Obstet Gynecol:母亲种族/民族差异对新生儿不良出生结局的影响不同

2017-05-31 MedSci MedSci原创

近期发表在Obstet Gynecol上的一项研究探讨了借助或不借助辅助生殖技术(ART)的单胎生产中,孕妇的种族/民族对早产儿和低出生体重儿(LBW)的影响差异。本研究是一项回顾性队列研究,使用了2000-2010年间美国马萨诸塞州、佛罗里达州居民出生证明数据和国家ART监测系统的数据。有4568822个活产婴儿被纳入研究,其中有64834名借助于ART。研究人员使用χ测试比较了跨种族/民族组产

近期发表在Obstet Gynecol上的一项研究探讨了借助或不借助辅助生殖技术(ART)的单胎生产中,孕妇的种族/民族对早产儿和低出生体重儿(LBW)的影响差异。

本研究是一项回顾性队列研究,使用了2000-2010年间美国马萨诸塞州、佛罗里达州居民出生证明数据和国家ART监测系统的数据。有4568822个活产婴儿被纳入研究,其中有64834名借助于ART。研究人员使用χ测试比较了跨种族/民族组产妇间的单胎活产新生儿的母体和ART的周期特性,并使用对数二项式模型探讨了借助了ART生产的母亲的种族/民族与低出生体重、早产之间的关系。

借助于ART的活产新生儿的比例因孕妇的种族/民族而不同(P<0.01)。其中,与非西班牙裔白人孕妇的新生儿活产率(2%)和亚洲或太平洋岛民孕妇的(1.9%)对比,非西班牙裔黑人孕妇的新生儿活产率(0.3%)和西班牙裔孕妇的(0.6%)最小。低出生体重、早产百分比在非西班牙裔黑人女性的新生儿中最高,即使不借助ART(分别是11.3%、12.4%),即使借助ART(分别为16.1%、19.1%)。调整母体因素后,单胎生产时,与非西班牙裔白人妇女的新生儿相比,低出生体重、早产儿在非西班牙裔黑人母亲中的风险较高,在不借助ART孕妇中该风险升高2.12 [ 95%置信区间(CI),2.10-2.14 ]和1.56倍(95% CI,1.54-1.57),在借助ART的孕妇中该风险升高1.87倍(95% CI,1.57-2.23)和1.56倍(95% CI,1.34-1.83)。无论是否借助ART,与非西班牙裔白人女性相比,低出生体重的调整后风险在西班牙裔(调整后的相对危险[RR],1.26;95% CI,1.09-1.47;同时,调整RR,1.15;95% CI,1.13-1.16)和亚洲或太平洋岛民(RR,1.39;95% CI,1.16-1.65;同时,调整RR,1.55;95% CI,1.52-1.58)中依然显著较高。

研究表明,是否借助ART,孕产妇的种族/民族差异造成的不良围产期结果也不同。

原始出处:

Crawford S1, Joshi N, et al.Maternal Racial and Ethnic Disparities in Neonatal Birth Outcomes With and Without Assisted Reproduction.Obstet Gynecol. 2017 Jun;129(6):1022-1030. doi: 10.1097/AOG.0000000000002031.

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    2017-07-05 yhy100200
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  4. [GetPortalCommentsPageByObjectIdResponse(id=1981387, encodeId=2cdd198138e2f, content=<a href='/topic/show?id=9e3331440a2' target=_blank style='color:#2F92EE;'>#出生结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31440, encryptionId=9e3331440a2, topicName=出生结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Wed Nov 01 08:43:00 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011306, encodeId=79b62011306d1, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Wed Jul 05 03:43:00 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2043969, encodeId=120e2043969e4, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Mon Nov 20 04:43:00 CST 2017, time=2017-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=205503, encodeId=2ecd205503e5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Fri Jun 02 07:55:42 CST 2017, time=2017-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=205094, encodeId=241120509459, content=母亲种族/民族差异对新生儿不良出生结局的影响不同, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Thu Jun 01 06:50:57 CST 2017, time=2017-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=205090, encodeId=009e20509087, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Thu Jun 01 06:43:05 CST 2017, time=2017-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=204966, encodeId=006a20496612, content=谢谢分享。 , beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed May 31 23:14:40 CST 2017, time=2017-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=204957, encodeId=6b9520495e88, content=研究表明,是否借助ART,孕产妇的种族/民族差异造成的不良围产期结果也不同。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Wed May 31 22:56:06 CST 2017, time=2017-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=204943, encodeId=0b56204943dd, content=恩,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuBA90ng5ibXMmibn1feGOQ2cjw0S48DKsF0icicFlmRxwHibIic2TNGd22vVqkKRMj2cRSWbpqZAPBPgdt/0, createdBy=81031668757, createdName=林3301, createdTime=Wed May 31 22:35:24 CST 2017, time=2017-05-31, status=1, ipAttribution=)]
    2017-06-02 lou.minghong

    学习

    0

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    2017-06-01 ann y

    母亲种族/民族差异对新生儿不良出生结局的影响不同

    0

  6. [GetPortalCommentsPageByObjectIdResponse(id=1981387, encodeId=2cdd198138e2f, content=<a href='/topic/show?id=9e3331440a2' target=_blank style='color:#2F92EE;'>#出生结局#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=31440, encryptionId=9e3331440a2, topicName=出生结局)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=c48a270, createdName=Smile2680, createdTime=Wed Nov 01 08:43:00 CST 2017, time=2017-11-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2011306, encodeId=79b62011306d1, content=<a href='/topic/show?id=840d1e300e5' target=_blank style='color:#2F92EE;'>#TET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=38, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17300, encryptionId=840d1e300e5, topicName=TET)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=cc52251, createdName=yhy100200, createdTime=Wed Jul 05 03:43:00 CST 2017, time=2017-07-05, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2043969, encodeId=120e2043969e4, content=<a href='/topic/show?id=8513126129d' target=_blank style='color:#2F92EE;'>#NEC#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=24, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12612, encryptionId=8513126129d, topicName=NEC)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=4dfa37, createdName=智者为医08, createdTime=Mon Nov 20 04:43:00 CST 2017, time=2017-11-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=205503, encodeId=2ecd205503e5, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=68, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib2JlGvwpAibiaovVhfA9DbO7X7JLGGjM4Cic6oMgxLdnuS9piaP9cnG2OwIbkzHvX0qzS1boibyYNqR5vHZu7HQs5EIB/0, createdBy=298d1398341, createdName=lou.minghong, createdTime=Fri Jun 02 07:55:42 CST 2017, time=2017-06-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=205094, encodeId=241120509459, content=母亲种族/民族差异对新生儿不良出生结局的影响不同, beContent=null, objectType=article, channel=null, level=null, likeNumber=0, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mStl88fu4NfNLvzZhgPxRrYOibkVibW9vAkCfb2F55aHjqMoqUVaF9fuXIMCxexawSOsicpbF7Ria7o54zPK65PodlkwhPrNhLhS/0, createdBy=12f71314239, createdName=ann y, createdTime=Thu Jun 01 06:50:57 CST 2017, time=2017-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=205090, encodeId=009e20509087, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Thu Jun 01 06:43:05 CST 2017, time=2017-06-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=204966, encodeId=006a20496612, content=谢谢分享。 , beContent=null, objectType=article, channel=null, level=null, likeNumber=61, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzfPkmqRTH5rHib5mcib8Wb3QdXjhfOK1UubQL2lictjJFdFJ6Lc3cnnCOSWqxXZ4Kk6y5GdzDoy764R/0, createdBy=156e1644785, createdName=doctorJiangchao, createdTime=Wed May 31 23:14:40 CST 2017, time=2017-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=204957, encodeId=6b9520495e88, content=研究表明,是否借助ART,孕产妇的种族/民族差异造成的不良围产期结果也不同。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7cJ6ejWUr2nIia8qOvAKNdLHr32Df6G8iaoaOx6pHaoiacwp26DaslxZHCGbibZhhCGven4rvmWP60GahtzgFjgCjR/0, createdBy=6b111703011, createdName=有备才能无患, createdTime=Wed May 31 22:56:06 CST 2017, time=2017-05-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=204943, encodeId=0b56204943dd, content=恩,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=26, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuBA90ng5ibXMmibn1feGOQ2cjw0S48DKsF0icicFlmRxwHibIic2TNGd22vVqkKRMj2cRSWbpqZAPBPgdt/0, createdBy=81031668757, createdName=林3301, createdTime=Wed May 31 22:35:24 CST 2017, time=2017-05-31, status=1, ipAttribution=)]
    2017-06-01 飛歌

    学习了很有用

    0

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    2017-05-31 doctorJiangchao

    谢谢分享。

    0

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    2017-05-31 有备才能无患

    研究表明,是否借助ART,孕产妇的种族/民族差异造成的不良围产期结果也不同。

    0

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    2017-05-31 林3301

    恩,学习了

    0

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