Diabetologia:宗耕研究组揭示麸质摄入量与2型糖尿病风险之间的关系

2018-08-14 佚名 中国科学院上海营养与健康研究院

近日,中国科学院上海生命科学研究院宗耕课题组揭示麸质摄入与长期2型糖尿病风险之间的关系,发现麸质摄入与2型糖尿病风险呈负相关。

近日,中国科学院上海生命科学研究院宗耕课题组揭示麸质摄入与长期2型糖尿病风险之间的关系,发现麸质摄入与2型糖尿病风险呈负相关。

麸质是小麦、大麦和黑麦胚乳中的主要贮藏蛋白。中国人日常饮食中,所吃的“面筋”就是面粉经过反复水洗后剩余的麸质。在全世界范围内,有少量人(约1%)对麸质过敏,导致自身免疫反应并引起乳糜泻。在过去的几年中,“无麸质饮食”在许多国家越来越受欢迎。大众普遍认为摄入无麸质饮食有益于健康,特别是对控制体重有好处。但是这种观点缺乏关于麸质摄入对人群健康影响的证据。一些小型干预研究报道,高剂量的麸质摄入(60-100g/day)对健康个体和血脂异常人群无明显副作用,而每天摄入60-80g麸质可降低血脂、血压,减少氧化应激。为了研究麸质摄入对健康的潜在影响,本研究检验了人群中典型麸质摄入量(2-12g/day)与2型糖尿病之间的关系。

通过分析三次大规模的前瞻性队列研究[The Nurses’Health Study(NHS)、NHS II、Health Professionals Follow-Up Study(HPFS)]中利用膳食调查问卷获得的随访数据,该研究发现在20-28年的随访中,调查人群(共计199794个男性和女性)的麸质摄入相对稳定,并与碳水化合物的摄入密切相关。麸质摄入最高五分位的人比最低五分位的人患2型糖尿病的风险低13%。以往在同一人群中的研究也发现,麸质摄入量与冠心病发病风险无显著关系(the British Medical Journal,2016)。

该研究是第一个研究麸质摄入与长期2型糖尿病风险之间关系的前瞻性队列研究。研究表明,对于没有麸质没有过敏反应的人群而言,刻意回避日常膳食中的麸质对预防2型糖尿病没有明显的好处,反而会导致谷物纤维和其他有益于健康的营养物质摄入降低。

相关研究成果以Gluten intake and risk of type 2 diabetes in three large prospective cohort studies of US men and women为题,发表在《糖尿病学》(Diabetologia)上。



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    2019-03-10 lmm397
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    2018-08-15 183****7028

    学习

    0

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    2018-08-15 太阳系小猪

    还有这样神奇的研究,学习了

    0

  8. [GetPortalCommentsPageByObjectIdResponse(id=1760775, encodeId=df3d1e6077521, content=<a href='/topic/show?id=9bea33520d' target=_blank style='color:#2F92EE;'>#BET#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=3352, encryptionId=9bea33520d, topicName=BET)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=9a1a37427546, createdName=ms5439512287675881, createdTime=Wed Jun 26 13:30:00 CST 2019, time=2019-06-26, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1956300, encodeId=3abe195630020, content=<a href='/topic/show?id=a74d1109c8' target=_blank style='color:#2F92EE;'>#2型糖尿病风险#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=34, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=1109, encryptionId=a74d1109c8, topicName=2型糖尿病风险)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdqq.qlogo.cn/qqapp/101296147/4E6244DB7C1860858424437821E08291/100, createdBy=a6a52500039, createdName=ms3994565386320060, createdTime=Thu Jan 31 21:30:00 CST 2019, time=2019-01-31, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1860635, encodeId=1fe51860635bd, content=<a href='/topic/show?id=830b5693631' target=_blank style='color:#2F92EE;'>#摄入量#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=48, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=56936, encryptionId=830b5693631, topicName=摄入量)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=f90281, createdName=lmm397, createdTime=Sun Mar 10 16:30:00 CST 2019, time=2019-03-10, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1638723, encodeId=ff461638e236b, content=<a href='/topic/show?id=afda591646' target=_blank style='color:#2F92EE;'>#DIA#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=39, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=5916, encryptionId=afda591646, topicName=DIA)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=987022654425, createdName=ms9608593228839890, createdTime=Fri Apr 19 19:30:00 CST 2019, time=2019-04-19, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1556662, encodeId=5f82155666270, content=<a href='/topic/show?id=0ba710300941' target=_blank style='color:#2F92EE;'>#麸质#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=103009, encryptionId=0ba710300941, topicName=麸质)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=b6da14820260, createdName=nian.wang1987, createdTime=Thu Aug 16 13:30:00 CST 2018, time=2018-08-16, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338712, encodeId=db10338e12c0, content=学习, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/vi_32/iaAVWEsIJUkA1ITy3uL0lhHUhyaJibWgFtH4KbJuaLbY2WUK33jgCFyoZ8Eqx7eE7hCuZhytc1C5GRrfjVXN8lYg/0, createdBy=fcb82149579, createdName=183****7028, createdTime=Wed Aug 15 08:37:27 CST 2018, time=2018-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338667, encodeId=d53433866e96, content=还有这样神奇的研究,学习了, beContent=null, objectType=article, channel=null, level=null, likeNumber=65, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=d7e71713450, createdName=太阳系小猪, createdTime=Wed Aug 15 07:02:25 CST 2018, time=2018-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1041781, encodeId=57bf1041e81ce, content=谢谢MedSci提供最新的资讯, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=f0620, createdName=misszhang, createdTime=Wed Aug 15 01:30:00 CST 2018, time=2018-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=338630, encodeId=7f0f33863015, content=了解一下谢谢, beContent=null, objectType=article, channel=null, level=null, likeNumber=53, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTLbTp9nZtjwVrSZNxAXbAicnKQWnic2eBdJUQYhxO36XdkstSicr7FVF8p5ReH4omtmsbnLdvZLiaJJ1A/132, createdBy=8bff2327056, createdName=kafei, createdTime=Wed Aug 15 00:09:56 CST 2018, time=2018-08-15, status=1, ipAttribution=)]
    2018-08-15 misszhang

    谢谢MedSci提供最新的资讯

    0

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    2018-08-15 kafei

    了解一下谢谢

    0

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