Neurology:预防痴呆理想的方法:保持健康!

2018-03-19 佚名 中国生物技术网

尽管这看起来有点违反直觉,但是痴呆和身体健康之间存在非常密切的关联。不断有研究发现,保持身体健康能够显着降低步入老年后患痴呆的风险。3月14日发表在《Neurology》的一项新研究也确认了这一观点。该研究报告称,身体健康的女性患痴呆症的可能性小得多,即使发病也要晚很多,其平均年龄高达90岁,而身体健康水平一般的女性则是79岁。

一项新研究发现,相比健康水平一般的女性,身体健康水平高的女性患痴呆的风险低90%。

尽管这看起来有点违反直觉,但是痴呆和身体健康之间存在非常密切的关联。不断有研究发现,保持身体健康能够显着降低步入老年后患痴呆的风险。3月14日发表在《Neurology》的一项新研究也确认了这一观点。该研究报告称,身体健康的女性患痴呆症的可能性小得多,即使发病也要晚很多,其平均年龄高达90岁,而身体健康水平一般的女性则是79岁。

瑞典哥德堡大学的Helena Horder博士是这项研究的作者,他说:“这项发现非常令人兴奋,因为我们能够通过在中年时期改善心血管健康来延缓甚至是防止痴呆症的发生。然而,该研究并未揭示出心血管健康与痴呆症之间的因果关系,它只表明了相关性。我们还需要更多的研究来证实,改善健康状况是否能够对降低痴呆风险产生积极影响,以及在生命中的哪个阶段保持高健康水平最为重要。”

该研究招募了191名平均年龄在50岁的女性志愿者。这些女性接受了骑自行车锻炼的体能测试,以此来评估她们的峰值心血管能力。研究人员测试出工作量平均峰值为103瓦特,有40名女性达到了120瓦特的高健康水平标准,93名女性处于中等健康水平,还有59名女性处于低健康水平,即峰值心血管能力在80瓦特以下(或者因高血压或其他身体原因无法完成测试)。之后,研究人员对这些女性进行了44年的追踪,总共进行了6次痴呆测试。结果如下:

研究中因身体原因无法完成测试的女性,在接下来的几十年中患痴呆的比例是45%。

Horder说:“这表明,这表明中年时期的心血管问题可能会在很大程度上增加痴呆症的风险。”

该结果表明体育运动和痴呆症发生之间存在很强的关联。然而,该研究存在三处明显的不足。

首先,虽然该研究持续了很长的时间,但是191人仍然是个小样本。此外,所有的参与者都是瑞典人,且是女性,因此无法保证该结果适用于其他人。最后,她们的身体健康水平只被测试了一次,很有可能在研究期间发生变化,无论是向好还是向坏。

尽管如此,越来越多的证据表明,保持健康确实对大脑有好处,它是防止痴呆发生的最好方法之一。反之,肥胖与痴呆症之间也存在正相关性。

原始出处:

Horder H,et al.Midlife cardiovascular fitness and dementia: A 44-year longitudinal population study in women.Neurology. 2018 Mar 14. pii: 10.1212/WNL.0000000000005290.

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    2018-08-02 yinhl1978
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  3. [GetPortalCommentsPageByObjectIdResponse(id=2000363, encodeId=d2c62000363b3, content=<a href='/topic/show?id=d5df12695e6' target=_blank style='color:#2F92EE;'>#Neurol#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=21, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=12695, encryptionId=d5df12695e6, topicName=Neurol)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=8217292, createdName=yinhl1978, createdTime=Thu Aug 02 17:04:00 CST 2018, time=2018-08-02, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1820158, encodeId=64441820158b2, content=<a href='/topic/show?id=97011003512e' target=_blank style='color:#2F92EE;'>#预防痴呆#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=37, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=100351, encryptionId=97011003512e, topicName=预防痴呆)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=467c360, createdName=yuanming7, createdTime=Tue Nov 06 04:04:00 CST 2018, time=2018-11-06, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=301642, encodeId=955f30164259, content=事实好像就是这样.长寿村的老人都是记忆力超好.牙齿好.吃的好, beContent=null, objectType=article, channel=null, level=null, likeNumber=50, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://cdnapi.center.medsci.cn/medsci/head/2018/03/24/965105b95fe53b6329b522fe372907a2.jpg, createdBy=34621617558, createdName=zanzaifeng, createdTime=Sun Apr 01 07:34:23 CST 2018, time=2018-04-01, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298670, encodeId=ee922986e096, content=了解一下, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/NUyjXTCJjo6KcicAVC1MwuOgo3iaicb1Imgk1yIfnvr6oXzibcAFB6puAyNJXbzWhNuLqaFYBVRWjh7rghkvFLPxMAfD5ib3nXwVD/0, createdBy=bed21972958, createdName=wxl882001, createdTime=Thu Mar 22 18:11:20 CST 2018, time=2018-03-22, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=298030, encodeId=65ea29803099, content=学习了谢谢了, beContent=null, objectType=article, channel=null, level=null, likeNumber=57, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/mONcle9pic3zSn0GqHrsfLPeNmuNF9ibgMfMOAs7Iic5MpiaU8RLmRH67xCKuk5wzfhb7G4ib7ia6z9lrnsTicj1nAUfEOMecZDtvvu/0, createdBy=d7f91939785, createdName=186****0580(小山羊), createdTime=Tue Mar 20 09:46:14 CST 2018, time=2018-03-20, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=297837, encodeId=d26629e83740, content=精简.有道理., beContent=null, objectType=article, channel=null, level=null, likeNumber=49, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=http://cacheapi.medsci.cn/resource/upload/20161224/IMG585DA5E26B9F44696.jpg, createdBy=565a98798, createdName=susice, createdTime=Mon Mar 19 23:08:22 CST 2018, time=2018-03-19, status=1, ipAttribution=)]
    2018-04-01 zanzaifeng

    事实好像就是这样.长寿村的老人都是记忆力超好.牙齿好.吃的好

    0

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    2018-03-22 wxl882001

    了解一下

    0

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    2018-03-20 186****0580(小山羊)

    学习了谢谢了

    0

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    2018-03-19 susice

    精简.有道理.

    0

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