PLoS Negl Trop Dis:确定沙眼传播过程中的核心群体

2018-10-27 MedSci MedSci原创

加州大学旧金山分校的Lietman TM近日在PLoS Negl Trop Dis杂志上发表了一篇文章,他们通过建立模型,来确定沙眼传播过程中的核心群体。

加州大学旧金山分校的Lietman TM近日在PLoS Negl Trop Dis杂志上发表了一篇文章,他们通过建立模型,来确定沙眼传播过程中的核心群体。

在许多传染病中,在传播过程中核心群体起着重要的作用。如果这些人能够通过使用可靠的疫苗等被有效地防止感染,那么该疾病可能会在这个地区部分控制。目前还没有证据表明,疫苗可以对引起沙眼的衣原体眼病菌有效。然而,口服阿奇霉素进行反复治疗可能是防止个体之间传播沙眼的有效手段。

在这篇文章里,作者假设在不同的传播程度上,研究总结了几种识别沙眼的核心方法。他们从完全指定的模型中确定最小核心组,而这符合埃塞俄比亚大型试验的结果。他们还将此标准与沙眼计划中实际发现的核心组进行比较。

因此,他们认为,对于传播过程来说,有足够的群体相对容易识别,但可能会跟理论有出入。

原文出处:

Lietman, T.M., et al., Identifying a sufficient core group for trachoma transmission. PLoS Negl Trop Dis, 2018. 12(10): p. e0006478.

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    2018-11-04 xjy13
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    2018-10-29 chenshujs
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    2018-10-29 chenshujs

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