BMC Oral Health:别害怕!可以收集唾液来进行牙周筛查了

2016-07-10 MedSci MedSci原创

牙周筛查在牙周病的预防中起着很重要的作用,可促进口腔健康相关生活质量的改善。世界卫生组织的社区牙周指数应该由受过良好训练的牙医进行评估。然而,社区牙周指数是一种有创的技术,而且如果用于牙周筛查则会增加评估的成本。为了克服这些问题,我们开发了唾液测试来进行牙周筛查。本研究旨在评估该方法在测定唾液中的血红蛋白和乳酸脱氢酶水平的灵敏度和特异性。纳入标准为20岁以上的成年人,至少有20个牙齿。最后纳入38

牙周筛查在牙周病的预防中起着很重要的作用,可促进口腔健康相关生活质量的改善。世界卫生组织的社区牙周指数应该由受过良好训练的牙医进行评估。然而,社区牙周指数是一种有创的技术,而且如果用于牙周筛查则会增加评估的成本。为了克服这些问题,我们开发了唾液测试来进行牙周筛查。本研究旨在评估该方法在测定唾液中的血红蛋白和乳酸脱氢酶水平的灵敏度和特异性。

纳入标准为20岁以上的成年人,至少有20个牙齿。最后纳入38名男性和54名女性,平均年龄为50.03岁。由牙医进行口腔检查,记录余留的牙齿的数量,有无牙结石的存在,探针出血指数进而牙周袋深度。该研究中,根据美国牙周病学会与美国疾病控制和预防中心的标准定义牙周炎。为了检查唾液中的血红蛋白和乳酸脱氢酶的水平,要求参与者咀嚼5分钟一个标准大小的无味的口香糖,在这期间可连续手机唾液。

该方法检测血红蛋白水平的敏感性和特异性分别为0.759和0.763,检测乳酸脱氢酶水平的敏感性和特异性分别为0.711和0.722。结合这两个测试,当样品中血红蛋白和乳酸脱氢酶的检测为阳性时,阳性预测值为91.7%。

总而言之,与社区牙周指数检测相比,检测唾液中的血红蛋白和乳酸脱氢酶的水平则是相对来说创伤性较小的检测方法。因此,牙周筛查中,我们的唾液测试或是社区牙周指数的一个可行的替代方法。

原始出处:

Nomura Y, Okada A, Kakuta E, Gunji T, Kajiura S, Hanada N. A new screening method for periodontitis: an alternative to the community periodontal index.  BMC Oral Health. 2016 Jun 2;16(1):64.


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    2016-07-28 shizhenshan
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    2016-10-11 1e10c84am36(暂无匿称)

    好文章,受益

    0

  4. 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channel=null, level=null, likeNumber=40, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=13445, encryptionId=1584134451c, topicName=Oral)], attachment=null, authenticateStatus=null, createdAvatar=http://thirdwx.qlogo.cn/mmopen/vi_32/Q0j4TwGTfTIpeueeYB1kem1yfEZrSYKBdZBoqac9USf0RxIgRICBIyDn4licyiaiakNnobeCDVpvwqaWgwTNeLRHA/132, createdBy=bb5e2500127, createdName=小几洁, createdTime=Mon Aug 15 06:00:00 CST 2016, time=2016-08-15, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=123862, encodeId=7671123862a7, content=赞了!深度好文,学习学习。, beContent=null, objectType=article, channel=null, level=null, likeNumber=63, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo7s7ZCKOmmbBTD6nE7gcd5OZpvyGEzkxBP3S275k5ZJVrsPkotZhBglRHM9rKvcj1OgkssqhcnoPw8zIaMZTF8c/0, createdBy=4c441942088, createdName=ylzr123, createdTime=Mon Sep 12 19:08:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=123396, encodeId=332f1233963b, content=文章不错, beContent=null, objectType=article, channel=null, level=null, likeNumber=74, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Mon Sep 12 10:45:00 CST 2016, time=2016-09-12, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=122302, encodeId=d21b1223029e, content=己拜读,受益匪浅, beContent=null, objectType=article, channel=null, level=null, likeNumber=71, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 11 09:58:00 CST 2016, time=2016-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96472, encodeId=be02964e2f9, content=唾液用来筛查, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Sat Aug 06 21:16:00 CST 2016, time=2016-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92996, encodeId=e5e59299619, content=吐一口唾液就可以做检查, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Wed Jul 13 20:21:00 CST 2016, time=2016-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450475, encodeId=f5e714504e5f7, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Jul 12 04:00:00 CST 2016, time=2016-07-12, status=1, ipAttribution=)]
    2016-08-15 小几洁
  5. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450475, encodeId=f5e714504e5f7, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Jul 12 04:00:00 CST 2016, time=2016-07-12, status=1, ipAttribution=)]
    2016-09-12 ylzr123

    赞了!深度好文,学习学习。

    0

  6. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450475, encodeId=f5e714504e5f7, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Jul 12 04:00:00 CST 2016, time=2016-07-12, status=1, ipAttribution=)]
    2016-09-12 1e10c84am36(暂无匿称)

    文章不错

    0

  7. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450475, encodeId=f5e714504e5f7, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Jul 12 04:00:00 CST 2016, time=2016-07-12, status=1, ipAttribution=)]
    2016-09-11 1e10c84am36(暂无匿称)

    己拜读,受益匪浅

    0

  8. 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createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 11 09:58:00 CST 2016, time=2016-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=96472, encodeId=be02964e2f9, content=唾液用来筛查, beContent=null, objectType=article, channel=null, level=null, likeNumber=67, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Sat Aug 06 21:16:00 CST 2016, time=2016-08-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=92996, encodeId=e5e59299619, content=吐一口唾液就可以做检查, beContent=null, objectType=article, channel=null, level=null, likeNumber=60, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=/v1.0.0/img/user_icon.png, createdBy=a37a1710612, createdName=oo902, createdTime=Wed Jul 13 20:21:00 CST 2016, time=2016-07-13, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450475, encodeId=f5e714504e5f7, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Jul 12 04:00:00 CST 2016, time=2016-07-12, status=1, ipAttribution=)]
    2016-08-06 oo902

    唾液用来筛查

    0

  9. 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ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1450475, encodeId=f5e714504e5f7, content=<a href='/topic/show?id=f0476e49582' target=_blank style='color:#2F92EE;'>#牙周#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=35, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=67495, encryptionId=f0476e49582, topicName=牙周)], attachment=null, authenticateStatus=null, createdAvatar=null, createdBy=ab585558129, createdName=liuyong2982, createdTime=Tue Jul 12 04:00:00 CST 2016, time=2016-07-12, status=1, ipAttribution=)]
    2016-07-13 oo902

    吐一口唾液就可以做检查

    0

  10. 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