J Gastroen Hepatol:BMI与食管癌风险研究

2019-11-18 MedSci MedSci原创

体重过低、超重及肥胖均可导致食管癌风险增加

在过去的几十年里,大量的文献报道了体重指数(BMI)与食管癌(EC)风险之间的关系,但这些结果并不一致。近日研究人员开展Meta分析,探讨BMI与EC(包括食管鳞状细胞癌(ESCC)和食管腺癌(EADC))的关系。

研究收集了截至2018年底的相关研究文献,总计涉及25个相关研究,包含16561名患者以及11954161名对照志愿者。

研究发现,与正常体重者相比比较,体重过轻与EC(rr=1.78)和ESCC(rr=1.57)风险有显著的相关性。超重和肥胖都会增加EADC风险(rr=1.56;rr=2.34),但却可降低食管鳞癌的风险(rr=0.71;rr=0.63)。肥胖与EC总体风险增加相关(rr=1.51)。

研究认为,体重过低、超重及肥胖均可导致食管癌风险增加。

原始出处:


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    2020-07-20 许安
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    2019-12-23 sjq027
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    2019-11-20 gwc384
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    2019-11-20 zhouqu_8

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