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JNCI：摄入高脂肪饮食与特定类型的乳腺癌风险增加有关联

2014-04-10 eurekalert Eurekalert中文版

高脂肪乳腺癌
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发表在4月9日出版的《美国国立癌症研究所杂志》（Journal of the National Cancer Institute）上的一项新研究表明，总脂肪和饱和脂肪摄入量高与雌激素受体阳性和孕激素受体阳性（ER+PR+）乳腺癌（BC）以及2型人类上皮生长因子受体阴性（HER2-）疾病的更高风险有关联。已发表的关于高脂肪摄入量与乳腺癌风险之间相关联的流行病学和病例对照研究数据一直存在着冲突，这可能

发表在4月9日出版的《美国国立癌症研究所杂志》（Journal of the National Cancer Institute）上的一项新研究表明，总脂肪和饱和脂肪摄入量高与雌激素受体阳性和孕激素受体阳性（ER+PR+）乳腺癌（BC）以及2型人类上皮生长因子受体阴性（HER2-）疾病的更高风险有关联。

已发表的关于高脂肪摄入量与乳腺癌风险之间相关联的流行病学和病例对照研究数据一直存在着冲突，这可能是因为获取脂肪摄入的准确信息的困难很多，也可能是由这些参与研究的群组所生活的特定地理区域内有限的摄食异质性造成的。此外，乳腺癌如今根据雌激素受体（ER）、孕激素受体（PR）以及2型人类上皮生长因子（HER2）的表达状态而被临床归类为几个亚型，每一个亚型有自己的预后和一组风险因子，这也可能造成了已发表的针对这种关联的报告的不一致性。

意大利米兰国家癌症研究中心IRCCS基金会预防与预测医学系流行病学与预防组的Sabina Sieri博士及其同事对EPIC研究随访了11.5年的10062名乳腺癌患者的数据进行了前瞻性分析。EPIC群组由生活在10个欧洲国家的33万7327名女性组成，就地理相关饮食脂肪摄入模式和分子亚型而言，这都是一个具有异质性的群组。为了纠正这种饮食问卷调查数据的测量误差，研究人员用标准化的24小时饮食回忆访问校准了摄食数据，对这个群组的8%的随机样本进行了这种访问。Cox比例风险建模纳入了各种已知的风险因素作为协变量。

这组作者报告说，总脂肪和饱和脂肪摄入量高与雌激素受体阳性（ER+）和孕激素受体阳性（PR+）乳腺癌（BC）的风险增加有关联。饱和脂肪摄入量高也与2型人类上皮生长因子受体阴性（HER2-）疾病的风险增加有关联。这组作者得出结论说，“高脂肪饮食增加乳腺癌风险，最显著的是，高饱和脂肪摄入增加受体阳性疾病的风险，这提示饱和脂肪与受体阳性乳腺癌的病因有关。”


原始出处：

Sabina Sieri, Paolo Chiodini, Claudia Agnoli, Valeria Pala, Franco Berrino, Antonia Trichopoulou, Vassiliki Benetou, Effie Vasilopoulou, María-José Sánchez, Maria-Dolores Chirlaque, Pilar Amiano, J. Ramón Quirós, Eva Ardanaz, Genevieve Buckland, Giovanna Masala, Salvatore Panico, Sara Grioni, Carlotta Sacerdote, Rosario Tumino, Marie-Christine Boutron-Ruault, Françoise Clavel-Chapelon, Guy Fagherazzi, Petra H. M. Peeters, Carla H. van Gils, H. Bas Bueno-de-Mesquita, Henk J. van Kranen, Timothy J. Key, Ruth C. Travis, Kay Tee Khaw, Nicholas J. Wareham, Rudolf Kaaks, Annekatrin Lukanova, Heiner Boeing, Madlen Schütze, Emily Sonestedt, Elisabeth Wirfält, Malin Sund, Anne Andersson, Veronique Chajes, Sabina Rinaldi, Isabelle Romieu, Elisabete Weiderpass, Guri Skeie, Engeset Dagrun, Anne Tjønneland, Jytte Halkjær, Kim Overvard, Melissa A. Merritt, David Cox, Elio Riboli and Vittorio Krogh.Dietary Fat Intake and Development of Specific Breast Cancer Subtypes.J Natl Cancer Inst April 9, 2014  doi: 10.1093/jnci/dju068


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    2015-02-27 xiaoai5777

    不错的文章，学习了

    0

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    2014-12-27 sjq027

    #癌风险#

    0

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    2014-07-08 ms6829001416292975

    #特定类型#

    0

  4. [GetPortalCommentsPageByObjectIdResponse(id=17105, encodeId=5c491e1055a, content=不错的文章，学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36a81612921, createdName=xiaoai5777, createdTime=Fri Feb 27 15:36:00 CST 2015, time=2015-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061429, encodeId=338e2061429a2, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Sat Dec 27 03:36:00 CST 2014, time=2014-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798027, encodeId=992e1e98027af, content=<a href='/topic/show?id=26c56e923f7' target=_blank style='color:#2F92EE;'>#特定类型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67923, encryptionId=26c56e923f7, topicName=特定类型)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/F82CC4A89F97BD21D3DDB7AD5F2AD09D/100, createdBy=52952500022, createdName=ms6829001416292975, createdTime=Tue Jul 08 19:36:00 CST 2014, time=2014-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1770221, encodeId=13061e7022133, content=<a href='/topic/show?id=df9c23e868a' target=_blank style='color:#2F92EE;'>#乳腺癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23786, encryptionId=df9c23e868a, topicName=乳腺癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9538161180, createdName=gaoxiaoe, createdTime=Thu Feb 19 15:36:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1694446, encodeId=efc5169444644, content=<a href='/topic/show?id=e73610261912' target=_blank style='color:#2F92EE;'>#高脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102619, encryptionId=e73610261912, topicName=高脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=831a29654518, createdName=jinweidong, createdTime=Wed Aug 20 07:36:00 CST 2014, time=2014-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1933671, encodeId=118219336e182, content=<a href='/topic/show?id=71a81258504' target=_blank style='color:#2F92EE;'>#NCI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12585, encryptionId=71a81258504, topicName=NCI)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ee7414, createdName=lanyan20020086, createdTime=Fri Mar 13 12:36:00 CST 2015, time=2015-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1389079, encodeId=76ed13890e96f, content=<a href='/topic/show?id=d45c10262260' target=_blank style='color:#2F92EE;'>#高脂肪饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102622, encryptionId=d45c10262260, topicName=高脂肪饮食)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Sat Apr 12 00:36:00 CST 2014, time=2014-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574540, encodeId=0ef115e45403e, content=<a href='/topic/show?id=9b56102616bb' target=_blank style='color:#2F92EE;'>#高脂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102616, encryptionId=9b56102616bb, topicName=高脂)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3b716021149, createdName=pcw111, createdTime=Sat Apr 12 00:36:00 CST 2014, time=2014-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8926, encodeId=f10e892601, content=饮食与肿瘤相关，非偶然！这可以比较亚洲与欧美人群的饮食习惯差异，肿瘤谱的差异是否有关联，也是有意思的, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=小小, createdTime=Thu Apr 10 11:06:00 CST 2014, time=2014-04-10, status=1, ipAttribution=)]
    2015-02-19 gaoxiaoe

    #乳腺癌风险#

    0

  5. [GetPortalCommentsPageByObjectIdResponse(id=17105, encodeId=5c491e1055a, content=不错的文章，学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36a81612921, createdName=xiaoai5777, createdTime=Fri Feb 27 15:36:00 CST 2015, time=2015-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061429, encodeId=338e2061429a2, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Sat Dec 27 03:36:00 CST 2014, time=2014-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798027, encodeId=992e1e98027af, content=<a href='/topic/show?id=26c56e923f7' target=_blank style='color:#2F92EE;'>#特定类型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67923, encryptionId=26c56e923f7, topicName=特定类型)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/F82CC4A89F97BD21D3DDB7AD5F2AD09D/100, createdBy=52952500022, createdName=ms6829001416292975, createdTime=Tue Jul 08 19:36:00 CST 2014, time=2014-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1770221, encodeId=13061e7022133, content=<a href='/topic/show?id=df9c23e868a' target=_blank style='color:#2F92EE;'>#乳腺癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23786, encryptionId=df9c23e868a, topicName=乳腺癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9538161180, createdName=gaoxiaoe, createdTime=Thu Feb 19 15:36:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1694446, encodeId=efc5169444644, content=<a href='/topic/show?id=e73610261912' target=_blank style='color:#2F92EE;'>#高脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102619, encryptionId=e73610261912, topicName=高脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=831a29654518, createdName=jinweidong, createdTime=Wed Aug 20 07:36:00 CST 2014, time=2014-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1933671, encodeId=118219336e182, content=<a href='/topic/show?id=71a81258504' target=_blank style='color:#2F92EE;'>#NCI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12585, encryptionId=71a81258504, topicName=NCI)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ee7414, createdName=lanyan20020086, createdTime=Fri Mar 13 12:36:00 CST 2015, time=2015-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1389079, encodeId=76ed13890e96f, content=<a href='/topic/show?id=d45c10262260' target=_blank style='color:#2F92EE;'>#高脂肪饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102622, encryptionId=d45c10262260, topicName=高脂肪饮食)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Sat Apr 12 00:36:00 CST 2014, time=2014-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574540, encodeId=0ef115e45403e, content=<a href='/topic/show?id=9b56102616bb' target=_blank style='color:#2F92EE;'>#高脂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102616, encryptionId=9b56102616bb, topicName=高脂)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3b716021149, createdName=pcw111, createdTime=Sat Apr 12 00:36:00 CST 2014, time=2014-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8926, encodeId=f10e892601, content=饮食与肿瘤相关，非偶然！这可以比较亚洲与欧美人群的饮食习惯差异，肿瘤谱的差异是否有关联，也是有意思的, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=小小, createdTime=Thu Apr 10 11:06:00 CST 2014, time=2014-04-10, status=1, ipAttribution=)]
    2014-08-20 jinweidong

    #高脂肪#

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=17105, encodeId=5c491e1055a, content=不错的文章，学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36a81612921, createdName=xiaoai5777, createdTime=Fri Feb 27 15:36:00 CST 2015, time=2015-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061429, encodeId=338e2061429a2, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Sat Dec 27 03:36:00 CST 2014, time=2014-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798027, encodeId=992e1e98027af, content=<a href='/topic/show?id=26c56e923f7' target=_blank style='color:#2F92EE;'>#特定类型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67923, encryptionId=26c56e923f7, topicName=特定类型)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/F82CC4A89F97BD21D3DDB7AD5F2AD09D/100, createdBy=52952500022, createdName=ms6829001416292975, createdTime=Tue Jul 08 19:36:00 CST 2014, time=2014-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1770221, encodeId=13061e7022133, content=<a href='/topic/show?id=df9c23e868a' target=_blank style='color:#2F92EE;'>#乳腺癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23786, encryptionId=df9c23e868a, topicName=乳腺癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9538161180, createdName=gaoxiaoe, createdTime=Thu Feb 19 15:36:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1694446, encodeId=efc5169444644, content=<a href='/topic/show?id=e73610261912' target=_blank style='color:#2F92EE;'>#高脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102619, encryptionId=e73610261912, topicName=高脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=831a29654518, createdName=jinweidong, createdTime=Wed Aug 20 07:36:00 CST 2014, time=2014-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1933671, encodeId=118219336e182, content=<a href='/topic/show?id=71a81258504' target=_blank style='color:#2F92EE;'>#NCI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12585, encryptionId=71a81258504, topicName=NCI)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ee7414, createdName=lanyan20020086, createdTime=Fri Mar 13 12:36:00 CST 2015, time=2015-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1389079, encodeId=76ed13890e96f, content=<a href='/topic/show?id=d45c10262260' target=_blank style='color:#2F92EE;'>#高脂肪饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102622, encryptionId=d45c10262260, topicName=高脂肪饮食)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Sat Apr 12 00:36:00 CST 2014, time=2014-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574540, encodeId=0ef115e45403e, content=<a href='/topic/show?id=9b56102616bb' target=_blank style='color:#2F92EE;'>#高脂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102616, encryptionId=9b56102616bb, topicName=高脂)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3b716021149, createdName=pcw111, createdTime=Sat Apr 12 00:36:00 CST 2014, time=2014-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8926, encodeId=f10e892601, content=饮食与肿瘤相关，非偶然！这可以比较亚洲与欧美人群的饮食习惯差异，肿瘤谱的差异是否有关联，也是有意思的, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=小小, createdTime=Thu Apr 10 11:06:00 CST 2014, time=2014-04-10, status=1, ipAttribution=)]
    2015-03-13 lanyan20020086

    #NCI#

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=17105, encodeId=5c491e1055a, content=不错的文章，学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36a81612921, createdName=xiaoai5777, createdTime=Fri Feb 27 15:36:00 CST 2015, time=2015-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061429, encodeId=338e2061429a2, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Sat Dec 27 03:36:00 CST 2014, time=2014-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798027, encodeId=992e1e98027af, content=<a href='/topic/show?id=26c56e923f7' target=_blank style='color:#2F92EE;'>#特定类型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67923, encryptionId=26c56e923f7, topicName=特定类型)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/F82CC4A89F97BD21D3DDB7AD5F2AD09D/100, createdBy=52952500022, createdName=ms6829001416292975, createdTime=Tue Jul 08 19:36:00 CST 2014, time=2014-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1770221, encodeId=13061e7022133, content=<a href='/topic/show?id=df9c23e868a' target=_blank style='color:#2F92EE;'>#乳腺癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23786, encryptionId=df9c23e868a, topicName=乳腺癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9538161180, createdName=gaoxiaoe, createdTime=Thu Feb 19 15:36:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1694446, encodeId=efc5169444644, content=<a href='/topic/show?id=e73610261912' target=_blank style='color:#2F92EE;'>#高脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102619, encryptionId=e73610261912, topicName=高脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=831a29654518, createdName=jinweidong, createdTime=Wed Aug 20 07:36:00 CST 2014, time=2014-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1933671, encodeId=118219336e182, content=<a href='/topic/show?id=71a81258504' target=_blank style='color:#2F92EE;'>#NCI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12585, encryptionId=71a81258504, topicName=NCI)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ee7414, createdName=lanyan20020086, createdTime=Fri Mar 13 12:36:00 CST 2015, time=2015-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1389079, encodeId=76ed13890e96f, content=<a href='/topic/show?id=d45c10262260' target=_blank style='color:#2F92EE;'>#高脂肪饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102622, encryptionId=d45c10262260, topicName=高脂肪饮食)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Sat Apr 12 00:36:00 CST 2014, time=2014-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574540, encodeId=0ef115e45403e, content=<a href='/topic/show?id=9b56102616bb' target=_blank style='color:#2F92EE;'>#高脂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102616, encryptionId=9b56102616bb, topicName=高脂)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3b716021149, createdName=pcw111, createdTime=Sat Apr 12 00:36:00 CST 2014, time=2014-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8926, encodeId=f10e892601, content=饮食与肿瘤相关，非偶然！这可以比较亚洲与欧美人群的饮食习惯差异，肿瘤谱的差异是否有关联，也是有意思的, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=小小, createdTime=Thu Apr 10 11:06:00 CST 2014, time=2014-04-10, status=1, ipAttribution=)]
    2014-04-12 膀胱癌

    #高脂肪饮食#

    0

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    2014-04-12 pcw111

    #高脂#

    0

  9. [GetPortalCommentsPageByObjectIdResponse(id=17105, encodeId=5c491e1055a, content=不错的文章，学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=100, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=36a81612921, createdName=xiaoai5777, createdTime=Fri Feb 27 15:36:00 CST 2015, time=2015-02-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2061429, encodeId=338e2061429a2, content=<a href='/topic/show?id=e6e1e15509f' target=_blank style='color:#2F92EE;'>#癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=71550, encryptionId=e6e1e15509f, topicName=癌风险)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d58a435, createdName=sjq027, createdTime=Sat Dec 27 03:36:00 CST 2014, time=2014-12-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1798027, encodeId=992e1e98027af, content=<a href='/topic/show?id=26c56e923f7' target=_blank style='color:#2F92EE;'>#特定类型#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=52, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67923, encryptionId=26c56e923f7, topicName=特定类型)], attachment=null, authenticateStatus=null, createdAvatar=https://thirdqq.qlogo.cn/qqapp/1103841572/F82CC4A89F97BD21D3DDB7AD5F2AD09D/100, createdBy=52952500022, createdName=ms6829001416292975, createdTime=Tue Jul 08 19:36:00 CST 2014, time=2014-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1770221, encodeId=13061e7022133, content=<a href='/topic/show?id=df9c23e868a' target=_blank style='color:#2F92EE;'>#乳腺癌风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=45, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=23786, encryptionId=df9c23e868a, topicName=乳腺癌风险)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=4a9538161180, createdName=gaoxiaoe, createdTime=Thu Feb 19 15:36:00 CST 2015, time=2015-02-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1694446, encodeId=efc5169444644, content=<a href='/topic/show?id=e73610261912' target=_blank style='color:#2F92EE;'>#高脂肪#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102619, encryptionId=e73610261912, topicName=高脂肪)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=831a29654518, createdName=jinweidong, createdTime=Wed Aug 20 07:36:00 CST 2014, time=2014-08-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1933671, encodeId=118219336e182, content=<a href='/topic/show?id=71a81258504' target=_blank style='color:#2F92EE;'>#NCI#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12585, encryptionId=71a81258504, topicName=NCI)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=0ee7414, createdName=lanyan20020086, createdTime=Fri Mar 13 12:36:00 CST 2015, time=2015-03-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1389079, encodeId=76ed13890e96f, content=<a href='/topic/show?id=d45c10262260' target=_blank style='color:#2F92EE;'>#高脂肪饮食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=31, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102622, encryptionId=d45c10262260, topicName=高脂肪饮食)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/1103841572/C2EFD5CFB07FE291138AD4FD0C98E3DE/100, createdBy=e3d52500031, createdName=膀胱癌, createdTime=Sat Apr 12 00:36:00 CST 2014, time=2014-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1574540, encodeId=0ef115e45403e, content=<a href='/topic/show?id=9b56102616bb' target=_blank style='color:#2F92EE;'>#高脂#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=33, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=102616, encryptionId=9b56102616bb, topicName=高脂)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=c3b716021149, createdName=pcw111, createdTime=Sat Apr 12 00:36:00 CST 2014, time=2014-04-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=8926, encodeId=f10e892601, content=饮食与肿瘤相关，非偶然！这可以比较亚洲与欧美人群的饮食习惯差异，肿瘤谱的差异是否有关联，也是有意思的, beContent=null, objectType=article, channel=null, level=null, likeNumber=146, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=小小, createdTime=Thu Apr 10 11:06:00 CST 2014, time=2014-04-10, status=1, ipAttribution=)]
    2014-04-10 小小

    饮食与肿瘤相关，非偶然！这可以比较亚洲与欧美人群的饮食习惯差异，肿瘤谱的差异是否有关联，也是有意思的

    0