Eur J Cancer:胃切除术后一年BMI可预测胃癌患者的长期生存情况

2016-01-18 Seven L 译 MedSci原创

胃癌患者术前BMI和术后生存率间的联系目前不明确,此外术后BMI对生存的影响也不清楚,而胃切除术后出现体重下降是不可避免的。研究者纳入了1909名胃癌切除术的胃癌患者,根据患者BMI将其分为三组:低 (<18.5 kg/m(2))、正常(18.5-24.9 kg/m(2))、高(≥25.0 kg/m(2))。在基线和术后1年比较不同BMI组的患者生存情况。研究数据显示,胃切除术后一年高BMI

胃癌患者术前BMI和术后生存率间的联系目前不明确,此外术后BMI对生存的影响也不清楚,而胃切除术后出现体重下降是不可避免的。研究者纳入了1909名胃癌切除术的胃癌患者,根据患者BMI将其分为三组:低 (<18.5 kg/m2)、正常(18.5-24.9 kg/m2)、高(≥25.0 kg/m2)。在基线和术后1年比较不同BMI组的患者生存情况。

研究数据显示,胃切除术后一年高BMI组与正常组或低BMI组比较,整体生存、疾病特异性生存和无复发生存时间均更长。校正患者年龄、性别、手术方式、肿瘤分期、组织学、根治性切除术等混杂因素后,Cox比例风险模型分析显示,术后一年高BMI组与正常组比较,整体死亡率更低(HR 0.51; 95% CI, 0.26-0.98)。不过基线BMI并不是独立的预后因素。

研究结果表明,与术前BMI相比,术后一年BMI可预测胃切除术后胃癌患者的长期生存。

原始出处:


Lee HH, Park JM,et al.Survival impact of postoperative body mass index in gastric cancer patients undergoing gastrectomy.Eur J Cancer. 2016 Jan;52:129-37.

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    2016-01-20 bshuang
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