J Periodontol:同一的个体种植体与天然牙周围的生物标志物和细菌

2017-08-16 MedSci MedSci原创

该横断面研究评估了种植体周围龈沟液(PICF)/牙龈沟液(GCF)中的细胞因子水平以及来自同一人群临床健康或患病位点的龈下/粘膜下菌斑的选择。

该横断面研究评估了种植体周围龈沟液(PICF)/牙龈沟液(GCF)中的细胞因子水平以及来自同一人群临床健康或患病位点的龈下/粘膜下菌斑的选择。

实验共有15位全身系统健康患者参与,有97例种植体/牙齿(58例种植体[19例健康,20例粘膜炎,19例种植体周围炎]和39例天然牙[19例健康,12例牙龈炎,8例牙周炎], 采用免疫分析法和实时荧光定量法检测。首先获得样品,然后记录探诊深度,临床附着水平,探查出血量,菌斑指数和角质化组织宽度。然后采用Wilcoxon,Mann-Whitney U进行数据分析,并对依赖性,独立性,以及混合依赖,独立样本和斯皮尔曼相关进行分析。

结果:健康种植体PICF样本中白细胞介素(IL)-1β水平明显高于健康牙齿GCF样本(P = 0.003),牙龈炎组核因子κB配体(sRANKL)可溶性受体活化剂的浓度明显高于粘膜炎组(P = 0.004)。生物标志物水平在种植体周围炎和牙周炎组相似(P> 0.05)。健康种植体组的放线杆菌和口腔链球菌水平均显着高于健康牙齿(P <0.05)。粘膜炎组中间普雷沃菌和齿垢密螺旋体(Td)水平低于牙龈炎组(P <0.05)。牙周炎组中间普雷沃菌和口腔链球菌水平明显高(P <0.05),种植体周围炎组齿垢密螺旋体水平较高(P <0.05)。

种植体和天然牙有许多相似之处,但重要的是,同一人群中生物标志物水平(IL-1β和sRANKL)与种植体周围和牙周位点的细菌种类有一些差异,表明两者类似的致病机制。

原始出处:

Onder Gürlek, Pinar Gümüs, Christopher J. Nile, et al. Biomarkers and Bacteria Around Implants and Natural Teeth in the Same Individuals. Journal of periodontology. 2017 August. doi: 10.1902/ jop.2017.1607


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    2018-07-30 huangdf
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  5. 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  6. 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  8. 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createdBy=f06c33759375, createdName=feather89, createdTime=Mon Feb 05 14:03:00 CST 2018, time=2018-02-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1841079, encodeId=5a4a18410e9fb, content=<a href='/topic/show?id=18bf61953d3' target=_blank style='color:#2F92EE;'>#标志物#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=61953, encryptionId=18bf61953d3, topicName=标志物)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=6ab940, createdName=hukaixun, createdTime=Thu Oct 19 14:03:00 CST 2017, time=2017-10-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1343722, encodeId=f39a1343e2243, content=<a href='/topic/show?id=d512e47853f' target=_blank style='color:#2F92EE;'>#种植体#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, 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createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Fri Aug 18 03:03:00 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234168, encodeId=b51b234168de, content=学习了,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Wed Aug 16 21:34:38 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234113, encodeId=8c8723411339, content=学习了,谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Wed Aug 16 13:24:14 CST 2017, time=2017-08-16, status=1, ipAttribution=)]
    2017-08-16 1e0f8808m18(暂无匿称)

    学习了,谢谢分享。

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=1701865, encodeId=24cd1e01865e3, content=<a href='/topic/show?id=04b9e4784aa' target=_blank style='color:#2F92EE;'>#种植#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=74784, encryptionId=04b9e4784aa, topicName=种植)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=47e130405619, createdName=huangdf, createdTime=Mon Jul 30 05:03:00 CST 2018, time=2018-07-30, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1726649, encodeId=69421e2664940, content=<a href='/topic/show?id=986913980dd' target=_blank style='color:#2F92EE;'>#PE#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=29, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13980, encryptionId=986913980dd, topicName=PE)], attachment=null, authenticateStatus=null, createdAvatar=null, 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createdBy=63db15173977, createdName=zhu_jun9842, createdTime=Fri Aug 18 03:03:00 CST 2017, time=2017-08-18, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234168, encodeId=b51b234168de, content=学习了,谢谢分享。, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=60791943465, createdName=1e0f8808m18(暂无匿称), createdTime=Wed Aug 16 21:34:38 CST 2017, time=2017-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=234113, encodeId=8c8723411339, content=学习了,谢谢。, beContent=null, objectType=article, channel=null, level=null, likeNumber=44, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/xkvRjYnJzzRJ2R0y7VhicibvkjPWHjIMmu4ZpKnE9cWAu4lVicS3uDUCfF4M4JWvrkrYfpb2KehPV0Ee29tPqyPEebBUibiaKhnvD/0, createdBy=f8412001184, createdName=惠映实验室, createdTime=Wed Aug 16 13:24:14 CST 2017, time=2017-08-16, status=1, ipAttribution=)]
    2017-08-16 惠映实验室

    学习了,谢谢。

    0

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