Diabetes Care:外分泌胰腺糖尿病的临床特征

2017-09-03 MedSci MedSci原创

近期,一项发表在杂志Diabetes Care上的研究描述了胰腺疾病后糖尿病的发病率,评估了这些患者如何被临床医生分类,并比较了1型和2型糖尿病的临床特征。此项研究自2005年1月1日至2016年3月31日期间,检索了英国初级保健记录(n = 2,360,631)中成人糖尿病。研究者们检查了在糖尿病诊断之前,有和无胰腺疾病患者的人口统计学,糖尿病分类,血糖控制和胰岛素使用(分类为急性胰腺炎或慢性胰

近期,一项发表在杂志Diabetes Care上的研究描述了胰腺疾病后糖尿病的发病率,评估了这些患者如何被临床医生分类,并比较了1型和2型糖尿病临床特征。


此项研究自2005年1月1日至2016年3月31日期间,检索了英国初级保健记录(n = 2,360,631)中成人糖尿病。研究者们检查了在糖尿病诊断之前,有和无胰腺疾病患者的人口统计学,糖尿病分类,血糖控制和胰岛素使用(分类为急性胰腺炎或慢性胰腺疾病)。使用回归分析评估血糖控制不良(HbA1c≥7%[53 mmol / mol])和胰岛素需求的潜在危险因素。

最终,此项研究确定了31,789例成人新发病糖尿病。胰腺疾病后的发生糖尿病者(每10万人年为2.59 [95%CI 2.38-2.81])比1型糖尿病(1.64 [1.47-1.82]; P <0.001)更为常见。胰腺疾病后的559例糖尿病大多被分类为2型糖尿病(87.8%),并且为外分泌胰腺糖尿病者十分罕见(2.7%)。

胰腺疾病后诊断为糖尿病的中位年龄为59岁,体重指数为29.2kg/m2。与2型糖尿病相比,胰腺疾病后的糖尿病与血糖控制不佳(调整后的OR值,1.7 [1.3-2.2]; P <0.001)。5年内2型糖尿病患者胰岛素使用量为4.1%(3.8-4.4),急性胰腺炎后糖尿病者为20.9%(14.6-28.9),慢性胰腺疾病后糖尿病者为45.8%(34.2-57.9)。

此项研究表明:外分泌胰腺的糖尿病经常被认为2型糖尿病,但是其血糖控制较差,对胰岛素的需求显着增加。

原始出处:
Woodmansey C, McGovern AP, et al. Incidence, Demographics, and Clinical Characteristics of Diabetes of the Exocrine Pancreas (Type 3c): A Retrospective Cohort Study. Diabetes Care. 2017 Aug 31. pii: dc170542. doi: 10.2337/dc17-0542. 

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    2018-05-16 gwc392
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likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhRvIvBCic3jbz4PVDcMREDl6iaWw7opPo99JEXWc0tmIrGaXGPP0y58DKDiajZfV2qR3qXdCgwIyhVq/0, createdBy=d71a1955931, createdName=QFXL123456, createdTime=Wed Sep 06 23:19:12 CST 2017, time=2017-09-06, status=1, ipAttribution=)]
    2017-09-21 1e1263e3m20(暂无匿称)

    文章不错涨知识了

    0

  7. 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topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Thu Apr 19 00:47:00 CST 2018, time=2018-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1842868, encodeId=35831842868b7, content=<a href='/topic/show?id=112222886b8' target=_blank style='color:#2F92EE;'>#临床特征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=32, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=22886, encryptionId=112222886b8, topicName=临床特征)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=yeye5224612, createdTime=Sun May 20 00:47:00 CST 2018, time=2018-05-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=246348, encodeId=0a1a246348ff, content=文章不错涨知识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=73, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84e21956153, createdName=1e1263e3m20(暂无匿称), createdTime=Thu Sep 21 15:17:05 CST 2017, time=2017-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242608, encodeId=c80a242608b7, content=认真学习.把间接经验应用到临床实践中去.然后再总结出新思路.给点赞啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30251637888, createdName=lietome15, createdTime=Sun Sep 10 20:18:48 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242468, encodeId=9d6324246809, content=文章不错.值得分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 10 08:54:18 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241415, encodeId=c0b824141563, content=文章很好.赞赞赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Sep 07 09:37:35 CST 2017, time=2017-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241189, encodeId=2fac2411897d, content=学习了.谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhRvIvBCic3jbz4PVDcMREDl6iaWw7opPo99JEXWc0tmIrGaXGPP0y58DKDiajZfV2qR3qXdCgwIyhVq/0, createdBy=d71a1955931, createdName=QFXL123456, createdTime=Wed Sep 06 23:19:12 CST 2017, time=2017-09-06, status=1, ipAttribution=)]
    2017-09-10 lietome15

    认真学习.把间接经验应用到临床实践中去.然后再总结出新思路.给点赞啦

    0

  8. 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replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=84e21956153, createdName=1e1263e3m20(暂无匿称), createdTime=Thu Sep 21 15:17:05 CST 2017, time=2017-09-21, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242608, encodeId=c80a242608b7, content=认真学习.把间接经验应用到临床实践中去.然后再总结出新思路.给点赞啦, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=30251637888, createdName=lietome15, createdTime=Sun Sep 10 20:18:48 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=242468, encodeId=9d6324246809, content=文章不错.值得分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 10 08:54:18 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241415, encodeId=c0b824141563, content=文章很好.赞赞赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Sep 07 09:37:35 CST 2017, time=2017-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241189, encodeId=2fac2411897d, content=学习了.谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhRvIvBCic3jbz4PVDcMREDl6iaWw7opPo99JEXWc0tmIrGaXGPP0y58DKDiajZfV2qR3qXdCgwIyhVq/0, createdBy=d71a1955931, createdName=QFXL123456, createdTime=Wed Sep 06 23:19:12 CST 2017, time=2017-09-06, status=1, ipAttribution=)]
    2017-09-10 1e10c84am36(暂无匿称)

    文章不错.值得分享

    0

  9. 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createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 10 08:54:18 CST 2017, time=2017-09-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241415, encodeId=c0b824141563, content=文章很好.赞赞赞, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Thu Sep 07 09:37:35 CST 2017, time=2017-09-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=241189, encodeId=2fac2411897d, content=学习了.谢谢!, beContent=null, objectType=article, channel=null, level=null, likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhRvIvBCic3jbz4PVDcMREDl6iaWw7opPo99JEXWc0tmIrGaXGPP0y58DKDiajZfV2qR3qXdCgwIyhVq/0, createdBy=d71a1955931, createdName=QFXL123456, createdTime=Wed Sep 06 23:19:12 CST 2017, time=2017-09-06, status=1, ipAttribution=)]
    2017-09-07 1e10c84am36(暂无匿称)

    文章很好.赞赞赞

    0

  10. 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likeNumber=62, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/icyLhIGqru6gIknBJqfuPhRvIvBCic3jbz4PVDcMREDl6iaWw7opPo99JEXWc0tmIrGaXGPP0y58DKDiajZfV2qR3qXdCgwIyhVq/0, createdBy=d71a1955931, createdName=QFXL123456, createdTime=Wed Sep 06 23:19:12 CST 2017, time=2017-09-06, status=1, ipAttribution=)]
    2017-09-06 QFXL123456

    学习了.谢谢!

    0