Stroke：老年人心率与亚临床脑血管病有关！

2017-12-29 xing.T MedSci原创

在一个以老年人为主的队列中，研究结果表明夜间心率升高与WMHV相关，提示心率在亚临床脑血管病中发挥着独立的作用。

虽然心率增加是心血管事件和死亡率的预测因素，但它与亚临床脑血管病的可能联系在老年人中很普遍，这种关系尚未被评估。近日，卒中领域权威杂志Stroke上发表了一篇研究文章，该研究旨在探讨无卒中史的老年人群白天、夜间、24小时心率以及心率变异性与亚临床脑血管病之间的关系。

研究对象包括680名窦性心律的参与者（平均年龄73±7岁；42%为男性），这些参与者接受了24h动态血压和心率监测、二维超声心动图、脑磁共振成像检查，作为CABL（心脏异常和脑病变）研究的一部分。亚临床脑血管病被定义为无症状性脑梗死和白质高信号体积（WMHV）。研究人员分析了心率指标与无症状脑梗死和WMHV对数上四分位数（logWMHV4）之间的关系。

研究人员发现93名（13.7%）参与者存在无症状性脑梗塞；平均WMHV对数为-0.92±0.93（中位数为-1.05；最小为-5.88；最大为1.74）。多因素分析显示，只有夜间心率（调整后的比值比为1.29每10次/分；95%可信区间为1.03-1.61；P=0.026）与WMHV对数显著相关，且独立于传统的心血管危险因素，动态收缩压以及超声心动图参数。白天心率和心率变异性与WMHV对数之间没有观察到类似的联系。所有心率指标与无症状脑梗塞之间无显著关联。

在一个以老年人为主的队列中，研究结果表明夜间心率升高与WMHV相关，提示心率在亚临床脑血管病中发挥着独立的作用。

原始出处：

Koki Nakanishi, et al. Association Between Heart Rate and Subclinical Cerebrovascular Disease in the Elderly.Stroke. 2017. https://doi.org/10.1161/STROKEAHA.117.019355

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2018-06-07 Luyuxie_17

#血管病#

27 0
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2018-01-09 大爰

学习了谢谢分享!!

76 0
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2018-01-02 大爰

学习了谢谢分享!!

71 0
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2018-01-02 jyzxjiangqin

老年人心率与亚临床脑血管病.

67 0
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2017-12-31 123158062

好

69 0
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2017-12-31 123158062

很好

77 0
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2017-12-31 123158062

学习了

24 0
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2017-12-30 半夏微凉

学习了.谢谢分享

23 0
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2017-12-29 神功盖世

学习

21 0
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2017-12-29 天涯183

非常好的文章.学习了

28 0