JACC:橄榄油摄入量和心血管疾病风险

2020-03-14 MedSci原创 MedSci原创

由此可见,较高的橄榄油摄入量与较低的冠心病和总心血管疾病风险相关。用橄榄油代替人造奶油、黄油、蛋黄酱和乳制品脂肪可以降低患冠心病和心血管疾病的风险。 

在地中海人群中,橄榄油的摄入量与较低的心血管疾病(CVD)风险有关,但在美国,人们对这些相关性知之甚少。近日,心血管领域权威杂志JACC上发表了一篇研究文章,该研究旨在探讨橄榄油摄入量与全脑血管疾病、冠心病(CHD)和卒中风险之间的关系。

该研究纳入了来自护士健康研究(1990-2014)的61181名女性和来自健康专家随访研究(1990-2014)的31797名男性,他们在基线时没有癌症、心脏病和卒中。在基线和每4年使用食物频率问卷对饮食进行评估。Cox比例风险回归用于估计风险比(HR)和95%置信区间(CI)。

在24年的随访中,研究人员共记录了9797例心血管疾病,包括6034例冠心病和3802例卒中病例。在对主要饮食和生活方式因素进行调整后,与非摄入者相比,那些橄榄油摄入量较高(>1/2汤匙/天或>7g/天)的个体患心血管疾病的风险降低了14%[合并HR(95%CI): 0.86(0.79-0.94)],而冠心病的风险降低了18%[合并HR(95%CI): 0.82(0.73-0.91)]。对于全脑卒中和缺血性卒中未观察到明显相关性。用等量的橄榄油替代5g/天的人造奶油、黄油、蛋黄酱或乳制品脂肪,可降低5-7%的心血管疾病和冠心病风险。当橄榄油与其它植物油组合摄入时,没有观察到明显的关联。在一个亚组中,较高的橄榄油摄入量与较低的循环炎症生物标志物水平和较好的血脂水平相关。

由此可见,较高的橄榄油摄入量与较低的冠心病和总心血管疾病风险相关。用橄榄油代替人造奶油、黄油、蛋黄酱和乳制品脂肪可以降低患冠心病和心血管疾病的风险。 

原始出处:

Marta Guasch-Ferré.et al.Olive Oil Consumption and Cardiovascular Risk in U.S. Adults.Journal of the American College of Cardiology.2020;http://www.onlinejacc.org/content/early/2020/02/27/j.jacc.2020.02.036

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    2020-11-24 hbwxf
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    2020-11-13 lmm397
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