Eye (Lond):Vogt-Koyanagi-Harada病患者不同部位之间光感受器恢复的差异!

2017-12-06 cuiguizhong MedSci原创

上海复旦大学上海医学院眼科和耳鼻喉科医院眼科的Zhou M近日在Eye (Lond)发表了他们的一项工作,探讨了Vogt-Koyanagi-Harada(VKH)疾病治疗后光感受器的恢复情况。

上海复旦大学上海医学院眼科和耳鼻喉科医院眼科的Zhou M近日在Eye (Lond)发表了他们的一项工作,探讨了Vogt-Koyanagi-Harada(VKH)疾病治疗后光感受器的恢复情况。

他们进行了回顾性研究。总共招募了28例VKH患者,共56例眼睛。在治疗后12个月,记录临床和光学相干断层扫描(OCT)的结果。OCT上的光感受器恢复程度定义为:模式F组为中心凹视网膜光感受器首先恢复;模式E组为外部光感受器首先恢复; S组为中心凹和视网膜外的光感受器同时恢复。

结果他们发现,患者眼底不同部位的光感受器恢复情况不同。 F组56眼中,10只眼的椭圆形区(EZ)得到恢复,17只眼的交错区(IZ)得到恢复。在大多数眼睛中(其中EZ 有46例眼,IZ有 26例眼),这些结构的恢复类型是S型。仅在10只眼中,IZ的恢复是E型。通过比较治疗后12个月的解剖和视力结果发现,不同的恢复模式与患者的不同的恢复治疗方式有关。与对照组相比,F组患者延迟治疗,EZ或IZ恢复延迟,12个月时预后较差,而E组患者治疗和恢复最为迅速,且更为有利。

因此,他们认为,在延迟治疗的VKH患者中,中央凹感光器的恢复速度比其他区域的感光器更快。

原文出处


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likeNumber=56, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cdnapi.center.medsci.cn/medsci/head/2017/04/21/72142930668371951a41ef4ea4b233e6.jpg, createdBy=dcbc1715228, createdName=刘煜, createdTime=Thu Dec 07 06:00:15 CST 2017, time=2017-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=267407, encodeId=a81226e407ad, content=非常好.谢谢分享, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/10/21/9461f3b3c9f14e1d844256cdd08f2cf3.jpg, createdBy=a30f1426910, createdName=swfzhanggui, createdTime=Thu Dec 07 05:32:48 CST 2017, time=2017-12-07, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=267405, encodeId=c5a426e40545, content=好好好好好好好好, beContent=null, objectType=article, channel=null, level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Dec 07 05:32:07 CST 2017, time=2017-12-07, status=1, ipAttribution=)]
    2017-12-08 般若傻瓜
  5. 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level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Dec 07 05:32:07 CST 2017, time=2017-12-07, status=1, ipAttribution=)]
    2017-12-08 txqjm

    谢谢了.学习

    0

  6. 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level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Dec 07 05:32:07 CST 2017, time=2017-12-07, status=1, ipAttribution=)]
    2017-12-07 榄枷檬

    谢谢分享

    0

  7. 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level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Dec 07 05:32:07 CST 2017, time=2017-12-07, status=1, ipAttribution=)]
    2017-12-07 榄枷檬

    学习学习

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1633430, encodeId=403c1633430ba, content=<a href='/topic/show?id=377824e1c0' target=_blank style='color:#2F92EE;'>#ANA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2471, encryptionId=377824e1c0, topicName=ANA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=434d22047430, createdName=AspirantSuo, createdTime=Tue Oct 23 01:27:00 CST 2018, time=2018-10-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=2029837, encodeId=4acc202983ebb, content=<a href='/topic/show?id=fedde18245' target=_blank style='color:#2F92EE;'>#eye#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=7182, encryptionId=fedde18245, topicName=eye)], attachment=null, authenticateStatus=null, 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level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Dec 07 05:32:07 CST 2017, time=2017-12-07, status=1, ipAttribution=)]
    2017-12-07 刘煜

    阅读.谢谢分享

    0

  9. 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level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Dec 07 05:32:07 CST 2017, time=2017-12-07, status=1, ipAttribution=)]
    2017-12-07 swfzhanggui

    非常好.谢谢分享

    0

  10. 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level=null, likeNumber=16, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/08/29/bbc5cc0eed9b8d17623d2fd49dbdf19a.jpg, createdBy=79522135794, createdName=yjs木玉, createdTime=Thu Dec 07 05:32:07 CST 2017, time=2017-12-07, status=1, ipAttribution=)]
    2017-12-07 yjs木玉

    好好好好好好好好

    0