CHEST:健康人运动时的心输出量参考值与计算方程式

2017-01-22 MedSci MedSci原创

心输出量(Q)是评估心脏功能的关键参数,其测量对于所有心脏病的诊断、治疗和预后评估至关重要。直到最近,在峰值运动的Q测定已经可能通过侵入性方法实现,使得可以在基于小群体的研究中获得正常值。如今,峰Q可以通过惰性气体再呼吸技术(IGR)无创测量。进行研究以提供正常群体中峰Q的参考值,并获得能够从测量的峰值氧摄取(VO2)估计峰值运动Q的公式。研究者研究了500名正常受试者(年龄44.9±1.5岁,范

心输出量(Q)是评估心脏功能的关键参数,其测量对于所有心脏病的诊断、治疗和预后评估至关重要。直到最近,在峰值运动的Q测定已经可以通过侵入性方法得到,使得可以在基于小群体的研究中获得正常值。

如今,峰Q可以通过惰性气体再呼吸技术(IGR)进行无创测量。发表在CHEST杂志上的文章研究了正常群体中峰Q的参考值,并提出了从测量的峰值氧摄取(VO2)估计峰值运动Q的公式。

研究者研究了500名正常受试者(年龄44.9±1.5岁,范围18-77,260名男性,240名女性),其经过IGR峰值Q测量的最大心肺运动测试。在整体研究样本中,峰值Q为13.2±3.5L / min(男性:15.3±3.3L / min;女性:11.0±2.0L / min,p <0.001),峰值VO2为最大预测值的95±18%(男性:95±19%;女性:95±18%)。峰值VO2和峰值Q随年龄逐渐降低(分别为:R2:0.082,p <0.001和R2:0.144,p <0.001)。

在整体研究群组中,在峰值运动时测量Q的VO2衍生公式为:(4.4×峰值VO2)+4.3,男性组为:(4.3×峰值VO2)+4.5;女性组为:(4.9×峰值VO2)+ 3.6。

此项研究结论为:在健康受试者的大样本中,峰值运动时可以同时测量Q;VO2可以提供从峰值VO2值预测峰Q的方程。

原始出处:
Agostoni P, Vignati C, Gentile P, et al. Reference values for peak exercise cardiac output in healthy individuals.Chest. 2017 Jan 17. pii: S0012-3692(17)30020-X.

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    2017-07-29 Smile2680
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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Tue Jan 24 07:45:55 CST 2017, time=2017-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172223, encodeId=18091e2223e6, content=很好的学习资料收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170207/IMG589913E36908D4741.jpg, createdBy=99331680071, createdName=knowheart, createdTime=Mon Jan 23 22:13:13 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172089, encodeId=be1f1e208952, content=学习了好东西!, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Jan 23 08:40:39 CST 2017, time=2017-01-23, status=1, ipAttribution=)]
    2017-01-25 李东泽

    很好,不错,以后会多学习

    0

  5. 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  6. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Tue Jan 24 07:45:55 CST 2017, time=2017-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172223, encodeId=18091e2223e6, content=很好的学习资料收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170207/IMG589913E36908D4741.jpg, createdBy=99331680071, createdName=knowheart, createdTime=Mon Jan 23 22:13:13 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172089, encodeId=be1f1e208952, content=学习了好东西!, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Jan 23 08:40:39 CST 2017, time=2017-01-23, status=1, ipAttribution=)]
    2017-01-24 wmu姿

    以后运动更有意义了

    0

  7. 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topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Jan 23 08:40:39 CST 2017, time=2017-01-23, status=1, ipAttribution=)]
    2017-01-24 天涯183

    学习了,收益

    0

  8. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Tue Jan 24 07:45:55 CST 2017, time=2017-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172223, encodeId=18091e2223e6, content=很好的学习资料收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170207/IMG589913E36908D4741.jpg, createdBy=99331680071, createdName=knowheart, createdTime=Mon Jan 23 22:13:13 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172089, encodeId=be1f1e208952, content=学习了好东西!, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Jan 23 08:40:39 CST 2017, time=2017-01-23, status=1, ipAttribution=)]
    2017-01-24 天涯183

    学习了,收益

    0

  9. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Tue Jan 24 07:45:55 CST 2017, time=2017-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172223, encodeId=18091e2223e6, content=很好的学习资料收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170207/IMG589913E36908D4741.jpg, createdBy=99331680071, createdName=knowheart, createdTime=Mon Jan 23 22:13:13 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172089, encodeId=be1f1e208952, content=学习了好东西!, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Jan 23 08:40:39 CST 2017, time=2017-01-23, status=1, ipAttribution=)]
    2017-01-23 knowheart

    很好的学习资料收藏

    0

  10. 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attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7LIiaRZTzJ3SEfiauCzTMPW7YvPPYLNJBXG9oh6Al1icq2VQQkIHWxqXehcicTS62YKJVBhxeth3wggw/0, createdBy=7ce01621306, createdName=天涯183, createdTime=Tue Jan 24 07:45:55 CST 2017, time=2017-01-24, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172223, encodeId=18091e2223e6, content=很好的学习资料收藏, beContent=null, objectType=article, channel=null, level=null, likeNumber=81, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20170207/IMG589913E36908D4741.jpg, createdBy=99331680071, createdName=knowheart, createdTime=Mon Jan 23 22:13:13 CST 2017, time=2017-01-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=172089, encodeId=be1f1e208952, content=学习了好东西!, beContent=null, objectType=article, channel=null, level=null, likeNumber=36, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=92191944782, createdName=thlabcde, createdTime=Mon Jan 23 08:40:39 CST 2017, time=2017-01-23, status=1, ipAttribution=)]
    2017-01-23 thlabcde

    学习了好东西!

    0

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