Neuroradiology:玩转DTI之利用DTI和神经生理学评价腰神经完整性和功能间的关系。

2017-07-27 shaosai MedSci原创

尽管利用扩散张量成像(DTI)研究腰神经的最好方法尚不明确,但它在评价外周神经的完整性方面展现了极大的潜力。本研究旨在利用改良DTI技术来评估腰神经的完整性及其与神经生理学功能结果之间的相关性,并将结果发表在Neuroradiology上。

尽管利用扩散张量成像(DTI)研究腰神经的最好方法尚不明确,但它在评价外周神经的完整性方面展现了极大的潜力。本研究旨在利用改良DTI技术来评估腰神经的完整性及其与神经生理学功能结果之间的相关性,并将结果发表在Neuroradiology上

本研究共纳入了20例健康志愿者并对L5/S1区域进行3T DTI扫描。感兴趣区包括L5和S1神经根。收集DTI测量参数(部分各向异性(FA)、平均扩散系数(MD)、轴位扩散系数(AD)和径向扩散系数(RD))。神经生理学参数来源于L5/S1神经支配的肌肉电生理检查,主要包括运动诱发电位的输入-输出曲线的斜率、F波潜伏期、最大运动反应和中枢及外周运动传导时间。

结果为,在双侧腰神经及椎体水平间的DTI数据相似。相反,在神经根的不同节段,DTI数据大小差异较大。回归分析表明L5神经根的DTI数据与由L5神经根支配肌肉所得的电生理学结果具有相关性。

本研究表明,DTI具有评估腰神经完整性的潜能,DTI数据提供了反应神经功能的定量性信息。

原始出处:

Chiou SY, Hellyer PJ, Sharp DJ, et al. Relationships between the integrity and function of lumbar nerve roots as assessed by diffusion tensor imaging and neurophysiology.Neuroradiology. 2017.DOI: 10.1007/s00234-017-1869-0

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    2017-08-08 whlxd
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    2017-07-29 huagfeg
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    2017-07-28 刘煜

    学习了谢谢分享

    0

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    2017-07-28 龙胆草

    学习谢谢分享

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    2017-07-28 meiliwuxian

    学习了

    0