J Eur Acad Dermatol Venereol:荟萃分析显示牙周炎可增加银屑病的发病风险

2016-11-27 MedSci MedSci原创

越来越多的研究发现牙周炎和全身性疾病之间存在关联。然而,关于牙周炎和牛皮癣之间关联的研究目前十分有限。本研究旨在对牙周炎与银屑病发病风险之间的关系做一系统回顾和荟萃分析。由两位研究者独立检索2016年7月之前已发表在MEDLINE和EMBASE数据库中的关于牛皮癣和牙周炎的相关文章。纳入标准:(1)病例对照和队列研究对比了伴或不伴牙周炎的患者银屑病的发病风险;(2)非牙周炎受试者作为队列研究的对照

越来越多的研究发现牙周炎和全身性疾病之间存在关联。然而,关于牙周炎和银屑病之间关联的研究目前十分有限。本研究旨在对牙周炎与银屑病发病风险之间的关系做一系统回顾和荟萃分析。

由两位研究者独立检索2016年7月之前已发表在MEDLINE和EMBASE数据库中的关于牛皮癣和牙周炎的相关文章。纳入标准:(1)病例对照和队列研究对比了伴或不伴牙周炎的患者银屑病的发病风险;(2)非牙周炎受试者作为队列研究的对照者,非银屑病受试者作为病例对照研究的对照组;(3)研究中使用了95%置信区间进行评估。提取每项研究的点估计值和标准差,并利用方差倒数法进行分析。

结果共纳入了两项队列研究和三项病例对照研究进行荟萃分析。与非牙周炎受试者相比,牙周炎患者的银屑病发病总风险比为1.55(95% CI,1.35-1.77)。统计学异质性明显,I2为18%。根据研究设计,亚组分析显示,队列研究中牙周炎患者总的RR为1.50(95% CI,1.37 - 1.64),病例对照研究中RR位2.33(95% CI,1.51 - 3.60),银屑病的发病风险显著升高。

总而言之,该系统回顾和荟萃分析显示,牙周炎患者患银屑病的风险显著升高。

原始出处:

Ungprasert P, Wijarnpreecha K, Wetter DA. Periodontitis and Risk of Psoriasis: A Systematic Review and Meta-analysis. J Eur Acad Dermatol Venereol. 2016 Nov 15.


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    2017-04-09 venlin
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    2017-05-26 lishizhe
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    2016-12-03 虈亣靌

    讲的好,分享了

    0

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    2016-11-30 zhixue

    全身健康从齿开始

    0

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    2016-11-30 顾小北大魔王

    太强大了?

    0

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    2016-11-27 Zephyro

    所以口腔与全身健康啊

    0

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    2016-11-27 186****0580(小山羊)

    了解了,分享了!

    0

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