JAHA:难治性高血压能明显增加T2DM患者肾脏疾病发生的风险

2017-09-23 MedSci MedSci原创

难治性高血压(aTRH)在2型糖尿病(T2DM)患者中较为常见,并且会影响患者预后。目前,aTRH和推荐的血压长期管理对肾脏结局的影响尚未阐明。近日,在国际心血管权威杂志JAHA上发表了一篇旨在评估aTRH和血压对2型糖尿病患者预后影响的临床研究。本研究纳入了29923名T2DM和高血压患者,所有患者的基础肾小球滤过率是正常的,并对其进行4年的随访和评估。分析结果显示,有17%的患者在随访开始即伴

难治性高血压(aTRH)在2型糖尿病(T2DM)患者中较为常见,并且会影响患者预后。目前,aTRH和推荐的血压长期管理对肾脏结局的影响尚未阐明。近日,在国际心血管权威杂志JAHA上发表了一篇旨在评估aTRH和血压对2型糖尿病患者预后影响的临床研究。

本研究纳入了29923名T2DM和高血压患者,所有患者的基础肾小球滤过率是正常的,并对其进行4年的随访和评估。分析结果显示,有17%的患者在随访开始即伴有难治性高血压,随着4年时间的随访,有19%的患者出现低肾小球滤过率,12%的患者的肾小球滤过率减少≥30%。与没有难治性高血压的患者相比,伴有aTRH的患者的肾脏疾病发生风险明显更高(p<0.001)。此外,在没有难治性高血压的患者中,血压的控制管理与肾脏疾病的发生风险不呈相关性,但在伴有aTRH患者中,血压的控制管理与肾脏疾病的发生风险呈明显相关(p=0.036)。

研究结果表明,难治性高血压可明显增加2型糖尿病患者的肾脏疾病发生风险,并且血压的控制管理较难改变这种风险。

原始出处:

Francesca V et al.Resistant Hypertension, Time‐Updated Blood Pressure Values and Renal Outcome in Type 2 Diabetes Mellitus.JAHA.2017 Sep.

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    2017-09-27 虈亣靌

    谢谢分享.学习了

    0

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    2017-09-25 zhaohui6731
  4. [GetPortalCommentsPageByObjectIdResponse(id=1717737, encodeId=cd031e177372c, content=<a href='/topic/show?id=f6b01e050d5' target=_blank style='color:#2F92EE;'>#T2DM患者#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=23, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=17050, encryptionId=f6b01e050d5, topicName=T2DM患者)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b70c32458048, createdName=stfoxst, createdTime=Sun Dec 31 16:41:00 CST 2017, time=2017-12-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=248249, encodeId=223f248249a8, content=谢谢分享.学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=54, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zMoyicyo6ia9f4IuLQAwZoxD6Hx4ibd5CMcOCYhStY6oDibbKK6O2X8iaicldO5ib8j1iapOIobIKCGiczU2A/0, createdBy=56251941490, createdName=虈亣靌, createdTime=Wed Sep 27 18:36:37 CST 2017, time=2017-09-27, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1267551, encodeId=3980126e551e7, content=<a href='/topic/show?id=922f21183d' target=_blank style='color:#2F92EE;'>#AHA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=2118, encryptionId=922f21183d, topicName=AHA)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=bf3d82, createdName=zhaohui6731, createdTime=Mon Sep 25 03:41:00 CST 2017, time=2017-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1528389, encodeId=ba8c1528389c6, content=<a href='/topic/show?id=74b798601a1' target=_blank style='color:#2F92EE;'>#难治性#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=30, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=98601, encryptionId=74b798601a1, topicName=难治性)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=a1ef11916292, createdName=freve, createdTime=Mon Sep 25 03:41:00 CST 2017, time=2017-09-25, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=246990, encodeId=df46246990e4, content=饮食习惯有关, beContent=null, objectType=article, channel=null, level=null, likeNumber=59, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/05/25/aee510ed68ce4736e9fe4ec7d03c01b1.jpg, createdBy=ce892064652, createdName=楠博One, createdTime=Sat Sep 23 14:47:30 CST 2017, time=2017-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=246962, encodeId=56af24696209, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=51, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/23/7e052413cca748d8a3ad7be705b0b6f4.jpg, createdBy=4d292156689, createdName=笑香儿, createdTime=Sat Sep 23 13:34:52 CST 2017, time=2017-09-23, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=246961, encodeId=4d4124696160, content=好, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2017/09/23/7e052413cca748d8a3ad7be705b0b6f4.jpg, createdBy=4d292156689, createdName=笑香儿, createdTime=Sat Sep 23 13:33:28 CST 2017, time=2017-09-23, status=1, ipAttribution=)]
    2017-09-25 freve
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    2017-09-23 楠博One

    饮食习惯有关

    0

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    2017-09-23 笑香儿

    0

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    2017-09-23 笑香儿

    0

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