EJCN:绿茶的又一功效!加快胃癌患者手术后的康复速度

2021-03-26 生物探索 生物探索

饮用绿茶或许有助于提高胃切除术治疗胃癌后的患者康复率。

胃癌,是一种起源于胃黏膜上皮的恶性肿瘤。在我国,胃癌发病率居各种恶性肿瘤之首,目前早期诊断率仍然较低。尽管手术切除是提高胃癌患者生存率的唯一适宜疗法,但是术后的并发症发生率和死亡率分别达到12.5-18.3%和0.5-1.2%。如何进一步促进患者康复,成为现代医学的研究热点。

近日,青岛大学附属医院胃肠外科的研究人员在《European Journal of Clinical Nutrition》上发表了题为Impact of drinking Chinese green tea on postoperative short outcomes for gastric cancer: a randomized controlled trial的研究报告,探讨了胃癌手术后饮用绿茶对于患者康复的影响。

在先前的探索中,研究人员已经发现,术后早期摄入液体和食物能够促进患者康复,而不会增加瘘管的发生率。不过,对于摄入哪一种液体或食物对患者更有益,目前仍然存在较大的争论。

在中国,绿茶是最常见的饮品之一,富含儿茶素、多类氨基酸和咖啡因等物质,具有多种抗氧化、抗炎症、降胆固醇、抗动脉硬化和抗菌等多重药理特性。于是,研究人员探讨了在胃癌手术后摄入绿茶对术后康复的影响。

2017年9月至2018年9月期间,共有80位胃癌患者接受了手术治疗,40位患者在术后饮用按照1:200(绿茶:水)的比例制成的茶饮品,另外40位患者则摄入饮用水。主要结果是患者胃肠功能恢复情况,评价标准为术后第一次肠胃排气、第一次肠蠕动以及对固体食物耐受的时间,次要结果包括术后并发症的发生率,恶心、呕吐、腹泻等不良反应,以及术后住院时间。

研究流程图

观察结果显示,术后饮用绿茶的患者胃肠功能恢复更好。在术后首次排气时间上,摄入饮用水的患者耗时76.96±20.35小时(h),而摄入绿茶组的数据为47.23±13.46,时间缩短了20%~38%不等。不仅如此,绿茶的摄入还将患者首次排便的时间缩短了32%~61%(78.70±25.77 vs.125.76±36.25),对固体食物耐受的平均时间缩短了28%~45%(62.20±16.15 vs.98.66±20.15)。

摄入绿茶组和摄入饮用水组第一次肠胃排气、第一次排便对固体食物耐受的时间比较。

TNF-α和PCT是测定患者炎症感染情况的重要标志物。数据显示,在术后第三天,饮用绿茶组的患者TNF-α和血清PCT均显着低于对照组,说明胃切除术后饮用绿茶能够产生一定的抗感染作用,并减少术后炎症反应。在不良反应方面,两组间差异并不显着。

总体而言,这项研究表明,饮用绿茶或许是一种有效的术后干预措施,能够提高胃切除术治疗胃癌后的患者康复率,同时也可以作为术后增强镇痛和抗炎作用的补充方法。

原始出处:

Liu, D., Jing, X., Cao, S. et al. Impact of drinking Chinese green tea on postoperative short outcomes for gastric cancer: a randomized controlled trial. Eur J Clin Nutr (2021). https://doi.org/10.1038/s41430-021-00868-8.

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    2021-07-15 黄昏晓Time

    😇统一绿茶还是康师傅,红茶有没有同样的作用😎

    0

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    2021-05-25 Courage44

    #学习#学习了

    0

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    2021-03-29 科研科研科研

    绿茶加快胃癌患者手术后的康复速度

    0

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    2021-03-29 189****1979

    绿茶有益于健康!

    0

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    2021-03-28 hbwxf
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    2021-03-27 sanchi2013

    学习了

    0

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