Methods Mol Biol:小鼠视网膜疾病模型中的视网膜眼底成像技术

2018-10-29 MedSci MedSci原创

德国明斯特大学医学院眼科的Alex AF等人近日在Methods Mol Biol杂志上发表了一篇文章,作者系统的讨论了视网膜眼底成像技术在实验动物中的应用。

德国明斯特大学医学院眼科的Alex AF等人近日在Methods Mol Biol杂志上发表了一篇文章,作者系统的讨论了视网膜眼底成像技术在实验动物中的应用。

小鼠体内视网膜眼底成像技术的发展开辟了一个新的研究领域,而这不仅是在眼科研究方面。这种技术可以在不需要牺牲小鼠的情况下,纵向监测病理状态(例如新血管形成或变性)的血管和细胞动态变化,可以在同一个动物中实现更长时间的观察研究。

在实验小鼠模型中使用高分辨率扫描共聚焦激光检眼镜,可以提供大范围体内成像模式的数据。最近开发的光学相干断层扫描血管造影术甚至可以实现非侵入性体内血流分析研究。

原文出处:

Alex, A.F., et al., Retinal Fundus Imaging in Mouse Models of Retinal Diseases. Methods Mol Biol, 2019. 1834: p. 253-283.

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  5. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=350921, encodeId=22b83509212f, content=学习了很有用, beContent=null, objectType=article, channel=null, level=null, likeNumber=70, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/oLAjfB7s1ib3IzoRn621JdKCFUI4XvNELcibocrAVU6aUzEVDSaf3rYH08PUYUiagGqxAEhj8g9WqqNvD1CupIpCrmnR2OrqHZh/0, createdBy=7f181365728, createdName=飛歌, createdTime=Tue Oct 30 07:18:59 CST 2018, time=2018-10-30, status=1, ipAttribution=)]
    2019-02-26 一闲
  6. 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  7. 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    2018-10-31 zutt
  9. 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    2018-10-30 飛歌

    学习了很有用

    0

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