Eur Heart J:警惕睡不好,心衰风险增加!

2021-08-16 MedSci原创 MedSci原创

失眠症状,无论是累积的还是单独的,都与HF发生相关。应鼓励公众健康意识以及对高危人群失眠症状进行筛查,以降低HF发生率。

心力衰竭(HF)是一种广泛流行的疾病,是严重的临床和公共卫生问题。目前,人们对失眠症状与HF发病率之间的前瞻性关联知之甚少。

近日,血管领域权威杂志Eur Heart J上发表了一篇研究文章,研究人员旨在调查随时间变化的失眠症状(难以入睡、难以维持睡眠、清晨醒来、非恢复性睡眠)与HF之间的纵向关联。

该研究的数据来自美国健康与退休研究,涉及12761名中年和老年人(年龄≥50岁;平均[SD]年龄为66.7[9.4]岁;57.7%为女性)。2002年基线时没有HF。受访者对HF事件进行了16年的随访。研究人员采用边际结构离散时间生存分析来调整潜在的随时间变化的生物、心理认知和行为因素,并解释由于不同失访造成的偏差。

在基线时,38.4%的受访者报告至少经历过一种失眠症状。在16年的随访期间,1730名受访者发生了HF。经历了1种(风险比[HR]=1.22;95%CI为1.08–1.38)、2种(HR=1.45;95%CI为1.21–1.72)、3种(HR=1.66;95%CI为1.37–2.02)或4种(HR=1.80;95%CI为1.25-2.59)失眠症状的受访者比无症状受访者发生HF的风险更高。难以入睡(HR=1.17;95%CI为1.01–1.36)、维持睡眠(HR=1.14;95%CI为1.01–1.28)、早醒(HR=1.20;95%CI:1.02–1.43)或非恢复性睡眠(HR=1.25;95%CI为1.06–1.46)的受访者发生HF的风险高于无症状受访者。
 
由此可见,失眠症状,无论是累积的还是单独的,都与HF发生相关。应鼓励公众健康意识以及对高危人群失眠症状进行筛查,以降低HF发生率。

原始出处:

Asos Mahmood.et al.Insomnia symptoms and incident heart failure: a population-based cohort study.European Heart Journal.2021.https://doi.org/10.1093/eurheartj/ehab500

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    2022-05-14 stfoxst
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    2021-08-18 zhaojie88
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    2021-08-18 slcumt
  5. [GetPortalCommentsPageByObjectIdResponse(id=1800728, encodeId=e4d01800e281a, content=<a href='/topic/show?id=6759e29628f' target=_blank style='color:#2F92EE;'>#睡不好#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=72962, encryptionId=6759e29628f, topicName=睡不好)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=1a19115, createdName=stfoxst, createdTime=Sat May 14 08:23:56 CST 2022, time=2022-05-14, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1357763, encodeId=1ceb135e76361, content=<a href='/topic/show?id=b0702e84b9' target=_blank style='color:#2F92EE;'>#ART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=43, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2784, encryptionId=b0702e84b9, topicName=ART)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4c37265, createdName=zhaojie88, createdTime=Wed Aug 18 09:23:56 CST 2021, time=2021-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1389482, encodeId=2718138948284, content=<a href='/topic/show?id=8425519625e' target=_blank style='color:#2F92EE;'>#心衰风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=51962, encryptionId=8425519625e, topicName=心衰风险)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/4E6244DB7C1860858424437821E08291/100, createdBy=a6a52500039, createdName=ms3994565386320060, createdTime=Wed Aug 18 09:23:56 CST 2021, time=2021-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1563503, encodeId=c5c01563503c1, content=<a href='/topic/show?id=f69d864413' target=_blank style='color:#2F92EE;'>#HEART#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=47, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=8644, encryptionId=f69d864413, topicName=HEART)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=80d715270048, createdName=slcumt, createdTime=Wed Aug 18 09:23:56 CST 2021, time=2021-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1008516, encodeId=74b910085164d, content=有没有犯“死过的人,都喝过水吃过饭”的矛盾,尤其心衰病人主要在老年人,同时老年人的睡眠时间又不长。, beContent=null, objectType=article, channel=null, level=null, likeNumber=82, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://img.medsci.cn/20220207/ab38938022e64950bd2b04d641da58b7/ce41c87c9613416abed34525edc5988e.jpg, createdBy=71965399507, createdName=egbert喜子, createdTime=Tue Aug 17 00:28:49 CST 2021, time=2021-08-17, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1008410, encodeId=2d771008410c7, content=学习啦!谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=72, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLK1wzJZRTON4gxYUibhUyOypBwMibC4R7SsppicGhz5Ogoy0VVq4CWnqaD2Moeib8RWxI5lOiaVmnxpan/0, createdBy=c53f1730331, createdName=tanxingdoctor, createdTime=Mon Aug 16 19:10:58 CST 2021, time=2021-08-16, status=1, ipAttribution=)]
    2021-08-17 egbert喜子

    有没有犯“死过的人,都喝过水吃过饭”的矛盾,尤其心衰病人主要在老年人,同时老年人的睡眠时间又不长。

    0

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    2021-08-16 tanxingdoctor

    学习啦!谢谢

    0

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