2型糖尿病患者的胰岛素相关癌症风险

2016-10-27 生物谷 生物谷

根据本月21号在线发表在国际学术期刊Journal of Internal Medicine上的一项最新研究,2型糖尿病患者服用他汀药物能够抵消胰岛素相关癌症风险。在这项研究中,来自奥地利维也纳医科大学的Alexandra Kautzky-Willer和她的同事们对奥地利人群中2型糖尿病治疗,他汀药物使用与特定部位癌症之间存在的所有可能的关联进行了概括和描述,他们所使用的数据来自2006年到200


根据本月21号在线发表在国际学术期刊Journal of Internal Medicine上的一项最新研究,2型糖尿病患者服用他汀药物能够抵消胰岛素相关癌症风险。

在这项研究中,来自奥地利维也纳医科大学的Alexandra Kautzky-Willer和她的同事们对奥地利人群中2型糖尿病治疗,他汀药物使用与特定部位癌症之间存在的所有可能的关联进行了概括和描述,他们所使用的数据来自2006年到2007年住院治疗的1847051名病人的医疗数据。

经过分析之后研究人员发现对于接受胰岛素或胰岛素促分泌药物治疗的病人来说,结肠癌(只有男性),肝癌(只有男性),胰腺癌,肺癌(只有男性)和脑癌(只有男性)的风险增加高达9倍;而前列腺癌风险大大下降。非常重要的是,服用他汀药物的病人其癌症风险普遍下降,那些没有接受抗高血糖药物治疗的病人风险下降更加显著。这种保护作用对于胰岛素与胰腺癌,磺脲类药物或格列酮类药物与皮肤癌,二甲双胍与前列腺癌、子宫癌和非霍奇金淋巴瘤之间的风险关系改变最显著。

文章作者写道:“总的来说,我们的数据支持了高血糖症与癌症之间存在关联的假设。能够帮助减少胰岛素使用增加胰岛素敏感性的药物是更好的糖尿病治疗选择。”

原始出处:

Kautzky-Willer A, Thurner S, Klimek P. Use of statins offsets insulin-related cancer risk. J Intern Med. 2016 Oct 21. doi: 10.1111/joim.12567.

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    2017-03-01 baoya
  2. [GetPortalCommentsPageByObjectIdResponse(id=1749659, encodeId=52f81e49659fd, content=<a href='/topic/show?id=be7c8385345' target=_blank style='color:#2F92EE;'>#胰岛#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=83853, encryptionId=be7c8385345, topicName=胰岛)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a7a536274692, createdName=baoya, createdTime=Wed Mar 01 20:41:00 CST 2017, time=2017-03-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=153094, encodeId=77b115309455, content=他汀好东东, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTJUxfqEBLTrFZvMCToegPxv4CovnkibcroaO2d41HROFgTh9Acnhia4m6BiaRwLMpm8tC9yticL9WQ2lQ/132, createdBy=428e1975226, createdName=小靖儿, createdTime=Thu Nov 03 11:52:58 CST 2016, time=2016-11-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=152286, encodeId=68da1522864c, content=学习了,知道了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=75, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Mon Oct 31 00:58:50 CST 2016, time=2016-10-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1383263, encodeId=fa24138326363, content=<a href='/topic/show?id=196a1101f7' target=_blank style='color:#2F92EE;'>#2型糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1101, encryptionId=196a1101f7, topicName=2型糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=ec19483, createdName=aids213, createdTime=Sat Oct 29 08:41:00 CST 2016, time=2016-10-29, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1474085, encodeId=1e7614e408507, content=<a href='/topic/show?id=935fe6718e3' target=_blank style='color:#2F92EE;'>#糖尿病患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=76718, encryptionId=935fe6718e3, topicName=糖尿病患者)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a38f7243741, createdName=xue8604, createdTime=Sat Oct 29 08:41:00 CST 2016, time=2016-10-29, status=1, ipAttribution=)]
    2016-11-03 小靖儿

    他汀好东东

    0

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    2016-10-31 186****0580(小山羊)

    学习了,知道了!

    0

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