JAMA SURGERY:急性阑尾炎患者更愿意选择手术还是抗生素治疗?

2018-01-12 MedSci MedSci原创

已有很多研究比较急性阑尾炎手术和非手术治疗的结果,但是这些研究都没有进行病人意愿的调查。JAMA SURGERY近期发表了一篇文章,分析急性阑尾炎患者更愿意选择手术治疗还是非手术治疗。

已有很多研究比较急性阑尾炎手术和非手术治疗的结果,但是这些研究都没有进行病人意愿的调查。JAMA SURGERY近期发表了一篇文章,分析急性阑尾炎患者更愿意选择手术治疗还是非手术治疗。

该研究包括网络调查和敏感性分析。网络调查时,1728例参与调查的受访者被要求想象他们自己或孩子患有急性阑尾炎,为他们提供腹腔镜和开腹阑尾切除手术以及仅进行抗生素治疗的信息,询问他们的选择。网络调查时间从2016年4月17日到2016年6月16日。敏感性分析时,220例受访者被给予相同的情景和选择。选择手术的受访者被询问是否有某种因素影响了他们的决定。这些受访者在2016年6月3日至2016年7月31日之间进行招募。主要的研究结果为治疗选择。研究结果发现,当自己患急性阑尾炎时,1482例受访者选择腹腔镜阑尾切除,84例受访者选择开腹切除,250例受访者选择仅接受抗生素治疗。受教育程度在大学以上,非西班牙裔白人,不认识之前住过院的人的受访者更倾向于选择抗生素对自己进行治疗,但如果是外科医生的话不会倾向于选择抗生素。220例参与敏感性分析的受访者分析表明,抗生素治疗失败率降低,而不是住院时间或抗生素治疗时间缩短,更容易吸引受访者选择抗生素。

文章最后认为,在治疗急性阑尾炎时,大部分患者会选择手术治疗,但也有一部分患者会选择非手术治疗。因此,从以病人为中心的观点看,在选择治疗方式时应与病人讨论。未来的研究应关注降低抗生素治疗失败率和复发率。

原始出处:
Alexis L.Hanson,Ross D.Crosby,et al.Patient Preferenced for Surgery or Antibiotics for the Treatment of Acute Appendicitis.JAMA SURGERY.January 2018 doi:10.1001/jamasurg.2017.5310

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    2018-10-25 chg121
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