NEJM:体重变化与冠心病预后

2017-04-06 MedSci MedSci原创

冠心病患者的体重增长会大幅提高心血管事件发生率

体重因素是无心血管疾病患者死亡和冠状动脉事件的危险因素之一,但目前还不知道体重的变化是否会影响冠心病患者的预后。

对此研究人员,对冠心病患者体重变化进行分析并研究使用阿托伐他汀降低低密度脂蛋白胆固醇水平的有效性和安全性。研究主要终点是任何冠状动脉事件发生率(包括冠心病死亡、非致死性心肌梗死、心脏骤停复苏、血管重建或心绞痛);次要终点为任意心血管事件 (冠状动脉事件、脑血管事件、外周血管疾病或心力衰竭) 死亡、心肌梗死或中风的发生率。

结果显示,研究涉及的9509名患者,其体重增长导致所有试验终点风险发生率上升:冠状动脉事件2091起、心血管事件2727起、死亡487起;相比于体重增长最少的患者,体重增长最多的患者冠状动脉事件发生率升高64%,心血管事件发生率升高85%;死亡风险提高124%;心肌梗死率升高117%,中风风险升高136%。

研究表明,冠心病患者的体重增长会大幅提高心血管事件发生率,带来严重的危害。

原文出处:

Lucie A. van den Berg et al. Two-Year Outcome after Endovascular Treatment for Acute Ischemic Stroke N Engl J Med. April 6 2017

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    2017-05-03 137****4081

    文章有立意

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    2017-04-07 owlhealth

    能否看到全文

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    2017-04-06 1ddf0692m34(暂无匿称)

    保持健康的生活方式

    0