OCC 2014:HTN-3是肾神经消融术的终结者么?

2014-06-05 小田 整理 医学论坛网

在东方心脏病学会议(OCC2014)31日下午的难治性高血压专场上,上海交通大学医学院附属第九人民医院许建忠教授做了“Symplicity HTN-3是肾神经消融术的终结者么?”的报告。 他回顾了近期的HTN-3研究,并对去神交感神经(RDN)治疗难治性高血压进行了总结和评论。他认为,HTN-3研究不能否定肾交感神经过度激活在高血压中作用的理论基础,更不能否定RDN降压治疗的实践结果;目前基

在东方心脏病学会议(OCC2014)31日下午的难治性高血压专场上,上海交通大学医学院附属第九人民医院许建忠教授做了“Symplicity HTN-3是肾神经消融术的终结者么?”的报告。


他回顾了近期的HTN-3研究,并对去神交感神经(RDN)治疗难治性高血压进行了总结和评论。他认为,HTN-3研究不能否定肾交感神经过度激活在高血压中作用的理论基础,更不能否定RDN降压治疗的实践结果;目前基础研究仍是RDN的重点。

他还表示,HTN-3研究的失败从某种意义上来说只是证明了单电极消融导管应用的失败,对其他类型的导管(如螺旋型的、超声和冷冻球囊等)并不适用,我们有理由相信,不同的器械和操作方式,其结果应该也不一样。RDN术并不是那么容易操作,可能需要建立资质认证。而且手术缺乏明确的生物学终点是亟需解决的问题。他还认为,RDN可能只在部分而非全部患者中有效,其应用或许应限于肾脏交感神经过度激活是难治性高血压主要病因的患者。另外,许教授指出,不同种族的RDN效果可能不一样,中国需要有自己的数据。

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    2015-02-04 雕雕
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    2014-06-07 zhaojie88
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