Cell Metab:新节食方法既可减肥又可延缓衰老

2015-06-24 佚名 生物谷

近日,来自美国南加州大学的研究人员在国际学术期刊cell metabolism在线发表了一项最新研究进展,他们发现周期性摄入能够模拟饥饿效应的低卡路里饮食(FMD)可能对健康大有益处。   在这项新研究中,研究人员发现周期性摄入低卡路里饮食能够减少内脏脂肪,并能够增加老年小鼠一些重要器官中始祖细胞和干细胞的数目,其中包括大脑,研究人员发现这种饮食方法能够促进神经元再生并可以提高学习和

近日,来自美国南加州大学的研究人员在国际学术期刊cell metabolism在线发表了一项最新研究进展,他们发现周期性摄入能够模拟饥饿效应的低卡路里饮食(FMD)可能对健康大有益处。

 
在这项新研究中,研究人员发现周期性摄入低卡路里饮食能够减少内脏脂肪,并能够增加老年小鼠一些重要器官中始祖细胞和干细胞的数目,其中包括大脑,研究人员发现这种饮食方法能够促进神经元再生并可以提高学习和记忆能力。
 
除小鼠之外,研究人员还利用了酵母和人群进行相关研究。小鼠的寿命相对较短,能够为低卡路里饮食对寿命的影响提供一些细节信息;酵母是一种相对简单的真核生物,但却是在细胞水平上揭示低卡路里饮食触发的生物学机制的理想模型;而利用人群进行先导性研究能够为基于小鼠和酵母进行的研究提供有力支持。
 
在该研究中,研究人员以4天为一个低卡路里饮食期限,每两个月进行一次FMD饮食,对中等年龄的小鼠进行了研究,结果表明这种饮食方法可以延长寿命,降低癌症的发生,促进免疫系统功能,降低炎症疾病发生,延缓骨矿物质密度损失并能增强老年小鼠的认知学习能力。但这种FMD饮食小组和对照饮食小组的月总卡路里摄取是相同的,这表明这种健康获益并不是靠完全控制饮食实现的。
 
而在先导性人群研究中,研究人员选取了19名参与者,给予类似的低卡路里饮食,每个月进行一次,一次持续5天,结果发现与衰老,糖尿病,心血管疾病和癌症有关的生物标记物和风险因子都出现下降,同时没有发现任何有害副作用。
 
研究人员最后指出,严格的饥饿状态对于人们来说很难保持,同时也是非常具有危险性的,而这种周期性低卡路里饮食策略能够在体内触发相同的健康效应,同时这种方法也更加容易更加安全。
 
总得来说,这项研究表明低卡路里饮食对健康有很大益处,同时还证明摄入模拟饥饿效应的低卡路里饮食对于减肥、抗衰老、抗糖尿病、抗癌都非常有好处,是一种更加简单更加安全的好方法。

原始出处:

Sebastian Brandhorst15, In Young Choi15, Min Wei et al.A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan.Cell Metabolism, June 18, 2015.DOI: http://dx.doi.org/10.1016/j.cmet.2015.05.012

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    2015-10-26 智智灵药
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encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Wed Sep 16 17:08:00 CST 2015, time=2015-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887445, encodeId=a805188e445dc, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Tue Oct 06 17:08:00 CST 2015, time=2015-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33120, encodeId=dbd6331201c, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=, createdTime=Sun Jul 19 17:08:00 CST 2015, time=2015-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=30301, encodeId=3e59303018b, content=真的嘛!!太有意思了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170803/IMG5982F7A3DBB3C1061.jpg, createdBy=0ba51605600, createdName=Jianghuiqin, createdTime=Fri Jul 03 11:14:00 CST 2015, time=2015-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1414115, encodeId=663f141411579, content=<a href='/topic/show?id=e215868e93c' target=_blank style='color:#2F92EE;'>#节食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86879, encryptionId=e215868e93c, topicName=节食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=da0d3042812, createdName=lsndxfj, createdTime=Fri Jun 26 00:08:00 CST 2015, time=2015-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=29117, encodeId=59ff2911ee7, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Thu Jun 25 22:15:00 CST 2015, time=2015-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=28893, encodeId=cc0c28893d6, content=饿着好, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Thu Jun 25 13:27:00 CST 2015, time=2015-06-25, status=1, ipAttribution=)]
    2015-09-16 一闲
  5. [GetPortalCommentsPageByObjectIdResponse(id=1932364, encodeId=b9211932364fe, content=<a href='/topic/show?id=d8de4951168' target=_blank style='color:#2F92EE;'>#延缓衰老#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49511, encryptionId=d8de4951168, topicName=延缓衰老)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7f52347, createdName=soongzhihua, createdTime=Sat Feb 20 18:08:00 CST 2016, time=2016-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1959401, encodeId=4caa195940188, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Mon Oct 26 13:08:00 CST 2015, time=2015-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1869147, encodeId=fee5186914e6e, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Apr 20 15:08:00 CST 2016, time=2016-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1895811, encodeId=a7411895811bc, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Wed Sep 16 17:08:00 CST 2015, time=2015-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887445, encodeId=a805188e445dc, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Tue Oct 06 17:08:00 CST 2015, time=2015-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33120, encodeId=dbd6331201c, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=, createdTime=Sun Jul 19 17:08:00 CST 2015, time=2015-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=30301, encodeId=3e59303018b, content=真的嘛!!太有意思了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170803/IMG5982F7A3DBB3C1061.jpg, createdBy=0ba51605600, createdName=Jianghuiqin, createdTime=Fri Jul 03 11:14:00 CST 2015, time=2015-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1414115, encodeId=663f141411579, content=<a href='/topic/show?id=e215868e93c' target=_blank style='color:#2F92EE;'>#节食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86879, encryptionId=e215868e93c, topicName=节食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=da0d3042812, createdName=lsndxfj, createdTime=Fri Jun 26 00:08:00 CST 2015, time=2015-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=29117, encodeId=59ff2911ee7, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Thu Jun 25 22:15:00 CST 2015, time=2015-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=28893, encodeId=cc0c28893d6, content=饿着好, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Thu Jun 25 13:27:00 CST 2015, time=2015-06-25, status=1, ipAttribution=)]
    2015-10-06 guojianrong
  6. [GetPortalCommentsPageByObjectIdResponse(id=1932364, encodeId=b9211932364fe, content=<a href='/topic/show?id=d8de4951168' target=_blank style='color:#2F92EE;'>#延缓衰老#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49511, encryptionId=d8de4951168, topicName=延缓衰老)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7f52347, createdName=soongzhihua, createdTime=Sat Feb 20 18:08:00 CST 2016, time=2016-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1959401, encodeId=4caa195940188, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, 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encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Wed Sep 16 17:08:00 CST 2015, time=2015-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887445, encodeId=a805188e445dc, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Tue Oct 06 17:08:00 CST 2015, time=2015-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33120, encodeId=dbd6331201c, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=, createdTime=Sun Jul 19 17:08:00 CST 2015, time=2015-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=30301, encodeId=3e59303018b, content=真的嘛!!太有意思了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170803/IMG5982F7A3DBB3C1061.jpg, createdBy=0ba51605600, createdName=Jianghuiqin, createdTime=Fri Jul 03 11:14:00 CST 2015, time=2015-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1414115, encodeId=663f141411579, content=<a href='/topic/show?id=e215868e93c' target=_blank style='color:#2F92EE;'>#节食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86879, encryptionId=e215868e93c, topicName=节食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=da0d3042812, createdName=lsndxfj, createdTime=Fri Jun 26 00:08:00 CST 2015, time=2015-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=29117, encodeId=59ff2911ee7, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Thu Jun 25 22:15:00 CST 2015, time=2015-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=28893, encodeId=cc0c28893d6, content=饿着好, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Thu Jun 25 13:27:00 CST 2015, time=2015-06-25, status=1, ipAttribution=)]
    2015-07-19 匿名用户

    长见识了

    0

  7. [GetPortalCommentsPageByObjectIdResponse(id=1932364, encodeId=b9211932364fe, content=<a href='/topic/show?id=d8de4951168' target=_blank style='color:#2F92EE;'>#延缓衰老#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=49511, encryptionId=d8de4951168, topicName=延缓衰老)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=7f52347, createdName=soongzhihua, createdTime=Sat Feb 20 18:08:00 CST 2016, time=2016-02-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1959401, encodeId=4caa195940188, content=<a href='/topic/show?id=dbe6445416' target=_blank style='color:#2F92EE;'>#CEL#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4454, encryptionId=dbe6445416, topicName=CEL)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=a12645, createdName=智智灵药, createdTime=Mon Oct 26 13:08:00 CST 2015, time=2015-10-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1869147, encodeId=fee5186914e6e, content=<a href='/topic/show?id=fd764459a8' target=_blank style='color:#2F92EE;'>#Cell#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=4459, encryptionId=fd764459a8, topicName=Cell)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=524d95, createdName=zhaozhouchifen, createdTime=Wed Apr 20 15:08:00 CST 2016, time=2016-04-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1895811, encodeId=a7411895811bc, content=<a href='/topic/show?id=4a391158248' target=_blank style='color:#2F92EE;'>#MET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11582, encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Wed Sep 16 17:08:00 CST 2015, time=2015-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887445, encodeId=a805188e445dc, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Tue Oct 06 17:08:00 CST 2015, time=2015-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33120, encodeId=dbd6331201c, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=, createdTime=Sun Jul 19 17:08:00 CST 2015, time=2015-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=30301, encodeId=3e59303018b, content=真的嘛!!太有意思了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170803/IMG5982F7A3DBB3C1061.jpg, createdBy=0ba51605600, createdName=Jianghuiqin, createdTime=Fri Jul 03 11:14:00 CST 2015, time=2015-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1414115, encodeId=663f141411579, content=<a href='/topic/show?id=e215868e93c' target=_blank style='color:#2F92EE;'>#节食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86879, encryptionId=e215868e93c, topicName=节食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=da0d3042812, createdName=lsndxfj, createdTime=Fri Jun 26 00:08:00 CST 2015, time=2015-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=29117, encodeId=59ff2911ee7, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Thu Jun 25 22:15:00 CST 2015, time=2015-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=28893, encodeId=cc0c28893d6, content=饿着好, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Thu Jun 25 13:27:00 CST 2015, time=2015-06-25, status=1, ipAttribution=)]
    2015-07-03 Jianghuiqin

    真的嘛!!太有意思了!

    0

  8. 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encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Wed Sep 16 17:08:00 CST 2015, time=2015-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887445, encodeId=a805188e445dc, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Tue Oct 06 17:08:00 CST 2015, time=2015-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33120, encodeId=dbd6331201c, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=, createdTime=Sun Jul 19 17:08:00 CST 2015, time=2015-07-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=30301, encodeId=3e59303018b, content=真的嘛!!太有意思了!, beContent=null, objectType=article, channel=null, level=null, likeNumber=93, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170803/IMG5982F7A3DBB3C1061.jpg, createdBy=0ba51605600, createdName=Jianghuiqin, createdTime=Fri Jul 03 11:14:00 CST 2015, time=2015-07-03, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1414115, encodeId=663f141411579, content=<a href='/topic/show?id=e215868e93c' target=_blank style='color:#2F92EE;'>#节食#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=27, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=86879, encryptionId=e215868e93c, topicName=节食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=da0d3042812, createdName=lsndxfj, createdTime=Fri Jun 26 00:08:00 CST 2015, time=2015-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=29117, encodeId=59ff2911ee7, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Thu Jun 25 22:15:00 CST 2015, time=2015-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=28893, encodeId=cc0c28893d6, content=饿着好, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Thu Jun 25 13:27:00 CST 2015, time=2015-06-25, status=1, ipAttribution=)]
    2015-06-26 lsndxfj
  9. 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encryptionId=4a391158248, topicName=MET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=18fc139, createdName=一闲, createdTime=Wed Sep 16 17:08:00 CST 2015, time=2015-09-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1887445, encodeId=a805188e445dc, content=<a href='/topic/show?id=d56611584ec' target=_blank style='color:#2F92EE;'>#Meta#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=11584, encryptionId=d56611584ec, topicName=Meta)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d8f4110, createdName=guojianrong, createdTime=Tue Oct 06 17:08:00 CST 2015, time=2015-10-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=33120, encodeId=dbd6331201c, content=长见识了, beContent=null, objectType=article, channel=null, level=null, likeNumber=174, replyNumber=0, topicName=null, topicId=null, topicList=[], 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encryptionId=e215868e93c, topicName=节食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=da0d3042812, createdName=lsndxfj, createdTime=Fri Jun 26 00:08:00 CST 2015, time=2015-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=29117, encodeId=59ff2911ee7, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Thu Jun 25 22:15:00 CST 2015, time=2015-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=28893, encodeId=cc0c28893d6, content=饿着好, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Thu Jun 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    2015-06-25 huaxipanxing

    看看

    0

  10. 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encryptionId=e215868e93c, topicName=节食)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=da0d3042812, createdName=lsndxfj, createdTime=Fri Jun 26 00:08:00 CST 2015, time=2015-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=29117, encodeId=59ff2911ee7, content=看看, beContent=null, objectType=article, channel=null, level=null, likeNumber=141, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ee0d1618732, createdName=huaxipanxing, createdTime=Thu Jun 25 22:15:00 CST 2015, time=2015-06-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=28893, encodeId=cc0c28893d6, content=饿着好, beContent=null, objectType=article, channel=null, level=null, likeNumber=164, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=48ce1618316, createdName=stupidox, createdTime=Thu Jun 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    2015-06-25 stupidox

    饿着好

    0

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