住院老年T2DM:综合控制血糖可防治微血管病变

2012-06-29 立影摘编 医学论坛网

  近日,卫生部北京医院内分泌科、山东大学齐鲁医院的周雁、郭立新、于冬妮等人发表论文,旨在探讨老年2型糖尿病患者微血管病变的构成比及相关因素。研究指出,对于老年2型糖尿病患者,DN、DR、DPN均与糖尿病病程和HbA1c有关,控制血糖对防治微血管病变意义重大,综合控制血糖、血压、血脂、尿酸可以更好的防治糖尿病微血管并发症。该论文发表于2012年第10期《中国老年学杂志》上。   研究人员用回顾性

  近日,卫生部北京医院内分泌科、山东大学齐鲁医院的周雁、郭立新、于冬妮等人发表论文,旨在探讨老年2型糖尿病患者微血管病变的构成比及相关因素。研究指出,对于老年2型糖尿病患者,DN、DR、DPN均与糖尿病病程和HbA1c有关,控制血糖对防治微血管病变意义重大,综合控制血糖、血压、血脂、尿酸可以更好的防治糖尿病微血管并发症。该论文发表于2012年第10期《中国老年学杂志》上。

  研究人员用回顾性分析的方法研究2003年~2010年于卫生部北京医院住院治疗的年龄≥60岁的2型糖尿病患者876例,分为糖尿病肾病(DN)组和非糖尿病肾病(非DN)组,糖尿病视网膜病变(DR)组和非糖尿病视网膜病变(非DR)组,糖尿病周围神经病变(DPN)组和非糖尿病周围神经病变(非DPN)组,计算DN、DR、DPN构成比,比较患者的临床特点,并探寻老年2型糖尿病患者DR、DN、DPN的相关因素。

  结果DN构成比为34.5%,DR构成比为42.4%,DPN构成比为82.3%。DN与非DN两组间体质量指数(BMI)、糖尿病病程、高血压病程、收缩压(SBP)、舒张压(DBP)、空腹血糖(FBS)、糖化血红蛋白(HbA1c)、空腹胰岛素(Fins)、高密度脂蛋白胆固醇(HDL)、甘油三酯(TG)、尿酸(UA)均有显著性差异;DR与非DR两组间仅糖尿病病程、SBP、空腹C肽(FCP)有显著性差异;DPN与非DPN两组间年龄、糖尿病病程、HbA1c、TC、LDL有显著性差异。Logistic回归结果显示,DN与SBP、HbA1c、FBS、HDL、UA、糖尿病病程有关;DR与SBP、HbA1c、糖尿病病程有关;DPN与HbA1c、LDL、糖尿病病程、年龄有关。

     

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    2012-07-01 mgqwxj
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