J Natl Cancer Inst:含糖饮料摄入过多可增加胆囊癌的发生风险

2016-07-09 MedSci MedSci原创

研究已经表明摄入含糖饮料可升高血糖浓度,且与体重增加和2型糖尿病的发生密切相关,而这些都与胆道癌(BTC)的发生相关。本研究假设含糖饮料的消费量与BTC的发生风险成正相关。研究共70832名瑞典成人(55.9%为男性,年龄45-83年),均未患有癌症和糖尿病,基线时期完成了食物频率调查问卷。通过瑞典癌症登记册确定BTC病例。使用Cox比例风险回归模型来分析数据。在平均13.4年的随访期间,共有12

研究已经表明摄入含糖饮料可升高血糖浓度,且与体重增加和2型糖尿病的发生密切相关,而这些都与胆道癌(BTC)的发生相关。本研究假设含糖饮料的消费量与BTC的发生风险成正相关。

研究共70832名瑞典成人(55.9%为男性,年龄45-83年),均未患有癌症和糖尿病,基线时期完成了食物频率调查问卷。通过瑞典癌症登记册确定BTC病例。使用Cox比例风险回归模型来分析数据。

在平均13.4年的随访期间,共有127名患者发生肝外BTC(包括71名胆囊癌)和21名患者发生肝内BTC。校正其他危险因素后发现摄入含糖饮料水平最高的参与者其肝外BTC和胆囊癌的发生风险明显升高。与不摄入含糖饮料的参与者相比,每天摄入两种(200 毫升/每种)及以上含糖饮料的参与者的多变量风险比分别为1.79(肝外BTC,95% CI = 1.02-3.13)和2.24(胆囊癌,95% CI = 1.02-4.89)。肝内BTC的风险比为1.69(95% CI = 0.41-7.03)。

总而言之,该研究结果支持摄入高水平的加糖饮料可能会增加BTC的风险,尤其是胆囊癌。

原始出处:

Susanna C. Larsson, Edward L. Giovannucci, Alicja Wolk. Sweetened Beverage Consumption and Risk of Biliary Tract and Gallbladder Cancer in a Prospective Study. J Natl Cancer Inst. 2016;doi;10.1093/jnci/djw125.


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    2016-11-13 drj2003
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    2016-08-23 liye789132251
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    2016-11-01 qidongfanjian
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    2016-08-05 Mr.Li先生

    糖类摄入过多也不好

    0

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    2016-08-05 Mr.Li先生

    糖类摄入过多也不好啊

    0

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    2016-08-05 Mr.Li先生

    还是少摄入

    0

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    2016-07-16 oo902

    糖类的作用

    0

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