Advan Mater Inter:研究称能杀死细菌的石墨烯薄片可以防止植入物感染

2018-04-17 佚名 cnBeta

据外媒 New Atlas 报道,无论何时将医用植入物引入人体,其表面都可能会被细菌寄生。在某些情况下,这种感染需要移除植入物。然而,最近一项研究发现,在植入物外加上石墨烯薄片涂层可以帮助防止这种情况发生。

据外媒 New Atlas 报道,无论何时将医用植入物引入人体,其表面都可能会被细菌寄生。在某些情况下,这种感染需要移除植入物。然而,最近一项研究发现,在植入物外加上石墨烯薄片涂层可以帮助防止这种情况发生。

瑞典查尔姆斯理工大学的科学家利用被称为等离子体增强化学气相沉积的技术,在水平基底上沉积了微观垂直突出的材料薄片 - 这意味着薄片基本上变成了微小的尖状物。在实验室测试中,任何与这些石墨烯尖状物接触的细菌被它们分开并被杀死。这确实包括所谓的“良好”细菌,尽管在体内这可能无关紧要,因为在植入物表面上杀死的良好细菌数量不足以破坏患者微生物群落的整体平衡。

同样重要的是,细菌不会对石墨烯产生抗性,加上尖状物不会伤害人体细胞,因为单个细胞比单个细菌大得多 - 直径为 25 微米。作为一个附加的好处,石墨烯的结构应该有助于骨结合,这是身体的相邻骨结构生长以附着到植入物上的过程。

研究人员现在计划用石墨烯薄片涂覆实际植入物,并在动物模型中进行测试。

“石墨烯具有很高的医疗应用潜力,”查尔姆斯理工大学的的副教授 Jie Sun 表示。“但是在我们宣称它完全安全之前需要进行更多的研究。另外我们知道石墨烯不容易降解。”

关于这项研究的论文最近发表在《Advanced Materials Interfaces》杂志上。

原始出处:

Santosh Pandit  Zhejian Cao  Venkata R. S. S.et al. Vertically Aligned Graphene Coating is Bactericidal and Prevents the Formation of Bacterial Biofilms. Advanced Materials Interfaces, 2018.

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