015, time=2015-06-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23031, encodeId=ca8c230315a, content=有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=99, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3yz0JbjHQ7nicJU7lHMOu0Itf3Zv3VBzEvK3k4AFPBXhiaxIRNGVI33GicoRXQEjkaasjdlWKwZuwcyhDP9Jibqt5ct/0, createdBy=f1281613275, createdName=zhouanxiu, createdTime=Sat May 09 07:16:00 CST 2015, time=2015-05-09, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=23016, encodeId=9c76230166d, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Fri May 08 22:37:00 CST 2015, time=2015-05-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=22957, encodeId=2b902295e5b, content=有道理,,,,, beContent=null, objectType=article, channel=null, level=null, likeNumber=114, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f0451620298, createdName=CCLJ, createdTime=Fri May 08 21:35:00 CST 2015, time=2015-05-08, status=1, ipAttribution=)]
    2015-05-08 CCLJ

    有道理,,,,

    0

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