J Am Coll Cardiol:伴有心衰的肥胖患者接受减肥术治疗可显著降低其心衰加重的风险

2016-02-29 MedSci MedSci原创

J Am Coll Cardiol:伴有心衰的肥胖患者接受减肥术治疗可显著降低其心衰加重的风险肥胖和心脏衰竭(HF)是美国所面临的两种重要健康问题。虽然有研究表明肥胖和心衰的发病率之间存在关联,但是关于心衰患者减掉大部分体重后的效果却知之甚少。该项研究探究了减肥手术是否可以降低患者心衰加重的发病率。采用自我对照病例研究设计,纳入了伴有心衰的已接受减肥手术的肥胖患者,患者来自于加利福尼亚的急救部门(

肥胖和心脏衰竭(HF)是美国所面临的两种重要健康问题。虽然有研究表明肥胖和心衰的发病率之间存在关联,但是关于心衰患者减掉大部分体重后的效果却知之甚少。

该项研究探究了减肥手术是否可以降低患者心衰加重的发病率。

采用自我对照病例研究设计,纳入了伴有心衰的已接受减肥手术的肥胖患者,患者来自于加利福尼亚的急救部门(ED)和住院病人。主要结果为2005年到2011年患者因心衰而就诊于急诊科或接受住院治疗。采用条件Logistic回归分析连续12个月比较这期间患者就诊于急诊科或住院治疗的发生率,术前13个月至术前24个月作为基准期。

最后共纳入了524名接受减肥手术治疗的心衰患者。基准期,16.2%的患者因心衰加重而就诊于急诊科或接受住院治疗。在随后的12个月,未接受减肥术前,此人数比例基本不变(15.6%)。而接受减肥术后的12个月里,可以发现此比例明显降低(12%)。而且,在接受手术后的第13-24个月期间,此比例降低更多(9.9%)。相比之下,未接受减肥术治疗的心衰患者其心衰恶化的人数比例则无明显变化。

总而言之,我们的研究结果表明,减肥手术可降低肥胖心衰患者因心衰加重需要接受住院或急诊室评估的风险。

原始出处:

Yuichi J. Shimada, Yusuke Tsugawa, et al., Bariatric Surgery and Emergency Department Visits and Hospitalizations for Heart Failure Exacerbation : Population-Based, Self-Controlled Series. Journal of the American College of Cardiology, Volume 67, Issue 8, 1 March 2016, Pages 895–903.

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    2016-12-21 kksonne
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    2016-06-04 waiwai3030
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