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NeuroImage:clinnical:颞叶癫痫手术后，对侧海马与双侧 MPFC 和 SFG 之间的 FC 增加可能与术后功能重塑有关

2021-06-26 MedSci原创 MedSci原创

颞叶癫痫海马功能连接术后功能重塑
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成功的 ATL 可能不会导致对侧海马体的明显结构重组。手术操作可能导致对侧海马体的 FC 一过性减少。对侧海马与双侧 MPFC 和 SFG 之间的 FC 增加可能与术后功能重塑有关。

颞叶内侧癫痫(mTLE)是成人最常见的难治性癫痫。颞叶结构，尤其是海马，在癫痫活动的产生和传播中起着关键作用。海马硬化(HS)是难治性mTLE最常见的病理。前颞叶切除术(ATL)是治疗难治性mTLE的一种成熟的治疗方法，可使癫痫的无发作率达到60-70%。然而，癫痫手术仍未得到充分利用，从最初诊断到手术平均延迟20年。此外，约30-40%的患者术后继续癫痫发作，即使有明显的单侧HS证据。到目前为止，颞叶癫痫手术后的癫痫发作和认知结果仍很难预测。 NeuroImage:clinnical杂志刊发了Li W等人的研究文章，探讨前颞叶切除术（ATL）后无癫痫发作的单侧颞叶内侧癫痫（mTLE）患者对侧海马的结构和功能重组。 该团队之前研究了mTLE患者低频波动(ALFF)改变的纵向扩散和振幅，并揭示了全脑水平的术后结构和功能重组。这次研究聚焦于mTLE的关键结构，并评估了ATL后至少两年无癫痫发作的的mTLE患者对侧海马GMV和FC的纵向变化。 由于海马硬化(hippocampalsclerosis, HS)是mTLE中最常见的病理，该研究只纳入了HS或MRI正常的mTLE患者。术前GMV和F

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    2022-01-28 yige2004

    #癫痫手术#

    0

  2. [GetPortalCommentsPageByObjectIdResponse(id=1957915, encodeId=1da4195e915e7, content=<a href='/topic/show?id=dcf7e15748b' target=_blank style='color:#2F92EE;'>#癫痫手术#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=55, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71574, encryptionId=dcf7e15748b, topicName=癫痫手术)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=66962500501, createdName=yige2004, createdTime=Fri Jan 28 07:37:46 CST 2022, time=2022-01-28, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2054787, encodeId=d94e2054e8795, content=<a href='/topic/show?id=88bc141167c' target=_blank style='color:#2F92EE;'>#PFC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=14116, encryptionId=88bc141167c, topicName=PFC)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLx96cCLjNYsHar1XErTVibOydfEC9iaYgrXp3SicXwntSAEDeQAlM2vLqTfm6oPORxaib3UIgyHQJJ7A/132, createdBy=36f02500138, createdName=ms6980045490879608, createdTime=Sun Aug 22 10:37:46 CST 2021, time=2021-08-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1512248, encodeId=a6f9151224884, content=<a href='/topic/show?id=488f100e806b' target=_blank style='color:#2F92EE;'>#颞叶癫痫#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100780, encryptionId=488f100e806b, topicName=颞叶癫痫)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=d4f010449023, createdName=ms3994565386320060, createdTime=Sun Jun 27 16:37:46 CST 2021, time=2021-06-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1522475, encodeId=2cd015224e519, content=<a href='/topic/show?id=46223e39897' target=_blank style='color:#2F92EE;'>#双侧#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=37398, encryptionId=46223e39897, topicName=双侧)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=741b11453403, createdName=wangbingxhy, createdTime=Sun Jun 27 16:37:46 CST 2021, time=2021-06-27, status=1, ipAttribution=)]
    2021-08-22 ms6980045490879608

    #PFC#

    0

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    2021-06-27 ms3994565386320060

    #颞叶癫痫#

    0

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    2021-06-27 wangbingxhy

    #双侧#

    0

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