Plos One:性别差异是否影响急性心肌梗死的长期死亡率呢?

2017-10-22 MedSci MedSci原创

在急性心肌梗死(AMI)中幸存的女性患者死亡率超过男性。因此,有学者已经提出了性别在年龄、心血管危险因素和血运重建治疗之间的差异中可能是其中的一个原因。近期,一项发表在杂志Plos One上的研究选择了在相关风险因素相似的女性和男性患者,系统地比较了性别特异性的风险。此项研究调查评估了ISAR-RISK和ART研究的数据。受试患者在1996年至2005年期间入组,在入组前4周内均患有AMI。受试的

在急性心肌梗死(AMI)中幸存的女性患者死亡率超过男性。因此,有学者已经提出了性别在年龄、心血管危险因素和血运重建治疗之间的差异中可能是其中的一个原因。近期,一项发表在杂志Plos One上的研究选择了在相关风险因素相似的女性和男性患者,系统地比较了性别特异性的风险。此项研究调查评估了ISAR-RISK和ART研究的数据。受试患者在1996年至2005年期间入组,在入组前4周内均患有AMI。受试的不同性别的患者具有1:1当量的年龄,此前的AMI史,存在窦性心律,高血压,糖尿病,吸烟史,左心室射血分数(LVEF)和血运重建治疗。在整个研究队列和匹配队列中,对不同性别组受试者之间的生存时间进行了比较。此项研究结果显示:在3840例连续的AMI幸存者中,994例(25.9%)为女性,2846例(74.1%)为男性。女性年龄较大,经常发生高血压和糖尿病。在整个队列中,女性死亡率增加,与男性相比,危险比(HR)为1.54(p <0.0001)。匹配的队列中每个性别组有802名患者,并显示出女性生存率较低的趋势(女性HR为1.14;p = 0.359)。然而,在发生AMI(HR = 1.61

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    2017-10-23 2227437833_79976374

    很好很好很好

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    2017-10-23 雅文博武

    学习了很多先进的医疗技术

    0

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    2017-10-22 天涯183

    非常好的文章.学习了

    0

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    2017-10-22 131****1460

    学习了受益匪浅

    0

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    2017-10-22 清风拂面

    很好的文章.谢谢分享

    0

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    2017-10-22 中医痴

    不错的.学习了.谢谢分享!

    0

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