Diabetes Metab Syndr:非肥胖成人体重增加与代谢综合征的关系

2016-07-06 Seven L 译 MedSci原创

根据最近的研究结果,非肥胖的日本人,如果体重增加超过1年,将会与腰围和甘油三酯的增加有关,而后两者是代谢综合征的诊断标准。御茶水女子大学的Shiori Toga和和同事们分析了1653名年龄24到63年的日本人的数据(平均年龄39岁;698名男性;平均BMI 20.5 kg/m2)。纳入了体重增加超过1年,但仍然没有肥胖(BMI 25 kg/m2或更少)的成年人。随访一年后研究人员评估了参与者的腰

根据最近的研究结果,非肥胖的日本人,如果体重增加超过1年,将会与腰围和甘油三酯的增加有关,而后两者是代谢综合征的诊断标准。

御茶水女子大学的Shiori Toga和和同事们分析了1653名年龄24到63年的日本人的数据(平均年龄39岁;698名男性;平均BMI 20.5 kg/m2)。纳入了体重增加超过1年,但仍然没有肥胖(BMI 25 kg/m2或更少)的成年人。随访一年后研究人员评估了参与者的腰围、舒张压和收缩压、空腹血糖、甘油三酯和高密度脂蛋白胆固醇等所有代谢综合征的诊断标准相关参数。

根据体重增加情况分为4组:0–0.99 kg (对照;N=696 (42.1%)); 1–1.99 kg(N=514 (31.1%)); 2–2.99 kg(N=251 (15.2%));至少3 kg(N=192 (11.6%))。

研究人员观察到在所有四个体重增加组的性别差异(P = .008)。对于男性,腹围、血压和甘油三酯水平存在组间差异,体重增加越多,心脏代谢有关参数指标情况越差。4各不同体重增加组的腹围增加分为别0.6 cm、1.55 cm、2.86 cm和4.42 cm。男性增加至少3 kg组的参与者与对照组相比,有最高的舒张压和甘油三酯水平(3.36 mm Hg vs. 0.11 mm Hg; 27.3 mg/dL vs. 0.63 mg/dL)。

不同体重增加组女的腹围无差异。增加至少3 kg组与对照组相比,甘油三酯水平最高(29.8 mg/dL vs. 5.01 mg/dL)。

据研究人员说,无论是在男性还是女性,1年来,空腹血糖或高密度脂蛋白胆固醇都不受影响。

“在日本,腹围作为一种衡量内脏脂肪堆积的指标,”研究人员写道。“我们的研究表明,体重和腹围是有用的代谢综合征指数。一般来说,相比腹围,体重是更容易进行测量的,每天的体重检查对衡量内脏脂肪积累风险的衡量是有用的。”

原始出处:


Toga S, et al. Relationship between weight gain and metabolic syndrome in non-obese Japanese adults.Diabetes Metab Syndr. 2016;doi:10.1016/j.dsx.2015.09.004

Weight gain over 1 year increases metabolic syndrome parameters in non-obese adults.
Healio.July 4, 2016


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  4. 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objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 11 09:58:00 CST 2016, time=2016-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298203, encodeId=62431298203bd, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Fri Jul 08 05:44:00 CST 2016, time=2016-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1430637, encodeId=1bda143063ecc, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Fri Jul 08 05:44:00 CST 2016, time=2016-07-08, status=1, ipAttribution=)]
    2016-08-29 guojianrong
  5. 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  6. 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objectType=article, channel=null, level=null, likeNumber=66, replyNumber=0, topicName=null, topicId=null, topicList=[], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/jW482SpianMayicTRbRZ5RzdAIB7UwTkHt6fQkBP8ictliaXtc5gCUmYdAW1sAETC2nhO3q6YjRHkUibyOCtP8ibmXNObTyd63A076/0, createdBy=d4111948983, createdName=1e10c84am36(暂无匿称), createdTime=Sun Sep 11 09:58:00 CST 2016, time=2016-09-11, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1298203, encodeId=62431298203bd, content=<a href='/topic/show?id=3379266918f' target=_blank style='color:#2F92EE;'>#体重增加#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=28, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=26691, encryptionId=3379266918f, topicName=体重增加)], attachment=null, authenticateStatus=null, createdAvatar=, createdBy=45b2276, createdName=839640778, createdTime=Fri Jul 08 05:44:00 CST 2016, time=2016-07-08, status=1, ipAttribution=), GetPortalCommentsPageByObjectIdResponse(id=1430637, encodeId=1bda143063ecc, content=<a href='/topic/show?id=f9b9e9124a8' target=_blank style='color:#2F92EE;'>#综合征#</a>, beContent=null, objectType=article, channel=null, level=null, likeNumber=25, replyNumber=0, topicName=null, topicId=null, topicList=[TopicDto(id=79124, encryptionId=f9b9e9124a8, topicName=综合征)], attachment=null, authenticateStatus=null, createdAvatar=https://wx.qlogo.cn/mmopen/aLGWoFXAyMbIu3qymFOyheQLjPSX3OUs5GmkyBlcCOwTPIeq3why9NGibxxUqYo6hcx8qZLHZFgNPnBK1yzWeOFpyg2OnWOt0/0, createdBy=fa4716, createdName=zhouqu_8, createdTime=Fri Jul 08 05:44:00 CST 2016, time=2016-07-08, status=1, ipAttribution=)]
    2016-09-21 1e10c84am36(暂无匿称)

    文章很好,非常有益

    0

  7. 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    2016-09-13 舒心和人

    肥胖真不是一件好事,避免成为一个苦恼的胖纸,从管住嘴迈开腿开始

    0

  8. 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    2016-09-11 1e10c84am36(暂无匿称)

    己拜读,受益匪浅

    0

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